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Displaying drugs 4251 - 4275 of 8652 in total
E1v1.11
E1v1.11 is an antisense oligonucleotide targeting the SMN2 gene which is under investigation for the treatment of spinal muscular atrophy (SMA).
Investigational
Matched Synonyms: … Phosphorodiamidate morpholino oligomer (5'- CTATATATAGTTATTCAACA -3') …
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine
Experimental
Matched Name: … N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine …
Matched Iupac: … (2S)-2-amino-5-(N'-hydroxycarbamimidamido)pentanoic acid …
Matched Iupac: … (2S)-2-amino-5-(N'-hydroxycarbamimidamido)pentanoic acid …
N,N-dimethylarginine
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a...
Experimental
Matched Synonyms: … N(5)-((Dimethylamino)iminomethyl)-L-ornithine …
Matched Iupac: … (2S)-2-amino-5-[(E)-[amino(dimethylamino)methylidene]amino]pentanoic acid …
Matched Iupac: … (2S)-2-amino-5-[(E)-[amino(dimethylamino)methylidene]amino]pentanoic acid …
Camoteskimab
Camoteskimab is under investigation in clinical trial NCT06436183 (A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis).
Investigational
Matched Synonyms: … phenylalanine,243-glutamic acid,339-serine), anti-(human interleukin 18) (human monoclonal cerc-007 .gamma.1- …
10-Propargyl-5,8-Dideazafolic Acid
Experimental
Matched Iupac: … (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}phenyl)formamido] …
OCTANE-1,3,5,7-TETRACARBOXYLIC ACID
Experimental
Matched Iupac: … (1S,3R,5R)-1-methylheptane-1,3,5,7-tetracarboxylic acid …
1-Methylhistidine
Experimental
Matched Synonyms: … 1-methyl-L-histidine ... (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Name: … 1-Methylhistidine …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Name: … 1-Methylhistidine …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Ivarmacitinib
Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the treatment of various immuno-inflammatory conditions. While ivarmactinib has yet to receive marketing authorization, as of February 2022 clinical trials are ongoing or completed evaluating its use in atopic dermatitis,[L40604,L40619,L40629] ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis,...
Experimental
Investigational
Matched Iupac: … (3aR,5S,6aS)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]-octahydrocyclopenta …
Matched Description: … Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the …
Matched Categories: … Janus Kinase 1, antagonists & inhibitors …
Matched Description: … Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the …
Matched Categories: … Janus Kinase 1, antagonists & inhibitors …
CY 1899
Investigational
Matched Synonyms: … L-Valine, N2,N6-bis(1-oxohexadecyl)-L-lysyl-L-seryl-L-seryl-L-glutaminyl-L-tyrosyl-L-isoleucyl-L-lysyl-L-alanyl-L-asparaginyl-L-seryl-L-lysyl-L-phenylalanyl-L-isoleucylglycyl-L-isoleucyl-L-threonyl-L …
N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane
Experimental
2,5-dibenzyloxy-3-hydroxy-hexanedioic acid bis-[(2-hydroxy-indan-1-yl)-amide]
Experimental
Matched Name: … 2,5-dibenzyloxy-3-hydroxy-hexanedioic acid bis-[(2-hydroxy-indan-1-yl)-amide] …
Matched Iupac: … (2R,3R,5R)-2,5-bis(benzyloxy)-3-hydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]hexanediamide …
Matched Iupac: … (2R,3R,5R)-2,5-bis(benzyloxy)-3-hydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]hexanediamide …
Latrunculin A
Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic spindle formation and thus cell replication.
Experimental
Isothipendyl
Isothipendyl is an antihistamine and anticholinergic used as an antipruritic.
Experimental
Matched Iupac: … dimethyl(1-{9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(14),3(8),4,6,10,12-hexaen-2-yl}propan- …
Matched Salts cas: … 1225-60-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 1225-60-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
4-butyl-5-propyl-1,3-selenazol-2-amine
Experimental
Matched Synonyms: … 2-amino-4-butyl-5-propylselenazole …
Matched Name: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
Matched Iupac: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
Matched Name: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
Matched Iupac: … 4-butyl-5-propyl-1,3-selenazol-2-amine …
2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE
Experimental
Isatoribine
Isatoribine is a selective agonist of TLR7.
Investigational
Matched Iupac: … 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2H,3H,4H,7H-[1,3]thiazolo[4,5-d] …
Matched Salts cas: … 198832-38-1 …
Matched Salts cas: … 198832-38-1 …
EVT 201
EVT 201 is a novel partial positive allosteric modulator of the GABAA receptor complex which is being developed as a treatment for insomnia. It is being developed by Evotec Inc.
Investigational
Matched Iupac: … }]tetradeca-1(10),3,5,11,13-pentaen-9-one ... 11-chloro-5-{5-[(dimethylamino)methyl]-1,2,4-oxadiazol-3-yl}-8-methyl-2,4,8-triazatricyclo[8.4.0.0^{2,6 …
2'-Deoxy-2'-[(3,5-dimethoxybenzoyl)amino]-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]adenosine
Experimental
Matched Synonyms: … N-1,2,3,4-Tetrahydronaphth-1-yl-2'-[3,5-dimethoxybenzamido]-2'-deoxy-adenosine …
Matched Name: … 2'-Deoxy-2'-[(3,5-dimethoxybenzoyl)amino]-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]adenosine …
Matched Iupac: … N-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-2-(6-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-9H-purin …
Matched Name: … 2'-Deoxy-2'-[(3,5-dimethoxybenzoyl)amino]-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]adenosine …
Matched Iupac: … N-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-2-(6-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-9H-purin …
1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE
Experimental
Matched Name: … 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE …
Matched Iupac: … 1-[(2-hydroxyethoxy)methyl]-5-(phenylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 1-[(2-hydroxyethoxy)methyl]-5-(phenylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER …
(2s,5s)-5-Carboxymethylproline
Experimental
Matched Name: … (2s,5s)-5-Carboxymethylproline …
Matched Iupac: … (2S,5S)-5-(carboxymethyl)pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S,5S)-5-(carboxymethyl)pyrrolidine-2-carboxylic acid …
Displaying drugs 4251 - 4275 of 8652 in total