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Displaying drugs 301 - 325 of 2589 in total
Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … across various SCLC disease stages and treatment statuses. ... L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and ... delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Synonyms: … (+)-Pantothenic acid ... D-pantothenic acid
Matched Name: … Pantothenic acid
Matched Iupac: … 3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanoic acid
Matched Description: … Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog ... Pantothenic acid is an ingredient in some hair and skin care products. ... (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. …
Matched Mixtures name: … PNV Ferrous Fumarate Docusate Folic Acid ... Folivane-Plus with Ascorbic Acid Precursors ... B-complex With Vitamin C, Biotin, Folic Acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Blood Coagulation Factors ... Alimentary Tract and Metabolism ... Preparations for Treatment of Wounds and Ulcers …
Matched Products: … PANTOTHENIC ACID ... Pantothenic Acid ... Pantothenic Acid Tab 500mg …
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. …
Matched Mixtures name: … Facol Cold and Flu Night ... Facol Cold and Flu Day and Night ... Diphenhydramine HCl and Zinc Acetate …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Up and Up Nighttime Sleep-aid ... Berkley and Jensen Allergy …
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Description: … of [salicylic acid] linked to trivalent [bismuth cation]. ... Bismuth subsalicylate is an antacid and anti-diarrheal agent. ... to relieve nausea, diarrhea, and gastrointestinal discomfort. …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Up and Up 5-symptom Digestive Relief …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and
Matched Mixtures name: … Vitamins A and D Diaper Rash ... PETROLATUM and LANOLIN ... Blistex Revive and Restore …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Loratadine and Pseudoephedrine ... Allergy and Congestion Relief Non Drowsy ... Loratadine and Pseudoephedrine …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens Allergy Relief ... Berkley and Jensen Allergy Relief …
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Gentle and Effective Laxative Enteric Coated …
Ioxitalamate is an ionic iodinated contrast medium. It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg. Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. Until the...
Approved
Matched Synonyms: … Acide ioxitalamique ... Acido ioxitalamico ... Ioxitalamic acid
Matched Name: … Ioxitalamic acid
Matched Iupac: … 3-acetamido-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid
Matched Description: … [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem ... Canada Inc and approved by Health Canada in 1995. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... ioxitalamic acid ... Triiodobenzoic Acids
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Lice-Nil Lice and Eggs Killer ... Medi and Lice Lice Killing ... Weeks and Leo Complete Lice Treatment …
Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND ... ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Synonyms: … Cyanocobalamin ... Cyanocobalamine ... Cyanocobalaminum
Matched Name: … Cyanocobalamin
Matched Description: … to the fact that it contains the mineral, cobalt. ... This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular ... and nasal spray forms [FDA label], [L5542], [L5545]. …
Matched Mixtures name: … Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate ... PNV Ferrous Fumarate Docusate Folic Acid ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium …
Matched Categories: … Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid ... cyanocobalamin ... Blood and Blood Forming Organs ... Diet, Food, and Nutrition …
Matched Products: … Cyanocobalamin ... Cyancobalamin ... Cyanocobalamine
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... scrutinized for possible drug overdose and toxicity from accidental ingestion. …
Matched Mixtures name: … Redness reliever and Lubricant ... Up and Up Ultra Itchy Relief ... Seasonal itchy and Red eye relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops …
Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied . Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Description: … It is found in some laxatives for treating occasional constipation and restoring regularity in bowel …
Matched Categories: … Herbs and Natural Products …
Matched Products: … Up and Up Fiber Therapy ... up and up fiber therapy Natural Fiber ... Lidl Orange Smooth Fiber Powder Naturally and Artificially Flavored …
Iotroxic acid is a contrast medium molecule.
Experimental
Withdrawn
Matched Synonyms: … Acide iotroxique ... Acido iotroxico ... Iotroxic acid
Matched Name: … Iotroxic acid
Matched Iupac: … (2-{[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]methoxy}ethoxy)ethoxy]acetamido}-2,4,6-triiodobenzoic acid
Matched Description: … Iotroxic acid is a contrast medium molecule. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iotroxic acid ... Triiodobenzoic Acids
Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Synonyms: … Acide pamidronique ... Acido pamidronico ... Pamidronic acid
Matched Name: … Pamidronic acid
Matched Iupac: … (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
Matched Description: … ] and [alendronic acid]. ... ], [zoledronic acid], [minodronic acid], and [risedronic acid] are becoming more popular. ... Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... pamidronic acid
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … CLOTRIMAZOL ACIS 3 KOMBI ... CLOTRIMAZOL ACIS 3 KOMBI ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Kerasal foot and toe ... Protective Nail and skin ... Up and Up Jock Itch Relief …
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Synonyms: … Acide tiludronique ... Acido tiludronico ... Tiludronic acid
Matched Name: … Tiludronic acid
Matched Iupac: … {[(4-chlorophenyl)sulfanyl](phosphono)methyl}phosphonic acid
Matched Description: … ] and [clodronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... [A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763] …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... tiludronic acid
Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Experimental
Matched Synonyms: … Acide niflumique ... Acido niflumico ... Niflumic acid
Matched Name: … Niflumic acid
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid
Matched Description: … Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis …
Matched Categories: … Niflumic Acid and Prodrugs ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Acids, Carbocyclic …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Synonyms: … Acide risédroniqe ... Acido risedronico ... Risedronic acid
Matched Name: … Risedronic acid
Matched Iupac: … [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of …
Matched Categories: … risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential ... risedronic acid ... Calcium-Regulating Hormones and Agents …
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and ... invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and
N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. It is also used as conditioning for Bone marrow...
Approved
Investigational
Matched Description: … It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Immunologic Factors
Matched Products: … TEPADINA 400 mg powder and solvent for solution for infusion …
Displaying drugs 301 - 325 of 2589 in total