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Displaying drugs 426 - 450 of 2366 in total
Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Iupac: … (16R)-19-amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetraazatetracyclo[16.3.1.0^{2,6}.0^{ …
Matched Products: … LORVIQUA (TABLETS 100 MG) ... Lorviqua 100 mg Film-Coated Tablets …
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Mixtures name: … ETNA COMBO 100 MG/8 MG TABLET, 14 ADET ... NİMES COMBO 100 MG / 8 MG TABLET , 14 ADET …
Matched Products: … AINEDIX®100 MG ... NIMESULIDA 100 MG ... NIMESULIDE 100 MG …
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Mixtures name: … EMEDUR 200 MG SUPOZITUAR, 100 ADET ... EMEDUR 100 MG/20 MG SUPOZİTUAR, 5 ADET …
Matched Products: … VOMITIN 100 MG 6 AMPUL ... AMETIK 100 MG 15 ML DAMLA ... VOMET 100 MG SUPPOZITUVAR , 5 ADET …
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0) …
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Salts cas: … 17795-21-0
Matched Products: … ISORIC 100 ... REUCID 100 ... CORIC 100
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Mixtures name: … ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET ... ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET …
Matched Products: … LACOLEP 100 ... LAKOMID® 100 ... VIMPAT® 100 MG TABLETAS …
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Products: … DOXYMYCIN-100 CAPSULES 100 mg ... Doxy 100 ... โปลีไซคลีน 100
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Products: … CANDIFORCE-100 Itraconazole Capsules BP 100 mg ... Inox Capsule 100 mg ... MICOTRAZOL® 100 MG …
Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal glucoamylase, sucrase, maltase, and isomaltase - which are responsible for the metabolism of complex starches and...
Approved
Investigational
Matched Products: … GLUCOBAY 100 TABLET 100 mg ... DITRIUM 100 ... GLUCOBAY 100
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Products: … ทาโรซิน 100 ... โอเฟล็กซ์-100 ... โอฟล็อกซิล 100
Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Approved
Matched Products: … ELMIRON 100 MG KAPSÜL, 100 ADET ... Elmidam 100 mg Sert Kapsül, 100 ADET ... ELMİDAM 100 MG SERT KAPSÜL, 100 ADET …
Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
Approved
Investigational
Matched Products: … ANIDACCORD 100 POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG ... FUNİDUL 100 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... ERAXIS 100 MG INF. COZ. ICIN TOZ ICEREN FLAKON, 1 ADET VE COZUCU …
In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic...
Approved
Investigational
Matched Products: … NEURONOX® 100 UI ... XEOMIN®100 U LD50 ... XEOMIN (100 LD50 UNIT) …
Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated...
Approved
Investigational
Matched Products: … VIGIA® 100 MG ... CARIM 100 MG ... Modasomil 100 mg Tabletten …
A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Approved
Investigational
Matched Mixtures name: … KATACOLD 120 MG + 3.75 MG+ l MG /5 ML PEDIYATRIK ŞURUP, 100 ML …
Matched Products: … KAF 7,5 MG / 5 ML SURUP, 100 ML ... KREVAL7.5 MG/5 ML ŞURUP, 100 ML ... CODACTIV M 15 MG/5 ML ŞURUP, 100 ML …
A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Products: … มีเบนคาร์ 100 มก. ... น็อกซ์เวิม - 100 ... Pantelmin 100 mg - Tabletten …
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Products: … SYMMETREL 100 CAPSULE 100 mg ... AMANTADIN AL 100 ... AMANTADINA 100 MG …
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Salts cas: … 79559-97-0
Matched Products: … Inosert-100 (Sertraline Tablets 100 mg) ... Sertraline-100 ... AURASERT 100
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … [L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), …
Matched Products: … PİFELTRO 100 MG FİLM KAPLI TABLET, 30 ADET …
Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam . It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 .
Approved
Investigational
Matched Products: … BRIVIACT 100 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET ... BRIVIACT 100 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET ... BRIVIACT 100 MG FILM KAPLI TABLET ,168 FILM KAPLI TABLET …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Salts cas: … 171599-83-0
Matched Products: … VIAJOY 100 ... AMIGRA 100 ... SINAFIL-100
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Salts cas: … 1240039-02-4 …
Matched Mixtures name: … สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม) ... สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม) …
Matched Products: … จิมเวีย 100 ... 100 mg tablet ... จานูเวีย (100 มก.) …
Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications such as...
Approved
Vet approved
Matched Products: … EPANUTIN 100 MG KAPSUL, 100 ADET ... EPDANTOIN 100 MG TABLET, 100 TABLET ... KUTOIN 100
Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Iupac: … pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^ …
Matched Mixtures name: … RIF 250 MG AMPUL, 100 ADET ... RIFOCIN 125 MG+5 MG/1,5 ML IM ENJEKSİYON İÇİN SOLÜSYON İÇEREN AMPUL, 100 ADET ... RIFOCIN 250 MG+10 MG/3 ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 100 ADET …
Matched Products: … RIFAL IM 125 MG AMPUL, 100 ADET ... RIFAL IM 250 MG AMPUL, 100 ADET …
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Description: … /β0). ... /sup>/β0 genotype) compared to those with no detectable β-globin production (β0 ... autotemcel is more effective in patients with β-thalassemia with residual β-globin synthesis (non-β0< …
Displaying drugs 426 - 450 of 2366 in total