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Displaying drugs 3201 - 3225 of 3817 in total
Experimental
Matched Synonyms: … carboxymethylamino)-3-[(R)-hydroxy-(N-hydroxy-4-iodoanilino)methyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(R)-hydroxy[hydroxy(4-iodophenyl)amino]methyl]sulfanyl}ethyl]carbamoyl}butanoic acid
Experimental
Matched Synonyms: … N-[(S)-5-Amino-5-carboxypentyl]-L-glutamic acid
Matched Iupac: … (2S)-2-{[(5S)-5-amino-5-carboxypentyl]amino}pentanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Synonyms: … 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acid
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … Pfizer as Geocillin. ... Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by …
Matched Salts name: … Carbenicillin indanyl sodium
Matched Categories: … Sulfur Compounds …
NNC-55-0396 is a T-type Ca(2+) channel inhibitor.
Investigational
Matched Synonyms: … Cyclopropanecarboxylic acid, (1s,2s)-2-(2-((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro …
Matched Description: … NNC-55-0396 is a T-type Ca(2+) channel inhibitor.[A253047] …
Investigational
Matched Synonyms: … Coconut fatty acid diethanolamide …
TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Investigational
Matched Synonyms: … CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL …
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … 2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular …
Matched Mixtures name: … ARELIX ACE ... Apo-ramipril/hctz ... Apo-ramipril/hctz …
Matched Categories: … simvastatin, acetylsalicylic acid and ramipril ... atorvastatin, acetylsalicylic acid and ramipril ... Lipid Modifying Agents ... ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers …
Matched Products: … RAMIPRIL CORAX 5MG ... Ag-ramipril ... Act Ramipril …
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits ... the patient is undergoing a procedure to treat a blocked coronary artery. ... Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Drugs that are Mainly Renally Excreted ... Amino Acids, Cyclic …
Experimental
Matched Name: … (7as,12ar,12bs)-1,2,3,4,7a,12,12a,12b-Octahydroindolo[2,3-a]Quinolizin-7(6h)-One …
Matched Iupac: … (12bS)-1H,2H,3H,4H,6H,7H,12H,12bH-indolo[2,3-a]quinolizin-7-one …
Experimental
Matched Name: … N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine …
Matched Iupac: … N-cyclohexyl-4-{imidazo[1,2-a]pyridin-3-yl}-N-methylpyrimidin-2-amine …
Experimental
Matched Name: … 5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine …
Matched Iupac: … 5-(2,3-dichlorophenyl)-N-[(pyridin-4-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine …
Experimental
Matched Name: … 6-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine …
Matched Iupac: … 6-(2-fluorophenyl)-N-[(pyridin-3-yl)methyl]imidazo[1,2-a]pyrazin-8-amine …
Experimental
Matched Name: … 5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine …
Matched Iupac: … 5-(2-fluorophenyl)-N-[(pyridin-4-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine …
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched International brands: … AL ... ABZ ... Ben-A
Matched Synonyms: … (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Description: … A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … A-zole Suspension (Strawberry) 200mg/5ml …
Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.
Investigational
Matched Synonyms: … N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester …
Matched Description: … , and Normal Volunteers. ... Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Carbocyclic ... Carboxylic Acids
PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family.[A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin …
Matched Iupac: … 4-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic acid
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family ... [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine …
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid ... (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce ... Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Fatty Acids ... Fatty Acids, Unsaturated …
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid
Matched Description: … A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor …
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid
Matched Iupac: … 1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride ... Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. …
Matched Products: … Moxifloxacin Acino 400 mg Infusionslösung ... Avelox ABC Pack ... Ag-moxifloxacin …
Investigational
Matched Synonyms: … Acidic fibroblast growth factor ... Fibroblast growth factor, acidic ... Acidic fibroblast growth factor (aFGF) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN …
Matched Description: … [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ... with resistance mutation hotspots and targets mutations in the solvent-front region. ... resistance to multiple TKI has been reported, including [crizotinib], [lorlatinib], [taletrectinib], and
Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Synonyms: … alpha-Phylloquinone …
Matched Description: … [L33319] Phylloquinone has been synthesized since at least 1939,[A234384] and was approved by the ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates ... precursors to coagulation factors II, VII, IX, and X. …
Matched Mixtures name: … Vitamin D2 and K1 ... NUTRILITE CHILDREN MULTIVITAMIN AND IRON CHEWABLE TABLET …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Drugs that are Mainly Renally Excreted …
Matched Products: … KISAN INJECTION 1MG/ML (1ML AMP) …
Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Experimental
Matched Synonyms: … Cyclic adenylic acid ... Cyclic AMP ... 3',5'-cyclic AMP
Matched Description: … Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule ... that is important in many biological processes; it is derived from adenosine triphosphate (ATP). …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Cyclic AMP
Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid
Matched Description: … Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Synonyms: … β-glycerophosphoric acid calcium salt …
Matched Description: … The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... , and fillings. ... Calcium glycerophosphate is a [DB01373] salt of glycerophosphoric acid that forms a white, fine, slightly …
Matched Mixtures name: … Somarexin and C 1000 ... NUTROPLEX LIQUID WITH IRON AND LYSINE ... Alsimine W Vitamins A D …
Displaying drugs 3201 - 3225 of 3817 in total