Displaying drugs 401 - 425 of 2459 in total
Suratadenoturev
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … telomerase reverse transcriptase (hTERT) and IRES, respectively. ... -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Aminocaproic acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Synonyms: … 6-Aminocaproic acid ... Aminocaproic acid ... 6-aminohexanoic acid …
Matched Name: … Aminocaproic acid …
Matched Iupac: … 6-aminohexanoic acid …
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Aminocaproic Acid ... Aminocaproic acid …
Matched Name: … Aminocaproic acid …
Matched Iupac: … 6-aminohexanoic acid …
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Aminocaproic Acid ... Aminocaproic acid …
Hopantenic acid
Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome.
Experimental
Matched Synonyms: … Acide hopantenique ... Acido hopantenico ... Hopantenic acid …
Matched Name: … Hopantenic acid …
Matched Iupac: … 4-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]butanoic acid …
Matched Description: … Hopantenic acid (Pantogam) is a central nervous system depressant. ... Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Hopantenic acid …
Matched Iupac: … 4-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]butanoic acid …
Matched Description: … Hopantenic acid (Pantogam) is a central nervous system depressant. ... Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
AB-201
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
OTL-102
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …
Matched Description: … These are heat inactivated and purified. …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... apadamtase alfa and cinaxadamtase alfa …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... apadamtase alfa and cinaxadamtase alfa …
Mycophenolic acid
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Synonyms: … Acido micofenolico ... Mycophenolic acid ... Micofenolico acido …
Matched Name: … Mycophenolic acid …
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid …
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid …
Matched Name: … Mycophenolic acid …
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid …
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid …
Butylidenephthalide
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers …
Matched Categories: … Phthalic Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Categories: … Phthalic Acids ... Carboxylic Acids ... Acids, Carbocyclic …
OTL-203
OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Methylcellulose
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
Tolnaftate
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Synonyms: … m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester ... Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Up and Up Antifungal ... Fungi Nail Toe and Foot ... Up and Up Soothing Antifungal …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Up and Up Antifungal ... Fungi Nail Toe and Foot ... Up and Up Soothing Antifungal …
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and ... invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and …
Matched Description: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and ... invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and …
Omeprazole
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … characterized by the oversecretion of gastric acid. ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer …
Matched Products: … Acid Reducer ... Up and Up Omeprazole ... Berkley and Jensen Omeprazole …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer …
Matched Products: … Acid Reducer ... Up and Up Omeprazole ... Berkley and Jensen Omeprazole …
Tavokinogene telseplasmid
Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational
Matched Synonyms: … Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are ... separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus …
Azercabtagene zapreleucel
Investigational
Matched Synonyms: … Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporati ... Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor …
Ociperlimab
Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage III Unresectable Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(homo sapiens tigit (t-cell immunoreceptor with ig domain and itim, v-set ... ig member 9, vsig9, v-set and transmembrane member 3, vstm3)), humanized monoclonal antibody (ociperlimab …
Ergidina
Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …
Citric acid
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Acidum citricum ... Anhydrous citric acid ... Citric acid,anhydrous …
Matched Name: … Citric acid …
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid …
Matched Description: … It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids …
Matched Products: … Citric Acid ... Citric Acid Wipes …
Matched Name: … Citric acid …
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid …
Matched Description: … It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid …
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids …
Matched Products: … Citric Acid ... Citric Acid Wipes …
Tioconazole
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus …
Matched Categories: … Imidazole and Triazole Derivatives ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Up and up tioconazole 1 ... Foster and Thrive Tioconazole …
Matched Categories: … Imidazole and Triazole Derivatives ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Up and up tioconazole 1 ... Foster and Thrive Tioconazole …
Dichloroacetic acid
Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase. Early reports of its activity...
Approved
Investigational
Matched Synonyms: … Dichloracetic acid …
Matched Name: … Dichloroacetic acid …
Matched Iupac: … 2,2-dichloroacetic acid …
Matched Description: … and removal of a wide variety of skin and tissue lesions), but was cancelled post market. ... Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three ... DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Bichloracetic Acid 100% …
Matched Name: … Dichloroacetic acid …
Matched Iupac: … 2,2-dichloroacetic acid …
Matched Description: … and removal of a wide variety of skin and tissue lesions), but was cancelled post market. ... Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three ... DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Bichloracetic Acid 100% …
Chlorine
Chlorine is a stongly oxidizing agent and the third most electronegative element which belongs to the group of halogens with the atomic number 17 and symbol Cl. Being a yellow-green gas at room temperature, chlorine is the second most abundant halogen on Earth. It is commonly used in sanitation, disinfection...
Experimental
Matched Description: … group of halogens with the atomic number 17 and symbol Cl. ... It was also used in chemical warfare and in rocket fuel. ... It is commonly used in sanitation, disinfection and antiseptic processes. …
Matched Products: … Trichloroisocyanuric Acid …
Matched Products: … Trichloroisocyanuric Acid …
Leuprolide
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... leuprorelin and bicalutamide ... Antineoplastic and Immunomodulating Agents …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... leuprorelin and bicalutamide ... Antineoplastic and Immunomodulating Agents …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg …
Displaying drugs 401 - 425 of 2459 in total