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Displaying drugs 276 - 300 of 698 in total

Lym-1-I-131

Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma …

Etigilimab

Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized …
Matched Description: … Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab …

Milk thistle

Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Mariana Mariana Seed ... Carduus Marianus Seed ... Silybum Marianum Seed …
Matched Categories: … Herbs and Natural Products …
Matched Products: … SILYBUM MARIANUM SEED Extract …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Gentle and Effective Laxative Enteric Coated …

Tetryzoline

Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. ... 1950s, tetryzoline is a selective α1-receptor agonist [A231774] that is used as an ocular and …
Matched Mixtures name: … Redness reliever and Lubricant ... Seasonal itchy and Red eye relief ... Up and Up Ultra Itchy Relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops …

Xylometazoline

Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …

Acapatamab

Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and …
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …

Lorigerlimab

Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND ... ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND …

Tepilamide fumarate

Investigational
Matched Synonyms: … 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate …

Biotin

A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, …
Matched Mixtures name: … Luna Vitamin and Mineral Bar for Women ... Kanga Sport Vitamins B & C Plus Minerals ... Therapytion Nokmosu Sensitive and Dry Hair …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Enzymes and Coenzymes …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …

Garcinia gummi-gutta fruit

Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …

DCLL-9718S

DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults ... Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and ... essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Matched Products: … ZOMACTON Powder and Solvent for Solution for Injection 10mg ... ZOMACTON Powder and Solvent for Solution for Injection 4 mg ... GENOTROPIN® 12MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … withdrawal symptoms and to induce euphoria. ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A6249] Due to pharmacological properties, loperamide has been misused and abused to self-manage opioid …
Matched Mixtures name: … Loperamide Hydrochloride and Simethicone ... Up and Up Anti Diarrheal Anti Gas ... Anti Diarrheal and Anti Gas …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... Berkley and Jensen Anti Diarrheal ... Foster and Thrive Anti-diarrheal …

Dabocemagene autoficel

Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND …

Mucor circinelloides f. circinelloides

Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides ... Mucor circinelloides f. circinelloides whole …

Levomenthol

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … Hemo-pic ... SEE FULL OIL ... LUKE`S SPORTS OIL …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery ... Sport Cold - Gel - 2% …

Insulin aspart

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and proteolysis among many other functions. ... Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … Insulin Aspart Protamine and Insulin Aspart Mix 70/30 ... .Insulin Aspart Protamine and Insulin Aspart …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Categories: … Alpha and Beta Blocking Agents and Thiazides ... Alpha and Beta Blocking Agents ... Beta Blocking Agents and Thiazides ... labetalol and thiazides ... labetalol and other diuretics …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …

STRO-001

Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …

PRGN-3006

PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …

Demplatin pegraglumer

Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Olopatadine

Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … inflammatory and allergic reactions. ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …

Phenazopyridine

Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Description: … its associated unpleasant symptoms such as burning and pain during urination. ... Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief …

Ranitidine

Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … the same drug class as [cimetidine] and [famotidine]. ... Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to ... tablet, injection, and effervescent tablet preparations. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Ranitidine ... Berkley and Jensen Ranitidine ... Up and Up Ranitidine 150 …
Displaying drugs 276 - 300 of 698 in total