Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 3001 - 3025 of 3344 in total

2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid

Experimental
Matched Name: … 2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid …
Matched Iupac: … 2-{3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}acetic acid …

2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID

Experimental
Matched Name: … CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID …
Matched Iupac: … )-carboxy[2-(thiophen-2-yl)acetamido]methyl]-5-methylidene-5,6-dihydro-4H-1,3-thiazine-4-carboxylic acid …

Thalidomide

A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha...
Approved
Investigational
Withdrawn
Matched Synonyms: … N-Phthalylglutamic acid imide …
Matched Description: … It has been reintroduced and used for a number of inflammatory disorders and cancers. ... inflammatory mediators like tumor necrosis factor-alpha (TNF-a) and other cytokine action. ... Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Carboxylic Acids …

Thiotepa

N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. It is also used as conditioning for Bone marrow...
Approved
Investigational
Matched Description: … It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. ... It is also used as conditioning for Bone marrow transplantation. ... triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Thiotepa for Injection USP ... Thiotepa for Injection, BP …

Flumazenil

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …
Matched Products: … Flumazenil Kabi 0.1 mg/mL Solution for Injection ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 1 MG/10 ML ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 0.5 MG/5 ML …

Ofatumumab

Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … In Phase III clinical trials consisting of subjects with relapsing forms of multiple sclerosis (RMS), ... [A6921] Ofatumumab is available for intravenous administration and is marketed as Arzerra. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 20MG/0.4ML …

METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE

Experimental
Matched Name: … METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE …
Matched Iupac: … methyl 1-(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoyl)piperidine-4-carboxylate …

Fosaprepitant

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Iupac: … ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid …
Matched Description: … It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment …
Matched Categories: … Aprepitant and Prodrugs …
Matched Products: … Powder for Solution for Infusion 150mg …

Risdiplam

Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Description: … substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a novel and ... Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular ... relatively accessible treatment option for patients with SMA regardless of severity or type. …
Matched Products: … Evrysdi Powder for oral solution 0.75 mg/mL ... EVRYSDI POWDER FOR ORAL SOLUTION 0.75 MG/ML …

N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid

Experimental
Matched Name: … ]-L-glutamic acid ... methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl …
Matched Iupac: … -5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-5-yl}prop-2-enamido]phenyl}formamido)pentanedioic acid …

Technetium Tc-99m sulfur colloid

Technetium 99m sulfur colloid is a radiopharmaceutical diagnostic agent used in the evaluation of various conditions including lymph node metastases in breast cancer, detection of shunt patency, imaging of reticuloendothelial cells for assessment of liver function, and studies of esophageal transit and gastroesophageal reflux. Following injection or oral administration, single...
Approved
Investigational
Matched Description: … assessment of liver function, and studies of esophageal transit and gastroesophageal reflux. ... Depending on site of administration and intended usage, Technetium 99m sulfur colloid enters the capillaries ... and is transported to the lymph nodes (subcutaneous injection), mixes with peritoneal fluid (intraperitoneal …
Matched Categories: … Indicators and Reagents ... Hepatic and Reticulo Endothelial System ... Technetium (99Mtc), Particles and Colloids …
Matched Products: … Kit for the Prepartion of Technetium Tc99m Sulfur Colloid ... Kit for the Preparation of Technetium Tc 99m Sulfur Colloid …

Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)

Approved
Investigational
Matched Mixtures name: … Tetanus and Diphtheria Toxoids Adsorbed for Adult Use ... Diphtheria and Tetanus Toxoids Adsorbed ... Tetanus and Diphtheria Toxoids Adsorbed …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … Diphtheria Toxoid for Reaction Test 0.2lf/ml ... Diphtheria Toxoid for Schick Control 0.2lf/ml …

Cefmenoxime

Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Approved
Matched Synonyms: … amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … used in the treatment of female gynecologic and obstetric infections. ... Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically ... It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Lixadesiran

Investigational
Matched Synonyms: … Stp-705 component anti-cox2 si-rna free acid …

DPM-1001

Investigational
Matched Synonyms: … Cholan-24-oic acid, 7-hydroxy-3-[[4-[(2-pyridinylmethyl)amino]butyl]amino]-, methyl ester, (3β,5α,7α) …

Mitomycin

Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Description: … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations ... , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper Tract …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Indicators and Reagents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Mitomycin for Injection ... Mitomycin for Injection USP ... Mitomycin for Injection, USP …

Anidulafungin

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
Approved
Investigational
Matched Description: … Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … ANIDACCORD 100 POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG ... ERAXIS 100MG FOR INJECTION ... Eraxis 100mg For Injection …

L-arginine

Approved
Nutraceutical
Matched Mixtures name: … AMINOVEN SOLUTION FOR INFUSION 15% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Essential …
Matched Products: … LYSAKARE SOLUTION FOR INFUSION 25G / 25G …

Lutein

Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. In green plants, xanthophylls act to modulate light energy and serve as...
Approved
Investigational
Nutraceutical
Matched Description: … to deal with triplet chlorophyll (an excited form of chlorophyll), which is overproduced at very high ... Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. ... leafy vegetables such as spinach, kale and yellow carrots. …
Matched Products: … Noon for Kids …

Sotrovimab

Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Description: … [L34425, L34430, L34440] However, in April 2022, the FDA removed the EUA for sotrovimab due to the rising …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use ... Approved Treatments for COVID-19 ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … Sotrovimab for Injection …

Insulin degludec

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, ... Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused ... [A18561,A18562,A18563,A18564,A174934] As a result, people with T1D rely primarily on exogenous forms …
Matched Mixtures name: … Ryzodeg® FlexTouch® 100 U/ml Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Tresiba ® FlexTouch® 100 U/ml Solution for Injection ... Tresiba ® Flextouch® 200 U/mL Solution for Injection ... TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 100 U/ML …

Palonosetron

Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Synonyms: … (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one …
Matched Description: … and treatment of chemotherapy-induced nausea and vomiting (CINV). ... Food and Drug Administration. ... class approved for this use by the U.S. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Solution for Injection 50mcg/ml ... ALOXI Solution for Injection 50mcg/ml ... PALSET (Palonosetron Hydrochloride Solution for Injection 0.05 mg/ml, 5 ml vial) …

Pembrolizumab

Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … [F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma ... as interchain bonds and 23 interchain bonds. ... [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … Keytruda 100mg Solution for Infusion ... KEYTRUDA SOLUTION FOR INFUSION 25MG/ML …

Flax seed

Flax seed allergenic extract is used in allergenic testing.
Approved
Matched Products: … Flax Seed for Diagnostic Use Only …

Flutemetamol

Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).
Investigational
Matched Categories: … Indicators and Reagents …
Matched Products: … VIZAMYL SOLUTION FOR INJECTION 150 MBq/mL …
Displaying drugs 3001 - 3025 of 3344 in total