Displaying drugs 4326 - 4350 of 10526 in total
mRNA-3745
mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).
Investigational
Matched Description: … nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6- …
N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide
Experimental
Matched Synonyms: … N-[(benzyloxy)carbonyl]leucyl-N(1)-[3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]leucinamide …
Matched Name: … N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide …
Matched Iupac: … benzyl N-[(1S)-1-{[(1S)-1-{[(2S)-4-fluoro-1-(4-hydroxyphenyl)-3-oxobutan-2-yl]carbamoyl}-3-methylbutyl …
Matched Name: … N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide …
Matched Iupac: … benzyl N-[(1S)-1-{[(1S)-1-{[(2S)-4-fluoro-1-(4-hydroxyphenyl)-3-oxobutan-2-yl]carbamoyl}-3-methylbutyl …
Berbamine
Investigational
PVX-410 component XBP1 US184-192(YISPWILAV)
Investigational
Matched Synonyms: … L-valine, l-tyrosyl-l-isoleucyl-l-seryl-l-prolyl-l-tryptophyl-l-isoleucyl-l-leucyl-l-alanyl- …
threo-3-methyl-L-aspartic acid
Experimental
Matched Synonyms: … L-threo-3-Methylaspartate ... (3S)-3-methyl-L-aspartic acid …
Matched Name: … threo-3-methyl-L-aspartic acid …
Matched Name: … threo-3-methyl-L-aspartic acid …
Potassium triiodide
Experimental
S-adenosyl-L-homocysteine
5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
Experimental
Matched Synonyms: … 2-S-adenosyl-L-homocysteine ... S-(5'-adenosyl)-L-homocysteine ... S-[1-(adenin-9-yl)-1,5-dideoxy-β-D-ribofuranos-5-yl]-L-homocysteine …
Matched Name: … S-adenosyl-L-homocysteine …
Matched Iupac: … (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic …
Matched Description: … 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. ... Formed from S-adenosylmethionine after transmethylation reactions. …
Matched Name: … S-adenosyl-L-homocysteine …
Matched Iupac: … (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic …
Matched Description: … 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. ... Formed from S-adenosylmethionine after transmethylation reactions. …
Elzovantinib
Elzovantinib is under investigation in clinical trial NCT03993873 (Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET).
Investigational
Matched Synonyms: … benzoxatriazacyclotridecine-12-carbonitrile, 3-amino-14-ethyl-11-fluoro-4,5,6,7,13,14-hexahydro-7-methyl-4- …
N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE
Experimental
Matched Name: … N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE …
Matched Iupac: … benzyl N-[(1S)-1-{[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamoyl}-3-methylbutyl]carbamate …
Matched Iupac: … benzyl N-[(1S)-1-{[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamoyl}-3-methylbutyl]carbamate …
INT41
INT41 (also known as rAAV6-INT41) is a recombinant adeno-associated virus vector containing DNA encoding INT41 intrabody.
Investigational
BC9KBY85WY
Investigational
Matched Synonyms: … 1-piperazinecarboxamide, 4-((2e)-1-oxo-3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-yl)- ... 4-((2E)-1-Oxo-3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-yl)-1-piperazinecarboxamide …
Matched Iupac: … 4-[(2E)-3-(2,6,6-trimethylcyclohex-1-en-1-yl)prop-2-enoyl]piperazine-1-carboxamide …
Matched Iupac: … 4-[(2E)-3-(2,6,6-trimethylcyclohex-1-en-1-yl)prop-2-enoyl]piperazine-1-carboxamide …
L-deprenyl-D2 C-11
L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).
Investigational
Matched Synonyms: … (11C)L-deprenyl-D2 ... 11c-L-Selegiline-D2 …
Matched Name: … L-deprenyl-D2 C-11 …
Matched Description: … L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients …
Matched Name: … L-deprenyl-D2 C-11 …
Matched Description: … L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients …
ASP-4058
ASP4058 has been used in trials studying Food Effect of ASP4058 and Pharmacokinetics of ASP4058.
Investigational
Matched Iupac: … 5-{5-[3-(trifluoromethyl)-4-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]-1,2,4-oxadiazol-3-yl}-1H-1,3 …
Matched Salts cas: … 952510-14-4 …
Matched Salts cas: … 952510-14-4 …
CA-074 methyl ester
CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Experimental
Matched Synonyms: … (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine ... Methyl N-({(2s,3s)-3-[(propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-isoleucyl-L-prolinate ... L-Proline, N-[[(2S,3S)-3-[(propylamino)carbonyl]oxiranyl]carbonyl]-L-isoleucyl-, methyl ester …
N-Acetylmethionine
Experimental
Matched Synonyms: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid ... Acetyl-L-methionine ... L-(N-Acetyl)methionine …
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Tegoprubart
Investigational
Clonixin
Clonixin is a non-steroidal anti-inflammatory drug.
Experimental
Matched Salts cas: … 55837-30-4 …
Bimiralisib
Bimiralisib is under investigation in clinical trial NCT02723877 (PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)).
Investigational
Matched Synonyms: … 2-Pyridinamine, 5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)- ... 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine …
Matched Iupac: … 5-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)pyridin-2-amine …
Matched Iupac: … 5-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)pyridin-2-amine …
SC45647
Experimental
Matched Iupac: … 2-{[(R)-{[4-(aminomethyl)phenyl]amino}({[(1R)-1-phenylethyl]amino})methyl]amino}ethane-1,1-diol …
Quabodepistat
Investigational
Matched Synonyms: … 2(1H)-QUINOLINONE, 5-(((3R,4R)-1-(4-CHLORO-2,6-DIFLUOROPHENYL)-3,4-DIHYDROXY-4-PIPERIDINYL)METHOXY)-8 ... 5-(((3r,4r)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl)methoxy)-8-fluoro-3,4-dihydroquinolin ... 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-3,4-dihydroquinolin …
Matched Iupac: … 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-1,2,3,4-tetrahydroquinolin …
Matched Iupac: … 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-1,2,3,4-tetrahydroquinolin …
Hydroxyproline
Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved...
Experimental
Matched Synonyms: … trans-4-Hydroxy-L-proline ... trans-L-Hydroxyproline …
Matched Iupac: … (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid …
AAG-1
Investigational
Matched Synonyms: … Furo(2,3-d)pyrimidin-4-amine, n-(4-methoxyphenyl)-n,2,6-trimethyl- ... N-(4-methoxyphenyl)-n,2,6-trimethylfuro(2,3-d) pyrimidin-4-amine …
Matched Iupac: … N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine …
Matched Iupac: … N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine …
TPMPA
TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABAC receptors (also known as GABA-ρ or GABAA-ρ receptors). GABAC receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut.[A245308,A245313] TPMPA is used as a pharmacological...
Experimental
Matched Synonyms: … (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid ... P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid ... Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)- …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid …
Matched Description: … TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid …
Matched Description: … TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA …
Lerociclib
Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination With Fulvestrant in Hormone Receptor-positive, Her2-negative Locally Advanced or Metastatic Breast Cancer).
Investigational
Matched Iupac: … '-tricyclo[7.4.0.0^{2,7}]tridecane]-1'(13'),7',9',11'-tetraen-6'-one ... 12'-({5-[4-(propan-2-yl)piperazin-1-yl]pyridin-2-yl}amino)-2',5',11',13'-tetraazaspiro[cyclohexane-1,3 …
Matched Description: … Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination …
Matched Description: … Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination …
Displaying drugs 4326 - 4350 of 10526 in total