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Displaying drugs 326 - 350 of 15549 in total
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Synonyms: … 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine …
Matched Iupac: … 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),5,8,10,12 …
Matched Description: … due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility ... [T554] It was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996. ... Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent …
Matched Mixtures name: … TARGET 3 MG /25 MG KAPSUL, 90 ADET ... TARGET 3 MG /25 MG KAPSUL, 30 ADET ... FLUXOPIN 3 MG/25 MG KAPSÜL ,30 KAPSÜL …
Matched Products: … Olanzapine for Injection …
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea ... N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Description: … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257] ... Torasemide is a high-ceiling loop diuretic. ... [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … In December 2013, the G8 dementia summit concluded that dementia should be considered a global priority ... Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability ... with the objective of developing a cure or a disease-modifying therapy by the year 2025 [L5953, F4366 …
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Synonyms: … 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one ... 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one ... 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one …
Matched Description: … Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. ... for an extended period. ... [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as …
Matched Salts cas: … 124-90-3 ... 124133-68-2
Matched Mixtures name: … OSSICODONE E NALOXONE EG ... OSSICODONE E NALOXONE EG ... OSSICODONE E NALOXONE EG …
Matched Products: … OSSICODONE E NALOXONE EG ... Oxynorm 10mg/ml Solution for Injection or Infusion ... Sterile Solution for Injection or Infusion 10mg/ml …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Name: … Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...
Approved
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo …
Matched Description: … These two compounds are differentiated in the position of a methyl group. ... Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. ... This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine …
Streptococcus pneumoniae type 23f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 23f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 23f capsular polysaccharide antigen is a vaccine that contains highly purified ... It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche ... PREVENAR 13 SUSPENSION FOR INJECTION …
A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Synonyms: … 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. ... It has been shown in some cases to be more potent than diazepam or nitrazepam. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ESTA-2 ... ELGRAN-2
Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Description: … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles ... Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside for Injection ... Sodium Nitroprusside In 0.9% Sodium Chloride ... NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE …
Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Synonyms: … (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide …
Matched Iupac: … (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide …
Matched Description: … The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients ... It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Approved
Matched Synonyms: … 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt …
Matched Name: … Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) …
Matched Iupac: … sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …
Phycomyces blakesleeanus is a fungus which can provoke allergic reactions. Phycomyces blakesleeanus extract is used in allergenic testing.
Approved
Matched Description: … Phycomyces blakesleeanus extract is used in allergenic testing. ... Phycomyces blakesleeanus is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … C Mold Mixture ... C Mold Mixture ... C Mold Mixture …
Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Synonyms: … Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2- …
Matched Iupac: … (2-{[(3S,4E,6S,7E,9S,11R,15S,16E,18S,20R,21R,22E,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl …
Matched Description: … [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and ... Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... invasive candidiasis in adults with limited or no alternative treatment options. …
Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Iupac: … (4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-(2-{2-[2-(2-{[(2S)-1-[(2S)-2-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl ... ]-4-{[(2S,3S)-1-[(2S)-2-{[(1S)-3-carboxy-1-{[(1S)-3-carboxy-1-{[(1S)-1-{[(1S)-1-carboxy-3-methylbutyl ... acetamido}acetamido)-3-carbamoylpropanamido]acetamido}-3-carboxypropanamido]-3-phenylpropanamido]-4-carboxybutanamido ... ]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}propyl]carbamoyl}propyl]carbamoyl}pyrrolidin-1-yl]-3-methyl ... ]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}acetamido)acetamido] …
Matched Description: … Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin ... Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the ... Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial …
Matched Products: … Bivalirudin for Injection ... Bivalirudin in 0.9% Sodium Chloride ... ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML) …
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Synonyms: … 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylester …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar ... , along with other dihydropyridines, in 1972. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension …
Matched Products: … ANHITEN-A ... DEPIN-E RETARD ... DEPIN-E RETARD TABLETS 20 mg …
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788 ... It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows ... It is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility …
Matched Mixtures name: … Visine ALL DAY COMFORT DRY EYE Relief ... Visine for Red Eye Cool ... Visine for Red Eye Workplace …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Approved
Investigational
Matched Synonyms: … (±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ... 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well. ... Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … OKACIN GOZ DAMLASI 3 MG/ML 5 ML …
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Synonyms: … 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene ... 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine ... 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-yl}propyl)amine …
Matched Description: … See toxicity section below for a complete listing of side effects. ... In depressed individuals, protriptyline exerts a positive effect on mood. ... Protriptyline may be used for the treatment of depression. …
Matched Categories: … Antidepressive Agents Indicated for Depression …
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia ... The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium ... , in buffer solutions, and in fertilizers and explosives. …
Matched Mixtures name: … HD-3A LIQUID CONCENTRATE (ACID) FOR BICARBONATE DIALYSIS ... DAXTELY F ... HYDRASOR F
Matched Products: … Potassium Chloride for Injection Concentrate, USP (2 Meq/ml) ... Kcl Solution A 20% ... CLORURO DE POTASIO 2 MEQ/ML …
Egg white allergenic extract is used in allergenic testing.
Approved
Matched Description: … Egg white allergenic extract is used in allergenic testing. …
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Synonyms: … adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate] …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl …
Matched Description: … in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency. ... A condensation product of riboflavin and adenosine diphosphate. ... (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Description: … It is a controlled substance (opium derivative) listed in the U.S. ... However, under the name diamorphine, heroin is a legal prescription drug in the United Kingdom. ... Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. …
Matched Categories: … Drugs Used in Opioid Dependence ... Drugs Used in Addictive Disorders …
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21 ... -2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid ... -decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2R)-3-carbamoyl ... -bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29 …
Matched Description: … Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive ... Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal ... [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Daptomycin in Sodium Chloride ... CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL …
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Synonyms: … 2-Propylvaleric Acid ... 2-propyl-pentanoic acid ... 2-Propylpentanoic Acid …
Matched Iupac: … 2-propylpentanoic acid …
Matched Description: … effects of khelline when he found that all of his samples, dissolved in valproic acid, exerted a similar ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... It is currently a compound of interest in the field of oncology for its anti-proliferative effects and …
Matched Mixtures name: … Depakine Chronosphere 50 mg Retardgranulat in Beuteln ... Depakine Chronosphere 50 mg Retardgranulat in Beuteln ... Depakine Chronosphere 250 mg Retardgranulat in Beuteln …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A3 Substrates with a Narrow Therapeutic Index ... UGT1A6 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... UGT2B7 Substrates with a Narrow Therapeutic Index …
Matched Products: … EPILIM CHRONO 500MG (OBLONG FILM C* ) ... ACIDO VALPROICO E SODIO VALPROATO EG ... ACIDO VALPROICO E SODIO VALPROATO RATIOPHARM …
Displaying drugs 326 - 350 of 15549 in total