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Displaying drugs 326 - 350 of 15504 in total

Belladonna

Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain DB00424, DB00747, and mostly, DB00572. These alkaloids are naturally-occurring muscarinic antagonists. DB00572 is a non-selective muscarinic antagonist that is mainly used as an adjunct for...
Approved
Experimental
Matched Description: … Its roots, leaves and fruits contain [DB00424], [DB00747], and mostly, [DB00572]. ... Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a ... severe anticholinergic syndrome, which is associated with both central and peripheral manifestations …
Matched Mixtures name: … Belladonna and Opium ... Belladonna and Opium ... Belladonna and Opium …

Droxidopa

Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a...
Approved
Investigational
Matched Description: … associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is the ... It is approved for use in Japan and is currently in trials in the U.S. ... The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated …
Matched Categories: … Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Amino Acids, Peptides, and Proteins …

Calcipotriol

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-octahydro …
Matched Mixtures name: … Calcipotriene and Betamethasone Dipropionate ... Calcipotriene and Betamethasone Dipropionate ... Calcipotriene and Betamethasone Dipropionate …
Matched Categories: … Vitamin D and Analogues ... Skin and Mucous Membrane Agents …

Zinc

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … A metallic element of atomic number 30 and atomic weight 65.38. ... important role in protein synthesis and in cell division. ... treatment regimens for these and other neurological disorders [A32465]. …
Matched Mixtures name: … Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Trace Minerals Et/and B12 Tab …
Matched Categories: … Diet, Food, and Nutrition ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Methylergometrine

A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Iupac: … (4R,7R)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1 …
Matched Categories: … Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin ... Genito Urinary System and Sex Hormones …

Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and …
Matched Mixtures name: … Hydralazine HCl and Hydrochlorothiazide ... Hydralazine HCl and Hydrochlorothiazide ... Hydralazine HCl and Hydrochlorothiazide …
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … Up and Up Antacid and Pain Relief ... Sodium Citrate and Citric Acid ... Effervescent Antacid and Pain Relief …
Matched Categories: … Alimentary Tract and Metabolism …

Vanadium

Approved
Experimental
Matched Mixtures name: … Chromium and Vanadium (combo) ... Revit Multi-vitamins and Minerals ... Multivitamins and Minerals for Men …
Matched Categories: … Diet, Food, and Nutrition …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant ... Selenium is an essential trace element and antioxidant. …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multivitamins and Minerals Tablets ... Golf Vitamin and Mineral Supplement …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Isradipine

Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. Isradipine binds to calcium channels with high affinity and specificity...
Approved
Investigational
Matched Iupac: … 3-methyl 5-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Isradipine binds to calcium channels with high affinity and specificity and inhibits calcium flux into ... It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel ... cardiac and arterial smooth muscle cells. …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Imipenem

Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Description: … gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. ... product with cilastatin and [relebactam] which was recently approved by the FDA. ... semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. ... Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo. …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... caffeine and sodium benzoate ... sodium benzoate and sodium phenylacetate ... Various Alimentary Tract and Metabolism Products …

Potassium

Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … dextrose and sodium chloride. ... [A186928] Many conditions and diseases interfere with normal body potassium balance, and underconsumption ... They are available in an assortment of tablet, injection, and other forms, depending on the setting and …
Matched Mixtures name: … CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Potassium and Iodine Tab ... Revit Multi-vitamins and Minerals …
Matched Categories: … mefruside and potassium ... clopamide and potassium ... clofenamide and potassium ... furosemide and potassium ... quinethazone and potassium …

Valproic acid

Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... It is currently a compound of interest in the field of oncology for its anti-proliferative effects and …

Butorphanol

A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Approved
Illicit
Vet approved
Matched Description: … A synthetic morphinan analgesic with narcotic antagonist action. …

Tafamidis

Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives developed by FoldRX. Tafamidis is structurally similar to diflusinal. Tafamidis was granted an EMA market authorisation on 16 November 2011 and FDA approval on 3 May 2019.
Approved
Investigational
Matched Description: … Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives[A27206] developed by FoldRX. ... [A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Description: … Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. …

Flavin mononucleotide

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Description: … It is the principal form in which RIBOFLAVIN is found in cells and tissues. …
Matched Mixtures name: … Multi Vitamin and Fluoride ... Somarexin and C 1000 ... Multi Vitamin and Fluoride …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …

Inositol

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … of corn kernels by precipitation and hydrolysis of crude phytate. ... These molecules have structural similarities to glucose and are involved in cellular signaling. ... Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract …
Matched Mixtures name: … Niacin 500 Mg and Inositol ... Maxine Vitamin and Mineral Supplement ... Revit Multi-vitamins and Minerals …
Matched Categories: … Alimentary Tract and Metabolism …

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Iupac: … 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile …
Matched Description: … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Mixtures name: … Alogliptin and Pioglitazone ... Alogliptin and Pioglitazone ... Alogliptin and Pioglitazone …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and alogliptin ... pioglitazone and alogliptin ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog ... metabolize proteins, carbohydrates, and fats. ... , the provitamin panthenol, and as calcium pantothenate. …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Preparations for Treatment of Wounds and Ulcers …

Canis lupus familiaris dander

Canis lupus familiaris dander is the dander of Canis lupus familiaris. Canis lupus familiaris dander is used in allergenic testing.
Approved
Matched Mixtures name: … Animal Allergens, AP Dog Hair and Dander Canis spp ... Animal Allergens, Dog Hair and Dander Canis spp. ... Animal Allergens, Dog Hair and Dander Canis spp. …

Molybdenum

Molybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. Molybdenum is commonly used in metallurgy and other chemical applications however it has essential biological roles in...
Approved
Matched Description: … roles in organisms and microorganisms. ... Molybdenum is a chemical element with symbol Mo and atomic number 42. ... It is an essential trace dietary element and acts as a critical cofactor in several molybdenum-dependent …
Matched Mixtures name: … Revit Multi-vitamins and Minerals ... Multivitamins and Minerals for Men ... Formula Im-vitamins and Minerals Tab …
Matched Categories: … Diet, Food, and Nutrition …

Vitamin A

Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... It is enriched in the liver, egg yolks, and the fat component of dairy products. ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina …
Matched Mixtures name: … Vitamin A and D ... A and D Ointment ... Calci A and D Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Displaying drugs 326 - 350 of 15504 in total