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Displaying drugs 3226 - 3250 of 3971 in total
KB002 is an engineered human IgG1k antibody engineered human. It is developed for the treatment of autoimmune diseases, initially rheumatoid arthritis.
Investigational
Matched Description: … KB002 is an engineered human IgG1k antibody engineered human. …
1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. This compound belongs to the isoquinolines and derivatives. These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine. This medication is known to target mitogen-activated protein kinase 10.
Experimental
Matched Description: … This medication is known to target mitogen-activated protein kinase 10. …
Amediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase. [MeSH]
Investigational
Matched Description: … Amediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the …
Methyl undecenoyl leucinate is an active ingredient in whitening creams. It is an α-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes.
Experimental
Matched Iupac: … methyl (2S)-4-methyl-2-(undec-10-enamido)pentanoate …
Experimental
Matched Iupac: … 2-(9-oxo-9,10-dihydroacridin-10-yl)acetic acid …
Experimental
Matched Iupac: … 2-[2-(dimethylamino)ethoxy]ethyl 10H-phenothiazine-10-carboxylate …
Urapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
Investigational
Matched Products: … UPADİL 50 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... EBRASEL 50 MG/10 ML I.V. ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADET …
Malacidin A, along with DB14052, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin A...
Experimental
Matched Iupac: … (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl …
Matched Description: … Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis …
Malacidin B, along with DB14051, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin B...
Experimental
Matched Iupac: … (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl …
Matched Description: … Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis …
Dalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma).
Investigational
Matched Categories: … Recombinant Proteins …
SB-218078 is a specific inhibitor of CHK1.
Investigational
Experimental
IMT-288 is under investigation in clinical trial NCT01730638 (Immunotep for Patients With Medullary Thyroid Carcinoma.).
Investigational
MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human single chain variable fragment with affinity for human CD38 cell surface protein.
Investigational
Matched Description: … single chain variable fragment with affinity for human CD38 cell surface protein. ... 0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human
Component of human seminal plasma & spermatozoa.
Experimental
Matched Description: … Component of human seminal plasma & spermatozoa. …
SIG-001 is a cultured human retinal pigment epithelial cell line (ARPE-19) genetically modified with a non-viral vector to express B domain deleted human factor VIII protein, encapsulated within two-layer modified alginate spheres.
Investigational
Matched Description: … SIG-001 is a cultured human retinal pigment epithelial cell line (ARPE-19) genetically modified with ... a non-viral vector to express B domain deleted human factor VIII protein, encapsulated within two-layer …
Experimental
Matched Iupac: … 9-[(8-azaniumyloctyl)amino]-1,2,3,4-tetrahydroacridin-10-ium …
Experimental
Matched Iupac: … 10-[3-(dimethylamino)-2-methylpropyl]-10H-5lambda6-phenothiazine-5,5-dione …
UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria. Plasmepsins are aspartyl proteases produced by the malaria parasite Plasmodium falciparum, and PMX is considered to be essential for parasite egress and invasion. UCB7362 is estimated to achieve a significant reduction in asexual blood-stage...
Investigational
Matched Description: … ), _in vitro_ (_P. falciparum_ 3D7 lactate dehydrogenase growth inhibition assay IC50 = 10
Investigational
Matched Iupac: … 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl …
SIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified alginate spheres
Investigational
Matched Description: … vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified ... SIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral …
Displaying drugs 3226 - 3250 of 3971 in total