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Displaying drugs 401 - 425 of 1251 in total
1-(1-phenylcyclopentyl)methylamine
Experimental
Matched Synonyms: … C-(1-Phenyl-cyclopentyl)-methylamine …
[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid
Experimental
Matched Name: … [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid …
Matched Iupac: … 2-[3,5-dibromo-4-(4-hydroxy-3-{hydroxy[(2-phenylethyl)amino]methyl}phenoxy)phenyl]ethane-1,1-diol …
Matched Iupac: … 2-[3,5-dibromo-4-(4-hydroxy-3-{hydroxy[(2-phenylethyl)amino]methyl}phenoxy)phenyl]ethane-1,1-diol …
CB-103
CB-103 is under investigation in clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies).
Investigational
Matched Synonyms: … 3-PYRIDINAMINE, 6-(4-(1,1-DIMETHYLETHYL)PHENOXY)- ... 6-(4-(1,1-Dimethylethyl)phenoxy)-3-pyridinamine …
Matched Description: … clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and …
Matched Description: … clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and …
Suprofen
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … 2-(4-(2-Thenoyl)phenyl)propionsäure ... (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
GBR-12879
Investigational
Matched Synonyms: … 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine ... Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)- ... Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propen-1-yl)- …
Fosgemcitabine palabenamide
NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … L-ALANINE, N-(2'-DEOXY-2',2'-DIFLUORO-P-PHENYL-5'-CYTIDYLYL)-, PHENYLMETHYL ESTER ... N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-L-alanine phenylmethyl ester ... L-Alanine, N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-, phenylmethyl ester …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
4-Phenyl-1h-Imidazole
Experimental
Matched Name: … 4-Phenyl-1h-Imidazole …
Matched Iupac: … 5-phenyl-1H-imidazole …
Matched Iupac: … 5-phenyl-1H-imidazole …
Ezogabine
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate ... N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester ... N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and …
Diethylpropion
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Synonyms: … 1-phenyl-2-diethylamino-1-propanone ... 2-(diethylamino)-1-phenyl-1-propanone …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Olopatadine
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Procyclidine
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Approved
Matched Synonyms: … 1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol ... 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride …
Matched Iupac: … 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
Matched Iupac: … 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
Cinnamic acid
Investigational
Matched Synonyms: … 2-propenoic acid, 3-phenyl- ... 3-phenyl-2-propenoic acid ... 2-propenoic acid, 3-phenyl-, (2e)- …
Matched Categories: … Heparin and similars …
Matched Categories: … Heparin and similars …
Biotin
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals ... Essential Vitamins and Minerals …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals ... Essential Vitamins and Minerals …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …
Cycrimine
Cycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.
Approved
Matched Synonyms: … alpha-cyclopentyl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and …
Matched Iupac: … 1-cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and …
Furaprofen
Investigational
Matched Synonyms: … alpha-Methyl-3-phenyl-7-benzofuranacetic acid …
Matched Iupac: … 2-(3-phenyl-1-benzofuran-7-yl)propanoic acid …
Matched Iupac: … 2-(3-phenyl-1-benzofuran-7-yl)propanoic acid …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and ... rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and ... rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
ANEB-001
ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB1 Antagonist ANEB-001 in a THC Challenge Test).
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, 3-((R)-(4-CHLOROPHENYL)(2-(TRIFLUOROMETHYL)PHENYL)METHOXY)-N-(1,1-DIMETHYLETHYL ... 3-((R)-(4-CHLOROPHENYL)(2-(TRIFLUOROMETHYL)PHENYL)METHOXY)-N-(1,1-DIMETHYLETHYL)-1-AZETIDINECARBOXAMIDE …
Matched Description: … ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and …
Matched Description: … ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and …
Esomeprazole
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis ... Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer. …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... naproxen and esomeprazole ... Antiinflammatory and Antirheumatic Products ... esomeprazole, amoxicillin and clarithromycin …
Matched Products: … Up and Up Esomeprazole Magnesium ... Foster and Thrive Acid Reducer ... Berkley and Jensen Heartburn Treatment …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... naproxen and esomeprazole ... Antiinflammatory and Antirheumatic Products ... esomeprazole, amoxicillin and clarithromycin …
Matched Products: … Up and Up Esomeprazole Magnesium ... Foster and Thrive Acid Reducer ... Berkley and Jensen Heartburn Treatment …
TG100-115
An NSAID that inhibits PI-3K gamma and delta.
Investigational
Matched Synonyms: … 3-(2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Pterostilbene
Investigational
Matched Synonyms: … PHENOL, 4-((1E)-2-(3,5-DIMETHOXYPHENYL)ETHENYL)- …
Matched Iupac: … 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol …
Matched Iupac: … 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol …
Lufenuron
Lufenuron is used in veterinary for the control of flea.
Experimental
Vet approved
Matched Synonyms: … 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea ... N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione ... 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … , Frisium, Urbanyl, and others. ... children aged two years and older. ... and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … , Frisium, Urbanyl, and others. ... children aged two years and older. ... and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Displaying drugs 401 - 425 of 1251 in total