Displaying drugs 3151 - 3175 of 3888 in total
Methylnaltrexone
Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL ... RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL) …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL ... RELISTOR (TM) (SUBCUTANEOUS INJECTION,12MG/0.6ML PER VIAL) …
Pembrolizumab
Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages ... [F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma ... as interchain bonds and 23 interchain bonds. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors …
Matched Products: … KEYTRUDA SOLUTION FOR INFUSION 25MG/ML ... Keytruda 100mg Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors …
Matched Products: … KEYTRUDA SOLUTION FOR INFUSION 25MG/ML ... Keytruda 100mg Solution for Infusion …
Faricimab
Retinal vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization (NV).[A225985, A225990, A225995] Vascular endothelial growth factor A (VEGF-A) is a well-known mediator of retinal NV, and many currently approved RVD therapies...
Approved
Investigational
Matched Description: … vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and ... and diabetic macular edema. ... retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … VABYSMO 6mg/0.05mL Solution for Intravitreal Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … VABYSMO 6mg/0.05mL Solution for Intravitreal Injection …
Spectinomycin
An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Matched Salts cas: … 22189-32-8 …
Matched Salts name: … Spectinomycin hydrochloride ... Spectinomycin hydrochloride pentahydrate …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TROBICIN FOR INJECTION 2 g/vial …
Matched Salts cas: … 22189-32-8 …
Matched Salts name: … Spectinomycin hydrochloride ... Spectinomycin hydrochloride pentahydrate …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TROBICIN FOR INJECTION 2 g/vial …
Dupilumab
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … atopic or allergic conditions, such as eczema, allergic reaction, and rhinosinusitis. ... cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several ... dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …
Ferric carboxymaltose
Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Approved
Matched Description: … Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. …
Matched Products: … Ferinject Solution for Injection 50mg/ml ... Ferinject® 50 mg iron/mL solution for injection/infusion …
Matched Products: … Ferinject Solution for Injection 50mg/ml ... Ferinject® 50 mg iron/mL solution for injection/infusion …
Sincalide
Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders. It is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as CCK-8. Naturally occurring cholecystokinin is a gastrointestinal peptide hormone normally essential for stimulating protein and fat digestion...
Approved
Matched Description: … It is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as _CCK- ... small bowel for cholesterol analysis, enzymatic activity analysis, and x-ray examination respectively ... Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Tests for Bile Duct Patency …
Matched Products: … Sincalide for Injection ... Kinevac Pws Inj 5mcg/vial …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Tests for Bile Duct Patency …
Matched Products: … Sincalide for Injection ... Kinevac Pws Inj 5mcg/vial …
Hepatitis B Vaccine (Recombinant)
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada.
The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … Certain population subgroups in these areas, however, are at high risk (see Indications and Clinical ... lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier ... There is no specific treatment for hepatitis. …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinfectives for Systemic Use ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Engerix-B 20 Adult Dose Suspension for Injection ... Engerix-B 10 Junior Dose Suspension for Injection ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinfectives for Systemic Use ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Engerix-B 20 Adult Dose Suspension for Injection ... Engerix-B 10 Junior Dose Suspension for Injection ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML …
Basiliximab
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell...
Approved
Investigational
Matched Description: … light chain constant region genes and mouse heavy and light chain variable region genes encoding the ... ) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and ... established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL ... SIMULECT FOR INJECTION 20 mg/vial …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL ... SIMULECT FOR INJECTION 20 mg/vial …
Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)
Approved
Matched Products: … IXIARO Suspension for Injection 0.5ml in pre-filled syringe …
Tagetitoxin
Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Cilofexor
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
SPH-3127
SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety of SPH3127 in Patients With Mild-moderate Essential Hypertension).
Investigational
Matched Synonyms: … CARBAMIC ACID, N-(3-(3-((1R)-1-(CYCLOPROPYL((2R)-2-MORPHOLINYLCARBONYL)AMINO)ETHYL)-6-METHYL-1H-PYRAZOLO …
Matched Description: … SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety …
Matched Description: … SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety …
4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
Experimental
Matched Name: … 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid …
Matched Iupac: … 4-[hydroxy(methyl)phosphoryl]-3-oxobutanoic acid …
Matched Iupac: … 4-[hydroxy(methyl)phosphoryl]-3-oxobutanoic acid …
(2s,3s)-Trans-2,3-Dihydro-3-Hydroxyanthranilic Acid
Experimental
Matched Name: … (2s,3s)-Trans-2,3-Dihydro-3-Hydroxyanthranilic Acid …
Matched Iupac: … (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid …
Matched Iupac: … (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid …
2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid
Experimental
Matched Name: … 2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid …
Matched Iupac: … 2-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}ethane-1-sulfonic acid …
Matched Iupac: … 2-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}ethane-1-sulfonic acid …
N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate …
Matched Iupac: … 1-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopropane-1-carboxylic acid …
Matched Iupac: … 1-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopropane-1-carboxylic acid …
2-Amino-4-(2-Amino-Ethoxy)-Butyric Acid
Experimental
Matched Name: … 2-Amino-4-(2-Amino-Ethoxy)-Butyric Acid …
Matched Iupac: … (2S)-2-amino-4-(2-aminoethoxy)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(2-aminoethoxy)butanoic acid …
5-Amino-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Experimental
Matched Name: … 5-Amino-3-Methyl-Pyrrolidine-2-Carboxylic Acid …
Matched Iupac: … (2R,3R,5R)-5-amino-3-methylpyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R,3R,5R)-5-amino-3-methylpyrrolidine-2-carboxylic acid …
1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
Experimental
Matched Name: … 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid …
Matched Iupac: … (2R,3R,4S)-2,4-dihydroxy-3-(sulfooxy)-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … (2R,3R,4S)-2,4-dihydroxy-3-(sulfooxy)-3,4-dihydro-2H-pyran-6-carboxylic acid …
6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid
Experimental
Matched Name: … 6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid …
Matched Iupac: … 6-(carboxyformamido)-1H-indole-5-carboxylic acid …
Matched Iupac: … 6-(carboxyformamido)-1H-indole-5-carboxylic acid …
4-{2-[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid
Experimental
Matched Name: … 4-{2-[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid …
Matched Iupac: … 4-[2-(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid …
Matched Iupac: … 4-[2-(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid …
2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid
Experimental
Matched Name: … 2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid …
Matched Iupac: … 2-{[3,5-dichloro-4-(hydroxyperoxy)phenyl]amino}benzoic acid …
Matched Iupac: … 2-{[3,5-dichloro-4-(hydroxyperoxy)phenyl]amino}benzoic acid …
PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE)
Experimental
Matched Name: … PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE) …
2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID
Experimental
Matched Name: … 2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID …
Matched Iupac: … 2-(2,6-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid …
Matched Iupac: … 2-(2,6-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid …
Displaying drugs 3151 - 3175 of 3888 in total