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Displaying drugs 301 - 325 of 678 in total
Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …
GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid …
Matched Salts name: … Nalbuphine hydrochloride
Matched Products: … Nalbuphine Hydrochloride
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Description: … It has bactericidal activity and is used often as a topical disinfectant. ... A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout ... It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as …
Matched Mixtures name: … Lord and Berry ... Alcohol and Dextrose ... Alcohol and Dextrose …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Andys ... R and R ... Brompton and Langley Coconut Water and Habiscus Hand Sanitizer Coconut Water and Habiscus …
Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Matched Name: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …
Experimental
Matched Name: … Thiamine(1+) monophosphate …
Investigational
Matched Synonyms: … -4-yl]-4-methyl-1-oxopentan-2-yl]-4-[5-fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochloride
Amaranthus retroflexus pollen is the pollen of the Amaranthus retroflexus plant. Amaranthus retroflexus pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Pigweed, Rough Redroot Amaranthus retroflexus …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and
TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and
Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Salts name: … Guanfacine hydrochloride
Matched Products: … Guanfacine hydrochloride ... Guanfacine Hydrochloride
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 …
Matched Salts name: … Valaciclovir hydrochloride ... Valaciclovir hydrochloride monohydrate …
Matched Categories: … Acyclovir and prodrug ... Amino Acids, Peptides, and Proteins ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Valacyclovir Hydrochloride ... Valacyclovir hydrochloride ... VALACICLOVIR HYDROCHLORIDE
Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. …
Matched Salts name: … Selegiline hydrochloride
Matched Products: … Selegiline Hydrochloride
Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot...
Approved
Matched Iupac: … 5-[(2-chlorophenyl)methyl]-4H,5H,6H,7H-thieno[3,2-c]pyridine
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and ... agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine …
Matched Salts name: … Ticlopidine hydrochloride
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ticlopidine Hydrochloride ... Ticlopidine hydrochloride
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Approved
Matched Description: … , Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum. ... Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical ... treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum …
Matched Salts name: … Naftifine Hydrochloride
Matched Products: … Naftifine Hydrochloride ... Naftifine hydrochloride
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy …
Matched Mixtures name: … Benzocaine and Triclosan ... Benzocaine and Triclosan ... APRIL Bath and Shower Anti-bacterial Hand 3 Pack …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Raggedy Ann and Andy Cotton Candy ... Raggedy Ann and Andy Tropical Breeze ... Orchid Jasmine Tea and Basil …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … 3-(N-methylpyrollidino)pyridine ... (S)-3-(1-methylpyrrolidin-2-yl)pyridine ... 3-(2-(N-methylpyrrolidinyl))pyridine
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
Matched Description: … the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … Up and Up Nicotine ... Up and Up nicotine ... Berkley and Jensen Nicotine …
Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Short and Giant Ragweed Pollen Mix ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia …
Matched Products: … Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia …
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … various derivatives and have various functions. ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain ... Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride
Investigational
Matched Synonyms: … ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 ... Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and
Displaying drugs 301 - 325 of 678 in total