Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 301 - 325 of 9509 in total
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … of osteoporosis in postmenopausal women with the use of therapeutic agents in addition to concurrent ... [A716] Although rare, there was an increased risk of venous thromboembolism during clinical trials of ... Due to the risk of bone fractures that may lead to morbidities and reduced quality of life, the management …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Mixtures name: … TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADA ... TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADA …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … [L6748] Opioid overdoses kill an average of 11 Canadians daily. ... [A179542] Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or ... [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … ) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity ... Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6 ... On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for …
Rhodotorula rubra is a fungus which can provoke allergic reactions. Rhodotorula rubra is used in allergenic testing.
Approved
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol ... , thereby increasing membrane fluidity and preventing growth of the fungus. …
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … is the subject of many clinical trials in a variety of cancer types. ... of anticonvulsive activity. ... It is currently a compound of interest in the field of oncology for its anti-proliferative effects and …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … EPIGEL(R) CAPSULAS …
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Description: … [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. Other...
Approved
Investigational
Matched Description: … [L24474] It is an agonist of the melanocortin 4 receptor. ... [A224449] Patients taking setmelanotide experienced an average weight loss of 0.6 kg/week. …
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq …
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Description: … [A191068] It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Sulfaphenazole is a sulfonamide antibacterial.
Approved
Matched Categories: … combinations of sulfonamides …
Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors . Affecting about 1% of the...
Approved
Investigational
Matched Description: … schizophrenia resulted in improvement of positive and negative symptoms scores at day 85 of treatment ... for immediate initiation of Aristada at any dose. ... to achieve appropriate levels of aripiprazole more rapidly. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of ... indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of
Matched Categories: … Drugs for Treatment of Tuberculosis …
Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … signs of anxiety. ... Flupentixol is an antipsychotic drug of the thioxanthene group. ... by esterification of cis(Z)‐flupentixol with decanoic acid. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. ... certain natural substances that cause pain, nausea, and other symptoms of migraine. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Description: … over the course of 24 hours. ... Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease ... It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Rabbit allergenic extract is used in allergenic testing.
Approved
Investigational
Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...
Approved
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Matched Description: … Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. ... subsequently approved by the European Commission in April 2022 for both the treatment and prevention of ... [L41640] While several parenteral antagonists of CGRP and its receptor have been approved for migraine …
Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Mixtures name: … Plasma-Lyte R ... Normosol-R ... Normosol-R
Rhubarb allergenic extract is used in allergenic testing.
Approved
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … pending approval for the treatment of bipolar disorder in the United States. ... Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Description: … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of ... It is also used with pyrimethamine in the treatment of malaria. ... A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium …
Matched Categories: … Drugs for Treatment of Lepra …
Displaying drugs 301 - 325 of 9509 in total