Displaying drugs 3376 - 3400 of 8033 in total
Gentamicin
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … [A234349] It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity ... against both gram-positive and gram-negative organisms but is particularly useful for the treatment of ... [A233325,A234359,A234364] There is the added benefit of synergy when gentamicin is co-administered with …
Neostigmine
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
Approved
Vet approved
Matched Description: … A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle …
Felbamate
Felbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak...
Approved
Matched Description: … Felbamate is an anticonvulsant drug used in the treatment of epilepsy. …
Mivacurium
Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Approved
Matched Description: … , resulting in a block of neuromuscular transmission. ... It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine …
Alverine
Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Approved
Investigational
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. …
Trioxsalen
Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of...
Approved
Matched Description: … Like other psoralens it causes photosensitization of the skin. ... light) for phototherapy treatment of vitiligo and hand eczema. ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage …
Lumateperone
Schizophrenia is a complex mental illness and impacts approximately 1% of the population. Although there are several antipsychotics including aripiprazole, paliperidone and clozapine available for clinical use, they are generally accompanied by significant metabolic and/or neurological adverse effects. Lumateperone is a newly approved 2nd generation antipsychotic currently indicated for the...
Approved
Investigational
Matched Description: … Schizophrenia is a complex mental illness and impacts approximately 1% of the population. ... Lumateperone is a newly approved 2nd generation antipsychotic currently indicated for the treatment of ... glutamate, serotonin and dopamine, which are all neurotransmitters that contribute to the pathophysiology of …
Spinosad
Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults. Spinosad is an insecticide based on a compound found in S. spinosa, a bacterial species....
Approved
Investigational
Vet approved
Matched Description: … ) used in the topical treatment of head lice in children (four years old and older) and in adults. ... Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively ... Spinosad has also been experimented for use in cats for treatment of flea infestations, and has also …
Foreskin keratinocyte (neonatal)
Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes. The keratinocytes form a...
Approved
Matched Description: … rates of wound healing and decreasing the time required for closure of wounds [L2452]. ... The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes ... It is composed of epidermal, dermal and hypodermal layers. …
Coccidioides immitis spherule
Coccidioides immitis spherule is a skin test antigen indicated to detect delayed-type hypersensitivity to Coccidioides immitis in individuals with a history of pulmonary coccidioidomycosis.
Approved
Matched Description: … indicated to detect delayed-type hypersensitivity to Coccidioides immitis in individuals with a history of …
Crotalus atrox antivenin
Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 .
Crotalus atrox antivenin...
Approved
Experimental
Matched Description: … The majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F113]. ... About 8000 of these snakebites involve venomous snake species. ... Bites from this snake are the most common in the state of Texas, USA [A33157]. …
Foslevodopa
Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Description: … 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's ... investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of …
DaxibotulinumtoxinA
DaxibotulinumtoxinA is an acetylcholine release inhibitor and neuromuscular blocking agent. It is a botulinum toxin without accessory proteins purified from the bacterium Clostridium botulinum type A, the gram-positive anaerobic bacterium primarily present in soil. C. botulinum is known to produce toxins that can cause botulism in humans.[A261075, L47860]
DaxibotulinumtoxinA was...
Approved
Matched Description: … [L47865] On August 14, 2023, the drug was also approved for the treatment of cervical dystonia. ... DaxibotulinumtoxinA was first approved by the FDA on September 8, 2022, for the temporary improvement of ... [L47870] DAXI or DAXXIFY, a product of daxibotulinumtoxinA, incorporates RTP004, a proprietary synthetic …
Hydroxyethyl Starch
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.
HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Polyestradiol phosphate
Polymeric phosphoric acid ester of estradiol.
Approved
Matched Description: … Polymeric phosphoric acid ester of estradiol. …
alpha-Tocopherol succinate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol ... Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... Moreover, manufacturers typically convert the phenol component of the vitamin to esters using acetic …
Interferon alfacon-1
Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the...
Approved
Investigational
Matched Description: … The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several ... This protein has a molecular weight of 19,434 daltons. ... at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of …
Pegvisomant
Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity.
Approved
Matched Description: … insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity. ... which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of …
Cidofovir
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Description: … It suppresses CMV replication through selective inhibition of viral DNA synthesis. ... Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis …
Deslanoside
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Approved
Matched Description: … A cardiotonic glycoside from the leaves of Digitalis lanata. …
Etidocaine
Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.
Approved
Matched Description: … Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during …
Influenza B virus B/Singapore/WUH4618/2021 antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Influenza A virus A/Delaware/55/2019 CVR-45 (H1N1) antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Influenza B virus B/Austria/1359417/2021 BVR-26 antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Displaying drugs 3376 - 3400 of 8033 in total