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Displaying drugs 276 - 300 of 14986 in total

Xylometazoline

Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …

Rifampin

Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Description: … rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and ... [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Kerasal foot and toe ... Up and Up Athletes Foot ... Protective Nail and skin …

Lamivudine

A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine and abacavir ... stavudine and lamivudine ... zidovudine and lamivudine …
Matched Products: … Lamivudine and Zidovudine …

Velpatasvir

Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Iupac: … methyl N-[(1R)-2-[(2S,4S)-2-(5-{6-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]-5-methylpyrrolidin …
Matched Description: … SVR and eradication of HCV infection is associated with significant long-term health benefits including ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus …
Matched Mixtures name: … Sofosbuvir and Velpatasvir …
Matched Categories: … Hepatitis C Virus NS5A Inhibitor ... sofosbuvir and velpatasvir ... sofosbuvir, velpatasvir and voxilaprevir …

Castor oil

Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … cosmetic, hair, and skincare products. ... and mineral oral tablets as an ingredient for protective coatings. ... of the castor oil plant (_Ricinus communis_ L.) mainly cultivated in India, South America, Africa, and …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil …

Testosterone

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.
Approved
Investigational
Matched Description: … development of masculine sex organs and secondary sexual characteristics. ... Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism ... [A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also …
Matched Categories: … Androgens and Estrogens ... testosterone and estrogen ... Testosterone and derivatives ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Levomenthol

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … Jack and Jill Rub ... Half and Half Balm ... Satohap Cool and Hot Pads …
Matched Categories: … Basic Lotions and Liniments ... Herbs and Natural Products ... Antipruritics and Local Anesthetics ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery …

Hyaluronidase (human recombinant)

A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Description: … fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. ... [A4033] Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Hyaluronidase

Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. ... Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Belatacept

Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Investigational
Matched Description: … Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated ... it is a homodimer of two homologous polypeptide chains of 357 amino acids each. ... antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Rimantadine

An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …

D-Serine

A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem]
Approved
Experimental
Matched Iupac: … (2R)-2-amino-3-hydroxypropanoic acid …
Matched Description: … It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem] ... A non-essential amino acid occurring in natural form as the L-isomer. …

Ubidecarenone

Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative ... [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant …
Matched Mixtures name: … Vitamin E and Coq10 ... Co-q10 and Vitamin E ... Co-q10 M.R.B. 100mg and Vitamin E …
Matched Categories: … Hypoglycemia-Associated Agents ... Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …

Pyridoxal phosphate

This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Description: … This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Propanoic acid

Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder. It is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent. Its use as a food...
Approved
Vet approved
Matched Description: … as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and ... Sodium propionate was previously approved in Canada as an active ingredient in Amino-Cerv (used to treat …
Matched Mixtures name: … Amino-cerv …

Cerivastatin

On August 8, 2001 the U.S. Food and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew Baycol from the U.S. market, due to reports of fatal rhabdomyolysis, a severe adverse reaction from this cholesterol-lowering (lipid-lowering) product. It has also been withdrawn from the Canadian market.[A669,L43942]
Approved
Withdrawn
Matched Description: … Food and Drug Administration (FDA) announced that Bayer Pharmaceutical Division voluntarily withdrew …

Daratumumab

Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. Daratumumab was granted FDA approval on 16 November 2015. It is approved for...
Approved
Matched Description: … Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. ... [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Cystine

A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
Approved
Nutraceutical
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-2-carboxyethyl]disulfanyl}propanoic acid …
Matched Description: … A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. …
Matched Mixtures name: … Amino-cerv …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Diamino ... Amino Acids, Sulfur ... Amino Acids, Dicarboxylic …

Tenofovir disoproxil

Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Iupac: … bis({[(propan-2-yloxy)carbonyl]oxy}methyl) {[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methanephosphonate …
Matched Mixtures name: … Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... tenofovir disoproxil and emtricitabine …

Esomeprazole

Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … Long term use of PPIs such as esomeprazole has been associated with possible adverse effects, however ... and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... naproxen and esomeprazole ... Antiinflammatory and Antirheumatic Products ... esomeprazole, amoxicillin and clarithromycin …
Matched Products: … Up and Up Esomeprazole Magnesium ... Foster and Thrive Acid Reducer ... Berkley and Jensen Heartburn Treatment …

alpha-Tocopherol acetate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Description: … d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... At the moment however, there exists a lack of formal data and evidence to support any such additional ... This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether …
Matched Mixtures name: … Chunzam Silk Amino Acid Tooth ... Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …

Carbamazepine

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1....
Approved
Investigational
Matched Description: … and to treat pain resulting from trigeminal neuralgia. ... Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures …

Ecallantide

Ecallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema. Ecallantide is a recombinant 60-amino-acid protein produced in Pichia pastoris yeast cells that contains three intramolecular disulfide bonds [FDA Label]. It was discovered by phage display technology . It shares...
Approved
Investigational
Matched Description: … The disorder is associated with recurrent attacks of severe swelling and is thought to be caused by unregulated ... The amino acid sequence of two compounds differ by seven amino acids [L1458]. ... naturally occurring human protein tissue-factor pathway inhibitor (TFPI), which is also known lipoprotein-associated …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …

Brentuximab vedotin

Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … death due to opportunistic JC virus infection post-treatment. ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. ... Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Displaying drugs 276 - 300 of 14986 in total