Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 426 - 450 of 12603 in total

Eflornithine

Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … 2-(difluoromethyl)ornithine ... (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Description: … [A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or interacts with ras, both ... study of children with high-risk neuroblastoma, where a 52% reduction in the risk of relapse and a 68% ... Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment …

Sutimlimab

Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures. ... (IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C ... Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies …

Iron sucrose

Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Iupac: … pentairon(3+) ion disodium (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan ... -2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol trihydrate hydroxide octaoxidandiide …
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with …
Matched Mixtures name: … Marnatal F …
Matched Products: … FE-BACK INJECTION 2% "N.K." ... HIERRO SACARATO EQUIVALENTE A HIERRO ELEMENTAL 100 MG/ 5ML. …

Quercus dumosa pollen

Quercus dumosa pollen is the pollen of the Quercus dumosa plant. Quercus dumosa pollen is mainly used in allergenic testing.
Approved

Sulfaphenazole

Sulfaphenazole is a sulfonamide antibacterial.
Approved
Matched Synonyms: … 3-(p-aminobenzenesulfonamido)-2-phenylpyrazole …
Matched Description: … Sulfaphenazole is a sulfonamide antibacterial. …

Beroctocog alfa

Approved
Investigational

Sucrose

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Synonyms: … 1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl …
Matched Description: … food and a sweetener. ... A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. ... obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Carmustine

A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Synonyms: … N,N'-Bis(2-chloroethyl)-N-nitrosourea …
Matched Iupac: … 1,3-bis(2-chloroethyl)-1-nitrosourea …
Matched Description: … A cell-cycle phase nonspecific alkylating antineoplastic agent. ... Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a …
Matched Products: … STINARED® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... CARMUSTINA 100 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK …

Nortriptyline

Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine ... 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts cas: … 894-71-3 …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Hydrocortisone acetate

Approved
Vet approved
Matched Iupac: … ,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Alcortin A ... ZISUAL-C ... Alcortin A …
Matched Products: … Poli-A ... Topiderm HC 2% ... Ekzemsalbe "F" - Agepha …

Juglans californica pollen

Juglans californica pollen is the pollen of the Juglans californica plant. Juglans californica pollen is mainly used in allergenic testing.
Approved

Levomilnacipran

Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Synonyms: … CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)- …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. ... Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is ... [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for …

Sparsentan

Sparsentan is a dual antagonist of the endothelin type A receptor (ETAR) and the angiotensin II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETAR and 0.8 nM for AT1R).[A257330,L45300] Sparsentan is first in its class and orally active, and was created by...
Approved
Investigational
Matched Iupac: … 4'-({2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl}methyl)-N-(4,5-dimethyl-1,2-oxazol-3-yl)-2'-(ethoxymethyl ... )-[1,1'-biphenyl]-2-sulfonamide …
Matched Description: … Sparsentan is a dual antagonist of the endothelin type A receptor (ETAR) and the angiotensin ... II (Ang II) type 1 receptor (AT1R) with a similar affinity for both (9.3 nM for ETA< ... In February 2023, the use of sparsentan to reduce proteinuria in adults with primary immunoglobulin A …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA) …

Etilefrine

Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Approved
Withdrawn
Matched Iupac: … 3-[2-(ethylamino)-1-hydroxyethyl]phenol …
Matched Description: … It has been used as a vasoconstrictor agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Acetyldigitoxin

Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Matched Synonyms: … Desglucolanatoside A ... Digitoxin 3'''-acetate …
Matched Iupac: … -2-methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan-4-yl acetate ... 11a-dimethyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4-hydroxy ... (2R,3R,4S,6S)-6-{[(2R,3S,4S,6S)-6-{[(2R,3S,4S,6R)-6-{[(1R,3aS,3bR,5aR,7S,9aS,9bS,11aR)-3a-hydroxy-9a, …
Matched Description: … Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tetracaine

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Synonyms: … 2-(dimethylamino)ethyl 4-(butylamino)benzoate ... 2-(Dimethylamino)ethyl p-(butylamino)benzoate ... p-Butylaminobenzoyl-2-dimethylaminoethanol …
Matched Iupac: … 2-(dimethylamino)ethyl 4-(butylamino)benzoate …
Matched Description: … Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream …
Matched Products: … TETRACAINE HYDROCHLORIDE 0.5% OPHTHALMIC SOLUTION 2 ML ... Blt 3 ... FranklyNumb 3 …

Valproic acid

Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Synonyms: … 2-Propylvaleric Acid ... 2-propyl-pentanoic acid ... 2-Propylpentanoic Acid …
Matched Iupac: … 2-propylpentanoic acid …
Matched Description: … nearly a century. ... is the subject of many clinical trials in a variety of cancer types. ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for …
Matched Categories: … UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A3 Substrates with a Narrow Therapeutic Index ... UGT1A6 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... UGT2B7 Substrates with a Narrow Therapeutic Index …
Matched Products: … EPILIM CHRONO 500MG (OBLONG FILM C* ) ... ACIDO VALPROICO E SODIO VALPROATO EG ... ACIDO VALPROICO E SODIO VALPROATO RATIOPHARM …

Gamolenic acid

Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Synonyms: … 18:3 (n-6) …
Matched Description: … It is converted to [DB00154], a biosynthetic precursor of monoenoic prostaglandins such as PGE1. …
Matched Mixtures name: … PRIM E CAPSULE ... Evening Primrose Oil + Vit E Cap ... Evening Primrose Oil Cap 500mg W Vit E …

Oxybutynin

Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Synonyms: … 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat ... 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate ... 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester …
Matched Iupac: … 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate …
Matched Description: … Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients ... symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a …
Matched Salts cas: … 1508-65-2 …

Chlorothiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Guanadrel

Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Approved
Matched Iupac: … N''-({1,4-dioxaspiro[4.5]decan-2-yl}methyl)guanidine …
Matched Salts cas: … 22195-34-2 …

Hyaluronic acid

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Iupac: … (2S,3S,4R,5R,6R)-3-{[(2S,3R,5S,6R)-4-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3-acetamido ... -5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-{[(2R,3R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl ... )oxan-4-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic acid …
Matched Description: … A popular use of hyaluronic acid in recent years is cosmetic injection due to its ability to minimize …
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... Le-Blen Vitamin C Serum ... Hyaluronic Acid 60mg and Lidocaine 2% PF …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … E- Repair ... SYNOLIS V-A ... C-eye Day …

Goldenseal

Approved
Experimental

Bean

Bean allergenic extract is used in allergenic testing.
Approved

Asparaginase Erwinia chrysanthemi

Asparaginase Erwinia chrysanthemi is an asparaginase-specific enzyme derived from Erwinia chrysanthemi used as an anticancer agent. It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death. L-asparaginase was first identified in...
Approved
Investigational
Matched Description: … and there are different formulations of L-asparaginase, including [Asparaginase Escherichia coli] and a ... component of a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic lymphoma ... In June 2021, the recombinant form of asparaginase _Erwinia chrysanthemi_ was approved by the FDA as a …
Displaying drugs 426 - 450 of 12603 in total