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Displaying drugs 351 - 375 of 10872 in total

Sodium acetate

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Description: … Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in ... It can be used also in metabolic acidosis and for urine alkalinization. ... It is mainly indicated to correct sodium levels in hyponatremic patients. …
Matched Mixtures name: … Isolyte M in Dextrose ... Isolyte H in Dextrose ... Isolyte P in Dextrose …

Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …

Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …

Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Mixtures name: … Afluria Tetra Injektionssuspension in einer Fertigspritze …

Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Mixtures name: … INFLUVAC TETRA, SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 ML …

Belzutifan

Belzutifan is an inhibitor of hypoxia-inducible factor 2α (HIF-2α) used in the treatment of von Hippel-Lindau (VHL) disease-associated cancers. The HIF-2α protein was first identified in the 1990s by researchers at UT Southwestern Medical Center as a key player in the growth of certain cancers. Initially considered to be undruggable,...
Approved
Investigational
Matched Iupac: … 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile …
Matched Description: … Belzutifan received FDA approval for the treatment of select VHL-associated cancers on August 13, 2021 ... Center as a key player in the growth of certain cancers. ... Belzutifan is an inhibitor of hypoxia-inducible factor 2α (HIF-2α) used in the treatment of von Hippel-Lindau …

Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … None of these varieties are available in the United States. ... It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …

Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Mixtures name: … Fluarix Tetra Injektionssuspension in einer Fertigspritze …

Parthenolide

Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,7E,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0^{2,4}]tetradec-7-en-13-one …
Matched Description: … Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. …

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Iupac: … 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14 …
Matched Description: … An antipsychotic agent used in schizophrenia. [PubChem] …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Colchicine

Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events....
Approved
Matched Iupac: … N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0^{2,7}]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl …
Matched Description: … [L8192] Colchicine is used in the treatment of gout flares and Familial Mediterranean fever,[L8138] and ... prevention of major cardiovascular events. ... [A183611] Its use was first approved by the FDA in 1961. …

Haemagglutinin-strain B (Victoria-like)

Approved
Matched Mixtures name: … Afluria Tetra Injektionssuspension in einer Fertigspritze …

Influenza B virus B/Washington/02/2019 recombinant hemagglutinin antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Mixtures name: … Fluarix Tetra Injektionssuspension in einer Fertigspritze …

Rilonacept

Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein ... syndromes, including familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells Syndrome (MWS), in …

Oxyquinoline

Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Matched Description: … Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and ... It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products. …
Matched Mixtures name: … INDIO (111-IN) OSSINA CURIUM NETHERLANDS …

Tolazamide

A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …
Matched Categories: … Drugs Used in Diabetes ... combinations of sulfonamides …

Mechlorethamine

A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. The FDA granted marketing approval for the orphan...
Approved
Investigational
Matched Description: … Each tube of Valchlor contains 0.016% of mechlorethamine which is equivalent to 0.02% mechlorethamine ... The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. ... stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL) in patients who have received …
Matched Salts cas: … 55-86-7 …
Matched Categories: … Weapons of Mass Destruction ... Compounds used in a research, industrial, or household setting …

Iohexol

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. ... Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …

Human thrombin

Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass...
Approved
Matched Description: … Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen ... In particular, while human thrombin products are made from pooled human source plasma, recombinant thrombin ... thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of …

Sacituzumab govitecan

Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2...
Approved
Investigational
Matched Description: … advance in cancer treatment. ... [A193653] In November 2021 and July 20 2023, sacituzumab govitecan was also approved by the European ... Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited …

Phenazopyridine

Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Description: … [L7832] It is still used in various parts of the world. ... In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. ... Ingestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or …
Matched Mixtures name: … All-In-One UTI Emergency Kit …

Tazobactam

Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Description: … mortality in hospitalized patients. ... Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other ... It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections …
Matched Mixtures name: … Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers ... Zosyn in Galaxy Containers …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant ... Cimetidine has a range of pharmacological actions. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … Cimetidine in Sodium Chloride …

Treprostinil

Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Description: … The first generic form of treprostinil became available in 2019.[A248775] ... Treprostinil was approved by the FDA in 2002 for the treatment of pulmonary arterial hypertension. ... [L41860] It is available in the following routes of administration: subcutaneous, intravenous, inhaled …

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. ... [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat ... [A1573,A257614,L45231] However, one of the major side effects of doxorubicin is cardiotoxicity, which …
Displaying drugs 351 - 375 of 10872 in total