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Displaying drugs 326 - 350 of 13806 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Matched Mixtures name: … Fluarix Tetra Influenza Vaccine …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido ... N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6 ... (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy …
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido ... ]-1-phenylbutan-2-yl]carbamate …
Matched Description: … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible ... for the effective management of HIV-1 infection. ... Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] …
Matched Salts cas: … 2281870-65-1 ... 635728-49-3 ... 1447721-06-3
Matched Mixtures name: … VIRONTAR N COMPRIMIDOS RECUBIERTOS …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, ... COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN ... EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED …
Matched Description: … in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group ... It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification ... Elapegademase is a PEGylated recombinant adenosine deaminase. …
Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.
Approved
Matched Synonyms: … Immunoglobulin G1 (mouse monoclonal IMMU-MN3 Fab' fragment gamma-chain anti-human NCA-90 granulocyte cell antigen
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A ... -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE ... -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- …
Matched Iupac: … oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl ... (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) ... ]-2-hydroxybutanamide …
Matched Description: … label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 ... Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A. ... amino group of the deoxystreptamine moiety of kanamycin A. …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … AMIKACINA B. BRAUN ... Amikacin B. Braun 5 mg/ml Infusionslösung ... Amikacin B. Braun 2,5 mg/ml Infusionslösung …
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine ... 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine ... N-(γ-dimethylaminopropyl)iminodibenzyl …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... In depressed individuals, imipramine exerts a positive effect on mood. ... Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Matched Products: … SILEDX-3
Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Synonyms: … 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine …
Matched Iupac: … 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative ... In depressed individuals, amoxapine exerts a positive effect on mood. …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched International brands: … OraDisc A
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting of a
Matched Description: … Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped ... red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, ... inducing the production of normal fetal hemoglobin (HbF),[A262696,A262701] including [hydroxyurea] - a
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaene …
Matched Mixtures name: … XL-3 VR ... XL-3 XTRA …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one …
Matched Iupac: … 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10- …
Matched Description: … analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. ... A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside …
Matched Salts cas: … 220988-26-1
Matched Mixtures name: … ZIMODINE N ® ... LAVUZID® N ... CIPLADUOVIR-N TABLETAS …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Approved
Investigational
Matched Synonyms: … Deferrioxamine B
Matched Iupac: … N-(5-aminopentyl)-N-hydroxy-N'-[5-(N-hydroxy-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propanamido)pentyl …
Matched Description: … It forms iron complexes and is used as a chelating agent, particularly in the mesylate form. …
Matched Salts cas: … 1950-39-6 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Synonyms: … Tiacumicin B
Matched Iupac: … -1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy}-4-hydroxy-5-methoxy-2-methyloxan-3-yl 3,5-dichloro ... methylpropanoyl)oxy]oxan-2-yl]oxy}-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo ... -2-ethyl-4,6-dihydroxybenzoate ... 3S,4S,5S,6R)-6-{[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-{[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-[(2- …
Matched Description: … [A190516] The FDA initially approved fidaxomicin in May 2011 for the treatment of _C. difficile_-associated ... [L11575] Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. ... Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by _Clostridioides …
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Iupac: … (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one …
Matched Description: … A six carbon compound related to glucose. ... Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic …
Matched Mixtures name: … Chelated Cal-mag(2:1)with Zn Vit.c and D ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 25 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 6 AMPUL …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … T B TIN-C ... Formula # 2 Pwr 15mg/g ... Vit.c With N-M.bioflav.rose Hips and Rutin …
Approved
Matched Name: … Influenza virus type A (H1N1) …
Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Approved
Matched Synonyms: … 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine ... 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine ... 5-(γ-dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}-2-methylpropyl)dimethylamine …
Matched Salts cas: … 25332-13-2
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … L-a-Amino-g-methylthiobutyric acid ... (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … It is a chelating agent for heavy metals. ... A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Numeta G 16 % E Emulsion zur Infusion ... AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Porcine recombinant factor VIII B-domain truncated ... Antihemophilic factor porcine, B-domain truncated recombinant ... RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 …
Matched Description: … In a global, prospective, controlled, multi-center Phase 2/3 open-label clinical trial, all patients ... B domain replaced with a twenty-four amino acid linker. ... Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor …
Approved
Matched Name: … Cyd dengue virus serotype 4 live (attenuated) antigen
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Synonyms: … 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine …
Matched Iupac: … 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),5,8,10,12 …
Matched Description: … Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent ... very closely resembles [clozapine] and only differs by two additional methyl groups and the absence of a
Matched Salts cas: … 491828-16-1 ... 783334-36-1
Matched Mixtures name: … TARGET 3 MG /25 MG KAPSUL, 90 ADET ... TARGET 3 MG /25 MG KAPSUL, 30 ADET ... FLUXOPIN 3 MG/25 MG KAPSÜL ,30 KAPSÜL …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … Cl-F-Ara-A ... (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol ... 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. ... Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... OCT2 Substrates with a Narrow Therapeutic Index ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index …
Matched Products: … FARABIN 1 MG/ ML SOLUCIÓNINYECTABLE ... CLOLAR 1 MG/ML SOLUCION CONCENTRADA PARA INFUSION ... CLOLAR® 1 MG/ML SOLUCION CONCENTRADA PARA INFUSION …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Synonyms: … (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone …
Matched Iupac: … 2-(4-hydroxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}-1-benzothiophen-6-ol …
Matched Description: … Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic ... from [estradiol], raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a ... However, it has a negligible effect on altering the development and progression of breast cancer itself …
Matched Products: … ULOS-H
Approved
Matched Name: … Influenza virus type A (H3N2) …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Brisbane/9/2014 antigen (formaldehyde inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Synonyms: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... Monomycin A ... (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl …
Matched Iupac: … -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl ... (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino ... ]oxy}-2-(hydroxymethyl)oxane-3,4-diol …
Matched Products: … GABROSIDIN 0.5 G ENJEKTABL FLAKON, 1 ADET …
Displaying drugs 326 - 350 of 13806 in total