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Displaying drugs 376 - 400 of 5920 in total
Approved
Vet approved
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Terra-Cortril ... Actinac Pws ... Actinac Pwr
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inducers ... Cytochrome P-450 CYP3A Inducers …
Matched Products: … American Safety and First Aid ... Cortiment-40 Sup 40mg ... HIPOKORT %0.5 KREM 30 G …
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Synonyms: … Clobetasol propionate ... clobetasol 17-propanoate ... Clobetasol propionate E …
Matched Name: … Clobetasol propionate
Matched Iupac: … 2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate ... (1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-1-(2-chloroacetyl)-9b-fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, …
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described ... [A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809] ... Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors …
Matched Mixtures name: … Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. ... Clobetasol Propionate 0.05% / Niacinamide 4% ... Clobetasol Propionate 0.05% / Niacinamide 4% …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … Clobetasol Propionate ANDA ... PMS-clobetasol ... PMS-clobetasol Cream …
Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Investigational
Matched Synonyms: … STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and
Matched Description: … primate STEAP1 and CD3. ... Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman …
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Iupac: … 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38 ... -decaen-1-yl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative ... [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant …
Matched Mixtures name: … PROTECT IRON Liquid ... Essential Pro ALPHA-G Q10 Capsule ... Vitamin E and Coq10 …
Matched Categories: … Diet, Food, and Nutrition ... Enzymes and Coenzymes ... P-glycoprotein substrates …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids ... SIF XZ 4 ... Cellsparc 360
Sulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric...
Approved
Matched Synonyms: … Sulfur fluoride ... sulfur(6+) fluoride ... sulfur(VI) fluoride
Matched Description: … ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and ... echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and
Matched Categories: … Ions ... Fluorides ... Fluorine Compounds …
Experimental
Matched Synonyms: … 1-Hexadecanesulfonyl fluoride ... Hexadecane-1-sulfonyl fluoride
Matched Name: … Hexadecanesulfonyl fluoride
Matched Iupac: … hexadecane-1-sulfonyl fluoride
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy ... (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy ... N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido …
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] …
Matched Salts cas: … 635728-49-3 ... 1447721-06-3
Matched Mixtures name: … REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … darunavir and cobicistat ... darunavir and ritonavir ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat …
Matched Products: … Darunavir 600 and 800 mg ... Pat-darunavir ... ดารุเวียร์-400
Experimental
Investigational
Matched Synonyms: … 4-(2-(aminomethyl)-1,3-thiazol-4-yl)-2,6-di(tert-butyl)phenol ... Phenol, 4-(2-(aminomethyl)-4-thiazolyl)-2,6-bis(1,1-dimethylethyl)- …
Matched Iupac: … 4-[2-(aminomethyl)-1,3-thiazol-4-yl]-2,6-di-tert-butylphenol …
Matched Salts cas: … 918656-59-4
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … 2',3'-Dideoxy-3'-thiacytidine ... 3'-Thia-2',3'-dideoxycytidine ... 3TC
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon ... It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). …
Matched Mixtures name: … LAMIVUDIN/ZID PUR 150/300 ... FAXIBON ® 40 ... CIPLABUDINAES 40
Matched Categories: … P-glycoprotein substrates ... lamivudine and abacavir ... stavudine and lamivudine ... zidovudine and lamivudine ... lamivudine and dolutegravir …
Matched Products: … Lamivudine and Zidovudine ... LAMIVUDIN TEVA PH BV 150MG ... 3tc
Izuralimab is under investigation in clinical trial NCT05879185 (A Study of Xmab23104 in People With Sarcoma).
Investigational
Matched Synonyms: … INDUCIBLE T-CELL COSTIMULATORY, ACTIVATION-INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE, AILIM, CD278)) AND ... ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), M …
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Synonyms: … N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine ... 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine …
Matched Description: … and reducing cough. ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing ... It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many …
Matched Mixtures name: … BROMIXEN ... BODREX FLU & BATUK BERDAHAK PE
Matched Categories: … Cough and Cold Preparations …
Matched Products: … HUSTAB P ... BROMXINE ELIXIR 4 mg/5 ml ... BROMXINE
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Synonyms: … [2-(2,6-dichloroanilino)phenyl]acetic acid …
Matched Iupac: … 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid …
Matched Description: … PGs contribute to inflammation and pain signalling. ... [A180796] The addition of two chlorine groups in the ortho position of the phenyl ring locks the ring ... (PGs). …
Matched Salts cas: … 119623-66-4
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac sodium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... diclofenac and antiinfectives ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 4% ... DICLOFENAC RATIO 50MG DISP
Experimental
Matched Synonyms: … Chloride ions ... Chloride (ion) ... Chloride
Matched Name: … Chloride ion
Matched Iupac: … chloride
Matched Mixtures name: … BION 3 FILM COATED TABLET ... POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 100 ML (PVC TORBA) SETLI ... POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 150 ML (PVC TORBA) SETLI …
Matched Categories: … Ions ... Chlorides ... Chlorine Compounds …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and
Matched Mixtures name: … MERDEX DUO %5 + %0.25 TOPIKAL JEL, 30 G ... SEMPTAL DUO %5 + %0.25 TOPIKAL JEL, 30 G ... USYEX %0,25/%0,12 SPREY, COZELTI 30 ML …
Matched Salts name: … Flurbiprofen sodium
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Propionates ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg ... Flurbiprofen Sodium ... ACUSTOP CATAPLASMA PLASTER 40 mg/sheet …
Englumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/refractory B-cell Non-hodgkin's Lymphoma).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa anti-(human B-lymphocyte antigen CD19) modified heterodimer where the heavy and ... fusion protein with immunoglobulin G1 [497-ala ... 71-248-4-1BB ligand (human precursor) fusion protein with peptide linker (GGGGS)2 fusion protein with …
Matched Description: … under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and ... Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination ... With Glofitamab Following a Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/refractory …
Propionate ion is under investigation in clinical trial NCT00846326 (Preventing Tolerance to Oxymetazoline in Allergic Rhinitis).
Investigational
Matched Synonyms: … Propanoate ion ... Propionate ... Propanoic acid, ion(1-) …
Matched Name: … Propionate ion
Matched Description: … Propionate ion is under investigation in clinical trial NCT00846326 (Preventing Tolerance to Oxymetazoline …
Omfiloctocog alfa is under investigation in clinical trial NCT03947567 (Safety and Efficacy of Long-term Treatment With SCT800 in Previously Treated Hemophilia a Patients.).
Investigational
Matched Synonyms: … 1639)-SEQUENCE: SINGLE-CHAIN RECOMBINANT FVIII COMPOSED OF DOMAINS A1-A1-A2-A2 (1-740), THE B-DOMAIN N-AND
Matched Description: … Omfiloctocog alfa is under investigation in clinical trial NCT03947567 (Safety and Efficacy of Long-term
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-8-one …
Matched Description: … Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief ... PMS-ketotifen ... Leader Allergy Eye …
Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational
Matched Synonyms: … Copper chloride ... Copper(2+) chloride ... copper(II) chloride
Matched Name: … Cupric Chloride
Matched Description: … Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to …
Matched Salts name: … Cupric chloride dihydrate …
Matched Products: … Copper ... Cupric Chloride
Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE ... RECEPTOR VARIANT III) (HUMAN MONOCLONAL EGFRVIII BISPECIFIC 1 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3- …
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 ... N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Iupac: … N-{6-[3-tert-butyl-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Description: … SVR and eradication of HCV infection is associated with significant long-term health benefits including ... Pak have been shown to achieve a SVR of 100% for genotype 1b and 89% or 95% for genotype 1a after 12 ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and
Matched Salts cas: … 1132940-11-4
Matched Mixtures name: … Viekira Pak ... Holkira Pak ... VIEKIRA PAK TABLET …
Matched Salts name: … Dasabuvir sodium ... Dasabuvir sodium monohydrate …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates …
Methanesulfonyl Fluoride has been used in trials studying the treatment of Safety.
Investigational
Matched Name: … Methanesulfonyl Fluoride
Matched Iupac: … methanesulfonyl fluoride
Matched Description: … Methanesulfonyl Fluoride has been used in trials studying the treatment of Safety. …
Fluorine-18 is under investigation in clinical trial NCT00870974 (A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions).
Investigational
Matched Synonyms: … Fluorine-18 …
Matched Name: … Fluorine F-18 …
Matched Description: … Fluorine-18 is under investigation in clinical trial NCT00870974 (A PET Brain Imaging Study of mGluR5 …
Experimental
Matched Synonyms: … Iron(2+) ion ... Iron(II) ion ... Iron, ion (Fe2+) …
Matched Iupac: … lambda2-iron(2+) ion
Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). Thyroid hormones directly regulate lipid metabolism in the liver;...
Approved
Investigational
Matched Synonyms: … oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo- ... 2-[3,5-Dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro- ... 3,5-dioxo-1,2,4-triazine-6-carbonitrile …
Matched Iupac: … 2-(3,5-dichloro-4-{[6-oxo-5-(propan-2-yl)-1,6-dihydropyridazin-3-yl]oxy}phenyl)-3,5-dioxo-2,3,4,5-tetrahydro …
Matched Description: … [A263461] Resmetirom works to reduce liver fat by stimulating fatty acid degradation and oxidation. …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2C8 Inhibitors (weak) …
Displaying drugs 376 - 400 of 5920 in total