Displaying drugs 426 - 450 of 15574 in total
Oxeladin
Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity.
Approved
Withdrawn
Matched Synonyms: … 2-(2-Diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate …
Matched Iupac: … 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. …
Matched Iupac: … 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … (−)-2-pyrrolidone-5-carboxylic acid ... 5-Pyrrolidone-2-carboxylic acid ... 5-oxo-2-pyrrolidinecarboxylic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... Although pidolic acid is included in some over-the-counter, non-prescription dietary supplements for …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Products: … MAG 2 ... Mag 2 Pwr 1.5gm/pck …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... Although pidolic acid is included in some over-the-counter, non-prescription dietary supplements for …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Products: … MAG 2 ... Mag 2 Pwr 1.5gm/pck …
Burosumab
Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets .
The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. ... XLH is a serious disease which affects about 3,000 children and 12,000 adults in the United States. ... throughout a patient’s life [L2346]. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … CRYSVITA 10 MG SOLUTION FOR INJECTION ... CRYSVITA 20 MG SOLUTION FOR INJECTION ... CRYSVITA 30 MG SOLUTION FOR INJECTION …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … CRYSVITA 10 MG SOLUTION FOR INJECTION ... CRYSVITA 20 MG SOLUTION FOR INJECTION ... CRYSVITA 30 MG SOLUTION FOR INJECTION …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … [2-(2-pyridyl)ethyl]methylamine ... 2-[2-(methylamino)ethyl]pyridine ... N-methyl-2-(2-pyridinyl)ethanamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated ... It is currently marketed in Canada by various companies, including Teva Pharmaceuticals. ... [A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated ... It is currently marketed in Canada by various companies, including Teva Pharmaceuticals. ... [A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately …
Zopiclone
Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.
Approved
Matched Synonyms: … 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate …
Matched Iupac: … 6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Description: … Zopiclone is a novel hypnotic agent used in the treatment of insomnia. ... In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like …
Matched Iupac: … 6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Description: … Zopiclone is a novel hypnotic agent used in the treatment of insomnia. ... In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like …
Mexiletine
Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Synonyms: … 1-(2',6'-dimethylphenoxy)-2-aminopropane ... 1-methyl-2-(2,6-xylyloxy)ethanamine ... (±)-1-(2,6-dimethylphenoxy)propan-2-amine …
Matched Iupac: … 1-(2,6-dimethylphenoxy)propan-2-amine …
Matched Iupac: … 1-(2,6-dimethylphenoxy)propan-2-amine …
Denileukin diftitox
A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Synonyms: … Interleukin-2/diptheria toxin fusion protein …
Matched Description: … It is produced in an E. coli expression system. ... fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133 ... A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin …
Matched Description: … It is produced in an E. coli expression system. ... fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133 ... A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin …
Thiopental
A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Synonyms: … 2-Thio-5-ethyl-5-sec-pentylbarbituric acid ... 5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dione …
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione …
Matched Description: … A barbiturate that is administered intravenously for the induction of general anesthesia or for the production ... It has been used in neurosurgical patients to reduce increased intracranial pressure. ... It is also used for hypnosis and for the control of convulsive states. …
Matched Categories: … Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Products: … ANES 1.0 (THIOPENTAL SODIUM FOR INJECTION BP) …
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione …
Matched Description: … A barbiturate that is administered intravenously for the induction of general anesthesia or for the production ... It has been used in neurosurgical patients to reduce increased intracranial pressure. ... It is also used for hypnosis and for the control of convulsive states. …
Matched Categories: … Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Products: … ANES 1.0 (THIOPENTAL SODIUM FOR INJECTION BP) …
Luspatercept
Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients...
Approved
Investigational
Matched Description: … [A187829,L42455] It was first approved for use in the United States in November 2019 under the brand ... Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin ... name Reblozyl® for the treatment of anemia in patients with beta thalassemia who require regular blood …
Matched Products: … Reblozyl 25 mg powder for solution for injection ... Reblozyl 75 mg powder for solution for injection …
Matched Products: … Reblozyl 25 mg powder for solution for injection ... Reblozyl 75 mg powder for solution for injection …
Casein
Casein allergenic extract is used in allergenic testing.
Approved
Matched Description: … Casein allergenic extract is used in allergenic testing. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Becaplermin
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Synonyms: … PDGF-2 …
Matched Description: … Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical ... Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet …
Matched Categories: … Proto-Oncogene Proteins c-sis ... Preparations for Treatment of Wounds and Ulcers …
Matched Description: … Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical ... Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet …
Matched Categories: … Proto-Oncogene Proteins c-sis ... Preparations for Treatment of Wounds and Ulcers …
Influenza A virus A/West Virginia/30/2022 (H1N1) Recombinant Hemagglutinin Antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/West Virginia/30/2022 (H1N1) Recombinant Hemagglutinin Antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection …
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Description: … C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase ... Deficiency of C1-inhibitor allows for increased plasma kallikrein activation and subsequent production ... Marketed as the product Ruconest (FDA), this drug is indicated for the treatment of acute attacks of …
Matched Categories: … Drugs Used in Hereditary Angioedema …
Matched Categories: … Drugs Used in Hereditary Angioedema …
Avelumab
Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) ... It is used in the treatment of Merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell …
Matched Products: … BAVENCIO CONCENTRATE FOR SOLUTION FOR INFUSION 200MG/10ML ... BAVENCIO 200 mg/10mL concentrate for solution for infusion …
Matched Products: … BAVENCIO CONCENTRATE FOR SOLUTION FOR INFUSION 200MG/10ML ... BAVENCIO 200 mg/10mL concentrate for solution for infusion …
Nalbuphine
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States. ... A narcotic used as a pain medication. …
Matched Salts cas: … 23277-43-2 …
Matched Salts cas: … 23277-43-2 …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Synonyms: … Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2- ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Mixtures name: … BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET …
Matched Categories: … Drugs for Constipation …
Matched Products: … Lax-A Go ... C-Lax Laxative ... C Lax Laxative …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2- ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Mixtures name: … BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET …
Matched Categories: … Drugs for Constipation …
Matched Products: … Lax-A Go ... C-Lax Laxative ... C Lax Laxative …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Description: … [A232955] Avalglucosidase alfa is a recombinant form of GAA that restores deficient enzyme levels. ... Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe ... GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. …
Matched Products: … NEXVIAZYME 100mg Powder for Concentrate for Solution for Infusion …
Matched Products: … NEXVIAZYME 100mg Powder for Concentrate for Solution for Infusion …
Betaine
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-(Trimethylammonio)Acetate ... 2-trimethylammonioacetate ... 2-N,N,N-trimethylammonio acetate …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating ... Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. ... [L43115] Betaine reduces plasma homocysteine levels in patients with homocystinuria. …
Matched Mixtures name: … Ultr F/b E.S. Mega Lipotropic Fmla W B6bet …
Matched Products: … Betaine Anhydrous For Oral Solution ... Betaine Anhydrous for Oral Solution …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Description: … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating ... Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. ... [L43115] Betaine reduces plasma homocysteine levels in patients with homocystinuria. …
Matched Mixtures name: … Ultr F/b E.S. Mega Lipotropic Fmla W B6bet …
Matched Products: … Betaine Anhydrous For Oral Solution ... Betaine Anhydrous for Oral Solution …
Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen
Approved
Matched Synonyms: … Nimenrix component neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Name: … Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Products: … NeisVac-C Injektionssuspension in einer Fertigspritze …
Matched Name: … Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Products: … NeisVac-C Injektionssuspension in einer Fertigspritze …
Butorphanol
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Approved
Illicit
Vet approved
Matched Iupac: … (1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4,10 …
Matched Description: … It is used in the management of severe pain. ... A synthetic morphinan analgesic with narcotic antagonist action. …
Matched Description: … It is used in the management of severe pain. ... A synthetic morphinan analgesic with narcotic antagonist action. …
Durvalumab
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that attack tumour...
Approved
Investigational
Matched Description: … [L12621] In September 2018, durvalumab was approved by the EMA for the treatment of adult patients with ... It was granted accelerated approval by the FDA in May 2017 [A192807] for the treatment of selected patients ... [A192789,L12627] On March 27, 2020, durvalumab was approved by the FDA for use in combination with [etoposide …
Matched Products: … IMFINZI CONCENTRATE FOR SOLUTION FOR INFUSION 50 MG/ML ... IMFINZI CONCENTRATE FOR SOLUTION FOR INTRAVENOUS INFUSION 50 MG/ML …
Matched Products: … IMFINZI CONCENTRATE FOR SOLUTION FOR INFUSION 50 MG/ML ... IMFINZI CONCENTRATE FOR SOLUTION FOR INTRAVENOUS INFUSION 50 MG/ML …
Iron sucrose
Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Iupac: … pentairon(3+) ion disodium (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan ... -2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol trihydrate hydroxide octaoxidandiide …
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with ... Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease …
Matched Mixtures name: … Marnatal F …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … FE-BACK INJECTION 2% "N.K." ... Venofer Solution for Injection 20mg/ml ... HIERRO SACARATO EQUIVALENTE A HIERRO ELEMENTAL 100 MG/ 5ML. …
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with ... Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease …
Matched Mixtures name: … Marnatal F …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … FE-BACK INJECTION 2% "N.K." ... Venofer Solution for Injection 20mg/ml ... HIERRO SACARATO EQUIVALENTE A HIERRO ELEMENTAL 100 MG/ 5ML. …
Deferoxamine
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Approved
Investigational
Matched Iupac: … N-(5-aminopentyl)-N-hydroxy-N'-[5-(N-hydroxy-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propanamido)pentyl …
Matched Description: … It forms iron complexes and is used as a chelating agent, particularly in the mesylate form. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Desferal 500mg Powder for Solution for Injection ... Deferoxamine Mesylate for Injection ... DBL DESFERRIOXAMINE MESYLATE FOR INJECTION BP 500 mg/vial …
Matched Description: … It forms iron complexes and is used as a chelating agent, particularly in the mesylate form. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Desferal 500mg Powder for Solution for Injection ... Deferoxamine Mesylate for Injection ... DBL DESFERRIOXAMINE MESYLATE FOR INJECTION BP 500 mg/vial …
Guanadrel
Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Approved
Matched Iupac: … N''-({1,4-dioxaspiro[4.5]decan-2-yl}methyl)guanidine …
Matched Salts cas: … 22195-34-2 …
Matched Salts cas: … 22195-34-2 …
Displaying drugs 426 - 450 of 15574 in total