Displaying drugs 3476 - 3500 of 8030 in total
Cefazolin
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Description: … A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Buserelin
Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR). It is used in prostate cancer treatment.
Approved
Investigational
Matched Description: … Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, …
Ceruletide
Caerulein is a specific decapeptide similar in action and composition to the natural gastrointestinal peptide hormone cholecystokinin. It exerts stimulatory effects on the gastric, biliary, and pancreatic secretion, as well as on certain smooth muscles.
Approved
Dabigatran
Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate.
Approved
Investigational
Matched Description: … Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate]. …
Omacetaxine mepesuccinate
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Description: … Then in March 2006, it received Orphan Drug status from the FDA for the treatment of CML. ... Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of ... October 2005, omacetaxine mepesuccinate received Orphan Drug designation from the EMEA for the treatment of …
Dobutamine
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Iodoform
Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions . Due to its antimicrobial properties following topical administration, minimal levels of iodoform may be found in disinfectants and it is more...
Approved
Experimental
Vet approved
Matched Description: … Due to its antimicrobial properties following topical administration, minimal levels of iodoform may ... Since the beginning of the 20th century, iodoform has been commonly used as a healing and antiseptic ... Iodoform is soluble in fatty acids and decomposes releasing iodine in nascent state (96,7% of iodine) …
Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine
The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19. It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with...
Approved
Matched Description: … speed and ease of manufacturing and increased immunogenicity. ... [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion ... developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of …
Tobramycin
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … Aminoglycosides, many of which are derived directly from _Streptomyces_ spp., are concentration-dependent ... L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of ... bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms …
Tirofiban
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Description: … Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while ... It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Lanolin
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments .
Lanolin is the purified, secreted...
Approved
Matched Description: … The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included ... Lanolin is the purified, secreted product of the sheep sebaceous glands [L2584]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. …
Methylprednisolone hemisuccinate
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Clevidipine
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Approved
Investigational
Pancrelipase amylase
Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The amylases are enzymes that help in the chemical process of digestion by hydrolizing starch into more available saccharide forms. The pancrelipase amylase is a...
Approved
Matched Description: … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases ... [L2509] The amylases are enzymes that help in the chemical process of digestion by hydrolizing starch …
Podophyllin
Podophyllin is a resin extracted from the roots of Podophyllum peltatum (American mandrake) and Podophyllum emodi, which contains numerous compounds, amongst which is podophyllin (as well as the drug podophyllotoxin). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Approved
Matched Description: … Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum …
Domiphen
Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Approved
Experimental
Neuropeptide Y
Neuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus.
Approved
Investigational
Matched Description: … Neuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus. …
Ramucirumab
Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability,...
Approved
Investigational
Matched Description: … By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby ... other agents directed against VEGFR-2, ramucirumab binds a specific epitope on the extracellular domain of ... VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of …
Amphotericin B
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Description: … Amphotericin B shows a high order of in vitro activity against many species of fungi. ... , Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of …
Copper
Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. Copper is commonly used in contraceptive intrauterine devices (IUD) .
Approved
Investigational
Matched Description: … It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and …
Bithionol
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Description: … Register of October 31, 1967 (32 FR 15046)). ... Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal …
Isoxaflutole
Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder.
Approved
Experimental
Investigational
Matched Description: … Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder …
Casirivimab
Casirivimab is a monoclonal antibody combined with Imdevimab in Regeneron's antibody cocktail known as REGN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … antibody combined with [Imdevimab] in Regeneron's antibody cocktail known as REGN-COV2 for the treatment of ... [L23539] This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition ... [A221495]
On November 21 2020, the FDA authorized emergency approval of REGEN-COV2 to treat mild …
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Description: … The glycine amide of 4-aminobenzoic acid. …
Displaying drugs 3476 - 3500 of 8030 in total