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Displaying drugs 376 - 400 of 15129 in total

Belladonna

Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain DB00424, DB00747, and mostly, DB00572. These alkaloids are naturally-occurring muscarinic antagonists. DB00572 is a non-selective muscarinic antagonist that is mainly used as an adjunct for...
Approved
Experimental
Matched Description: … Its roots, leaves and fruits contain [DB00424], [DB00747], and mostly, [DB00572]. ... Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a ... severe anticholinergic syndrome, which is associated with both central and peripheral manifestations …
Matched Mixtures name: … Belladonna and Opium ... Belladonna and Opium ... Belladonna and Opium …

Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and …
Matched Mixtures name: … Hydralazine HCl and Hydrochlorothiazide ... Hydralazine HCl and Hydrochlorothiazide ... Hydralazine HCl and Hydrochlorothiazide …
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …

Triclocarban

Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Description: … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products …

Xanthan gum

Xanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic acid. Xanthan gum is a direct food additive permitted for direct addition to food for human consumption by the FDA....
Approved
Matched Description: … The major constituents include D-glucose, D-mannose, and D-glucuronic acid. ... It is used as a thickening agent and stabilizer in emulsions. ... is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and …
Matched Categories: … Diet, Food, and Nutrition …

Chromium picolinate

Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. Chromium ions are shown to regulate...
Approved
Matched Description: … It is a coordination complex consisting of chromium(III) and picolinic acid. ... Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. ... Chromium ions are shown to regulate insulin by promoting glucose utilization and increasing the sensitivity …

Glucagon

Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Description: … Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit ... the movement of the gastrointestinal tract and to treat severe hypoglycemia. ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Ethanolamine oleate

Ethanolamine oleate is a mild sclerosing agent. It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.
Approved
Matched Iupac: … (9Z)-octadec-9-enoic acid; 2-aminoethan-1-ol …
Matched Description: … It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, …

Vanadium

Approved
Experimental
Matched Mixtures name: … Chromium and Vanadium (combo) ... Revit Multi-vitamins and Minerals ... Multivitamins and Minerals for Men …
Matched Categories: … Diet, Food, and Nutrition …

Ketazolam

Ketazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. Ketazolam is not approved in Canada or America.
Approved
Matched Description: … Ketazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol ... ,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and ... during the postpartum period, and this should be considered when assessing potential risks of hormonal …
Matched Mixtures name: … Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol …
Matched Categories: … drospirenone and estetrol ... drospirenone and estrogen ... drospirenone and ethinylestradiol ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Adefovir dipivoxil

Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Matched Description: … Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …

Zalcitabine

A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …

Canis lupus familiaris dander

Canis lupus familiaris dander is the dander of Canis lupus familiaris. Canis lupus familiaris dander is used in allergenic testing.
Approved
Matched Mixtures name: … Animal Allergens, AP Dog Hair and Dander Canis spp ... Animal Allergens, Dog Hair and Dander Canis spp. ... Animal Allergens, Dog Hair and Dander Canis spp. …

Oxyquinoline

Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Matched Description: … Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and …
Matched Salts name: … 8-Hydroxyquinoline citrate …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment …

Safinamide

Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Approved
Investigational
Matched Description: … It was approved in Europe in February 2015, and in the United States on March 21, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Azelastine

Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Description: … vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis. ... phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and ... racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and …
Matched Mixtures name: … Azelastine hydrochloride and Fluticasone propionate ... Azelastine Hydrochloride and Fluticasone Propionate ... Azelastine Hydrochloride and Fluticasone Propionate …
Matched Categories: … Decongestants and Antiallergics …

Nilotinib

Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Description: … A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic …
Matched Salts name: … Nilotinib hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Isometheptene

Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Approved
Matched Description: … It is used for treating migraines and tension headaches. …
Matched Mixtures name: … Isometheptene Mucate, Caffeine, and Acetaminophen ... Isometheptene Mucate, Caffeine, and Acetaminophen ... Isometheptene Mucate, Caffeine, and Acetaminophen …
Matched Categories: … Alimentary Tract and Metabolism …

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Mixtures name: … Alogliptin and Pioglitazone ... Alogliptin and Pioglitazone ... Alogliptin and Pioglitazone …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and alogliptin ... pioglitazone and alogliptin ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Pefloxacin

A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Approved
Matched Iupac: … 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and …
Matched Salts name: … Pefloxacin mesylate dihydrate …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Reviparin

Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Description: … [A32019] It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. ... [A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …

Asparaginase Erwinia chrysanthemi

Asparaginase Erwinia chrysanthemi is an asparaginase-specific enzyme derived from Erwinia chrysanthemi used as an anticancer agent. It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death. L-asparaginase was first identified in...
Approved
Investigational
Matched Description: … It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA ... synthesis and cell survival of malignant cells, leading to cell death. ... [L1448] L-asparaginase was first identified in 1963,[A236344] and there are different formulations of …
Matched Categories: … Enzymes and Coenzymes …

Molybdenum

Molybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. Molybdenum is commonly used in metallurgy and other chemical applications however it has essential biological roles in...
Approved
Matched Description: … roles in organisms and microorganisms. ... Molybdenum is a chemical element with symbol Mo and atomic number 42. ... It is an essential trace dietary element and acts as a critical cofactor in several molybdenum-dependent …
Matched Mixtures name: … Revit Multi-vitamins and Minerals ... Multivitamins and Minerals for Men ... Formula Im-vitamins and Minerals Tab …
Matched Categories: … Diet, Food, and Nutrition …

Desonide

A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Categories: … desonide and antiseptics …

Cavia porcellus hair

Guinea pig hair is used in allergenic testing.
Approved
Matched Mixtures name: … Guinea Pig Hair and Epithelia ... Animal Allergens, Guinea Pig Hair and Dander ... Animal Allergens, Guinea Pig Hair and Dander …
Displaying drugs 376 - 400 of 15129 in total