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Displaying drugs 3026 - 3050 of 8399 in total

Daphnetin

Daphnetin is under investigation in clinical trial NCT06329167 (Daphnetin Capsules for Lower Limb Lymphoedema Following Gynaecological Surgery).
Investigational
Matched Synonyms: … 2h-1-benzopyran-2-one, 7,8-dihydroxy- ... 7,8-dihydroxy-2h-1-benzopyran-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

(4R,5R)-1,2-dithiane-4,5-diol

Experimental

(4S,5S)-1,2-dithiane-4,5-diol

Experimental

8-oxo-dGMP

Experimental
Matched Synonyms: … 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid ... 8-hydroxydeoxyguanosine 5'-monophosphate ... 8-oxo-2'-deoxyguanosine-5'-monophosphate …
Matched Iupac: … {[(2R,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …

(5R)-4-HYDROXY-3,5-DIMETHYL-5-[(1E,3E)-2-METHYLPENTA-1,3-DIENYL]THIOPHEN-2(5H)-ONE

Experimental
Matched Name: … (5R)-4-HYDROXY-3,5-DIMETHYL-5-[(1E,3E)-2-METHYLPENTA-1,3-DIENYL]THIOPHEN-2(5H)-ONE …
Matched Iupac: … (5R)-4-hydroxy-3,5-dimethyl-5-[(1E,3E)-2-methylpenta-1,3-dien-1-yl]-2,5-dihydrothiophen-2-one …

BNT-162A1

BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).
Investigational
Matched Categories: … COVID-19 Vaccines …

Prexasertib

Prexasertib has been used in trials studying the treatment and basic science of mCRPC, Leukemia, Neoplasm, breast cancer, and Ovarian Cancer, among others.
Investigational
Matched Iupac: … 5-({5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl}amino)pyrazine-2-carbonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE

Experimental
Matched Name: … 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE …
Matched Iupac: … 3-(hydroxymethyl)-1-methyl-5-[(1S,2R)-2-methylaziridin-1-yl]-2-phenyl-4,7-dihydro-1H-indole-4,7-dione …

Icotinib

Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a “May Proceed” from the US FDA to conduct a Phase I study for the...
Experimental
Investigational

Pentaglobin

Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations. It is comprised of immunoglobulin G (IgG) (https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).
Investigational

Proxalutamide

Proxalutamide is under investigation in clinical trial NCT03899467 (The Safety and Tolerability of Proxalutamide (GT0918) in Subjects With Metastatic Castrate Resistant Prostate Cancer).
Investigational
Matched Iupac: … 4-(4,4-dimethyl-3-{6-[3-(1,3-oxazol-2-yl)propyl]pyridin-3-yl}-5-oxo-2-sulfanylideneimidazolidin-1-yl) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-[(2,4-DICHLORO-5-METHYLPHENYL)SULFONYL]-1,3-DINITRO-5-(TRIFLUOROMETHYL)BENZENE

Experimental
Matched Name: … 2-[(2,4-DICHLORO-5-METHYLPHENYL)SULFONYL]-1,3-DINITRO-5-(TRIFLUOROMETHYL)BENZENE …
Matched Iupac: … 1,5-dichloro-2-[2,6-dinitro-4-(trifluoromethyl)benzenesulfonyl]-4-methylbenzene …

GW-406381

GW-406381 has been used in trials studying the treatment of Pain, Trauma, Neurodynia, Dental Pain, and Hyperalgesia, among others.
Investigational
Matched Iupac: … 2-(4-ethoxyphenyl)-3-(4-methanesulfonylphenyl)pyrazolo[1,5-b]pyridazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pentetrazol

Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) receptor antagonist that was approved by the FDA until 1982.
Experimental
Withdrawn
Matched Iupac: … 5H,6H,7H,8H,9H-[1,2,3,4]tetrazolo[1,5-a]azepine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Emraclidine

Investigational
Matched Synonyms: … Ethanone, 1-(5,7-dihydro-2,4-dimethyl-6h-pyrrolo(3,4-b)pyridin-6-yl)-2-(1-(2-(trifluoromethyl)-4-pyridinyl …
Matched Iupac: … -yl}ethan-1-one ... 1-{2,4-dimethyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}-2-{1-[2-(trifluoromethyl)pyridin-4-yl]azetidin-3 …

Kaempherol

Experimental

GC-373

GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, GC-376 free acid[A219031,A219036]. It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription . GC-373 has been shown to inhibit the Mpro...
Experimental
Matched Iupac: … benzyl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-(2-oxopyrrolidin-3-yl)propan-2-yl]carbamoyl}butyl]carbamate …
Matched Description: … showed potent inhibition of the target, suggesting that GC-373 holds therapeutic potential for Covid-19 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Experimental Unapproved Treatments for COVID-19 …

Irosustat

Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Synonyms: … 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate …

(5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one

Experimental
Matched Name: … (5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one …
Matched Iupac: … (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(2-hydroxypropan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol …

(R)-Gossypol

(R)-Gossypol is the R-isomer of Gossypol.
Investigational
Matched Synonyms: … (r)-2,2'-bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) …

Cositecan

Cositecan is the novel camptothecin derivative which is also known as Karenitecin. It has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.
Investigational
Matched Iupac: … {4,9}.0^{15,20}]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione ... (19S)-19-ethyl-19-hydroxy-10-[2-(trimethylsilyl)ethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^ …

Rubitecan

Investigational
Matched Iupac: … -1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione ... (19S)-19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa …

CPP-115 free base

Investigational
Matched Synonyms: … (1s,3s)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid ... (+)-(1s,4s)-4-amino-3-(difluoromethylene)-1-cyclopentanecarboxylic acid …
Matched Iupac: … (1S,3S)-3-amino-4-(difluoromethylidene)cyclopentane-1-carboxylic acid …
Matched Salts cas: … 760947-97-5 …

LM-030

Investigational
Matched Synonyms: … (S)-2-ISOBUTYRYLAMINO-PENTANEDIOIC ACID 5-AMIDE 1-{[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-BIS-((S)-SEC-BUTYL ... )-21-HYDROXY-5-(4-HYDROXY-BENZYL)-15-ISOBUTYL-4,11-DIMETHYL-3,6,9,13,16,22-HEXAOXO-10-OXA-1,4,7,14,17 ... -.ALPHA.-((1S)-1-METHYLPROPYL)-2-OXO-1-PIPERIDINEACETYL-N-METHYL-L-TYROSYL-, (6->2)-LACTONE …
Matched Iupac: … (2S)-N-[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-bis[(2S)-butan-2-yl]-21-hydroxy-5-[(4-hydroxyphenyl)methyl …

(6S)-5,6,7,8-tetrahydrofolic acid

Experimental
Displaying drugs 3026 - 3050 of 8399 in total