Displaying drugs 301 - 325 of 10844 in total
Protriptyline
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Synonyms: … 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine ... 7-(3-methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene …
Matched Description: … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission ... Protriptyline may be used for the treatment of depression. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Description: … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission ... Protriptyline may be used for the treatment of depression. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Osilodrostat
Osilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes the final step in the biosynthesis of endogenous cortisol. It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder in which cortisol levels are chronically and supraphysiologically elevated. Cushing's...
Approved
Investigational
Matched Description: … the final step in the biosynthesis of endogenous cortisol. ... [A191850] Osilodrostat was approved for use in the EU in January 2020 for the treatment of endogenous ... [L12123] It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder …
Pindolol
Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Description: … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s. ... Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. ... focused on the treatment of arrhythmia. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Description: … -2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma ... It is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the …
Sorghum halepense pollen
Sorghum halepense pollen is the pollen of the Sorghum halepense plant. Sorghum halepense pollen is mainly used in allergenic testing.
Approved
Matched Description: … Sorghum halepense pollen is mainly used in allergenic testing. ... Sorghum halepense pollen is the pollen of the Sorghum halepense plant. …
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Southern Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Southern Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Chlordiazepoxide
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Approved
Illicit
Investigational
Matched Synonyms: … 7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxide …
Matched Iupac: … 7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-4-ium-4-olate …
Matched Description: … It has also been used in the symptomatic treatment of alcohol withdrawal. …
Matched Iupac: … 7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-4-ium-4-olate …
Matched Description: … It has also been used in the symptomatic treatment of alcohol withdrawal. …
Bordetella pertussis toxoid antigen (formaldehyde inactivated)
Bordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine.
Approved
Matched Mixtures name: … -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …
Nebivolol
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure …
Calcipotriol
Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
Matched Description: … Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D. …
Technetium Tc-99m exametazime
Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease. Exametazime, also known as hexamethylpropyleneamine...
Approved
Matched Description: … detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. ... Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the ... It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Technetium Tc-99m succimer
Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA), is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma...
Approved
Matched Description: … A245643] is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in ... [L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first ... It works by binding to the cortical region of the kidneys. …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Isosulfan blue
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Migalastat
Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Description: … Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes ... alpha-Gal A for the treatment of Fabry disease in adults who have amenable GLA variants. ... Galafold, and the sponsor will be conducting a confirmatory clinical trial of Galafold in adults with …
Influenza A virus A/Brisbane/59/2007 (H1N1) hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Clavulanic acid
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … (Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of …
Vitamin A
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Description: … Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina ... Dietary vitamin A is derived from a variety of carotenoids found in plants. ... It is enriched in the liver, egg yolks, and the fat component of dairy products. …
Matched Categories: … Retinoids for Topical Use in Acne ... Compounds used in a research, industrial, or household setting …
Matched Products: … พี 7 แทปเลท …
Matched Categories: … Retinoids for Topical Use in Acne ... Compounds used in a research, industrial, or household setting …
Matched Products: … พี 7 แทปเลท …
Memantine
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … used in the management of Alzheimer's Disease (AD). ... Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability ... the management of Alzheimer's disease [A1639]. …
Matched Mixtures name: … EMAXIN BASLANGIC SETI, 7+7+7+7 ADET ... EMAXIN BASLANGIC SETI, 7+7+7+7 ADET ... EMAXIN BASLANGIC SETI, 7+7+7+7 ADET …
Matched Mixtures name: … EMAXIN BASLANGIC SETI, 7+7+7+7 ADET ... EMAXIN BASLANGIC SETI, 7+7+7+7 ADET ... EMAXIN BASLANGIC SETI, 7+7+7+7 ADET …
Pascopyrum smithii pollen
Pascopyrum smithii pollen is the pollen of the Pascopyrum smithii plant. Pascopyrum smithii pollen is mainly used in allergenic testing.
Approved
Matched Description: … Pascopyrum smithii pollen is mainly used in allergenic testing. ... Pascopyrum smithii pollen is the pollen of the Pascopyrum smithii plant. …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Description: … Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D ... Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby …
Oxygen
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt ... Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric ... Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing …
Matched Mixtures name: … Oxygen In Helium Mix ... Nitrous Oxide In Oxygen ... Oxygen In Helium Mixture …
Matched Mixtures name: … Oxygen In Helium Mix ... Nitrous Oxide In Oxygen ... Oxygen In Helium Mixture …
Larotrectinib
Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and...
Approved
Investigational
Matched Description: … both the induction of cellular apoptosis and the inhibition of cell growth in tumors that overexpress ... kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important ... of Trk-positive solid tumors. …
Methylphenidate
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … 6-7 hours. ... gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene that may be at least partly overcome ... [L6037] CADDRA recommends the use of methylphenidate due to long term studies, of over twenty years in …
Influenza B virus B/Massachusetts/2/2012 BX-51B hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Mixtures name: … FluVaccinol Subunit Tetra Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … FluVaccinol Subunit Tetra Injektionssuspension in einer Fertigspritze …
Displaying drugs 301 - 325 of 10844 in total