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Displaying drugs 276 - 300 of 10408 in total

Scorpion (centruroides) immune Fab2 antivenin (equine)

Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Description: … It was approved by FDA in 2011 and is marketed under the name Anascorp [L2196]. ... cause loss of muscle control and respiratory failure, warranting heavy sedation and hospitalization in an …

Carthamus tinctorius flower bud

Carthamus tinctorius flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Inonotus obliquus fruiting body

Inonotus obliquus fruiting body is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Deferasirox

Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Approved
Investigational
Matched Description: … Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload …
Matched Categories: … Chelating Agents ... Sequestering Agents ... Iron Chelating Agents …

Sparsentan

Sparsentan is a dual antagonist of the endothelin type A receptor (ETAR) and the angiotensin II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETAR and 0.8 nM for AT1R).[A257330,L45300] Sparsentan is first in its class and orally active, and was created by...
Approved
Investigational
Matched Description: … in adults with primary immunoglobulin A nephropathy (IgAN) at risk of rapid disease progression was approved ... AT1R antagonist, and biphenylsulfonamide, an ETAR antagonist. ... in its class and orally active, and was created by merging the structural elements of [irbesartan], an …
Matched Categories: … Agents Acting on the Renin-Angiotensin System …

Metreleptin

Metreleptin, a recombinant analog of the human hormone leptin, is an orphan drug used to treat complications of leptin deficiency in people with lipodystrophy. Lipodystrophies include a range of disorders characterized by the reduction, absence, or altered distribution of adipose tissue. Complications of lipodystrophy include metabolic abnormalities such as hypertriglyceridemia,...
Approved
Matched Description: … Metreleptin, a recombinant analog of the human hormone leptin, is an orphan drug used to treat complications ... [L41315] In February 2014, metreleptin was approved by the FDA for the treatment of complications ... [L41315] Metreleptin was approved by Health Canada in January 2024 for the same patient population, in …

Ambrosia artemisiifolia pollen

Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved

Linagliptin

Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Description: … Linagliptin was approved by the FDA on May 2, 2011[L9557]. …
Matched Categories: … Agents causing angioedema ... Blood Glucose Lowering Agents …

Dioxybenzone

Dioxybenzone, or benzophenone-8, is an organic compound derived from DB01878 that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% .
Approved
Matched Description: … Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525]. ... Dioxybenzone, or benzophenone-8, is an organic compound derived from [DB01878] that is used as a sunscreen …
Matched Categories: … Sunscreen Agents …

Doripenem

Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an ... Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal ... warning against use in ventilator-associated pneumonia and to reiterate its safety and efficacy for its approved …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Pyrantel

Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm infections including ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis . Pyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use...
Approved
Vet approved
Matched Description: … cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use as an …
Matched Categories: … Anti-Infective Agents ... Antinematodal Agents ... Antiparasitic Agents ... Neuromuscular Agents ... Neuromuscular Blocking Agents …

Pimethixene

Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. It is an anticholinergic used in the treatment of bronchitis.
Approved
Matched Description: … It is an anticholinergic used in the treatment of bronchitis. ... Pimethixene is approved for use in Brazil and is marketed under the trade name Muricalm. …

Ipecac

Ipecac is obtained from the plant Cephaelis ipecacuanha and contains a number of emetic alkaloids including emetine and cephaeline. Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. The FDA does not have currently any approved product containing ipecac, however, ipecac as an...
Approved
Withdrawn
Matched Description: … [L2753] Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. ... [L1113] The FDA does not have currently any approved product containing ipecac, however, ipecac as an …
Matched Categories: … Autonomic Agents ... Agents Causing Muscle Toxicity ... Gastrointestinal Agents ... Central Nervous System Agents ... Peripheral Nervous System Agents …

Regadenoson

Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Matched Categories: … Purinergic Agents ... Neurotransmitter Agents …

Ketazolam

Ketazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. Ketazolam is not approved in Canada or America.
Approved
Matched Description: … Ketazolam is not approved in Canada or America. …
Matched Categories: … Anti-Anxiety Agents ... Tranquilizing Agents ... Central Nervous System Agents …

Perboric acid

Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate or tetrahydrate. It is one of the peroxy acid salts with very wide functionalities in industrial settings. Perboric acid in the form of sodium perborate is approved by Health Canada...
Approved
Matched Description: … [L1113] By the FDA, sodium perborate is approved as an ointment for the protection of poison ivy dermatitis ... [F66] Perboric acid in the form of sodium perborate is approved by Health Canada since 2004 to be used …

Pralsetinib

Pralsetinib, similar to the previously approved selpercatinib, is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A219751, L15986] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers, including non-small cell lung cancer. Although multikinase inhibitors, including cabozantinib, ponatinib,...
Approved
Investigational
Matched Description: … Pralsetinib, similar to the previously approved [selpercatinib], is a kinase inhibitor with enhanced …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents …

Bismuth subgallate

Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Description: … Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration ... yet elucidated antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an …
Matched Categories: … Anti-Infective Agents ... Hematologic Agents ... Neurotoxic agents …

Pramiracetam

Pramiracetam has been previously approved in some eastern European countries under the brand names Pramistar, Neupramir, and Remen. It was also previously approved in the United States with orphan drug designation . Pramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive...
Approved
Matched Description: … Pramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore ... It was also previously approved in the United States with orphan drug designation [L1469]. ... Pramiracetam has been previously approved in some eastern European countries under the brand names Pramistar …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Fluorometholone

A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Approved
Investigational
Matched Categories: … Corticosteroids, Moderately Potent (Group II) ... Anti-Allergic Agents ... Anti-Inflammatory Agents ... Immunosuppressive Agents ... Hyperglycemia-Associated Agents …

Antilymphocyte immunoglobulin (horse)

Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Description: … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune …
Matched Categories: … Immunosuppressive Agents ... Miscellaneous Therapeutic Agents ... Antineoplastic and Immunomodulating Agents …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Categories: … Protective Agents ... Respiratory System Agents …
Matched Products: … Truemed Group LLC …

Ginkgo biloba

Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Description: … _Ginkgo biloba_ extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ... a number of homeopathic and over-the-counter herbal products and dietary supplements, but it has no approved ... [L32789] _Ginkgo biloba_ is an herbal plant that is now cultivated worldwide. …
Matched Categories: … Cardiovascular Agents …

Eprosartan

Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Description: … Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. …
Matched Categories: … Hypotensive Agents ... Agents causing angioedema ... Cardiovascular Agents ... Agents causing hyperkalemia ... Antihypertensive Agents …

Penbutolol

Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Categories: … Antidepressive Agents ... Adrenergic Agents ... Serotonin Agents ... Hypotensive Agents ... Cardiovascular Agents …
Displaying drugs 276 - 300 of 10408 in total