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Displaying drugs 426 - 450 of 9443 in total
Indacaterol
Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Iupac: … 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1,2-dihydroquinolin ... -2-one …
Matched Description: … Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis …
Matched Salts cas: … 1000160-96-2 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Selective Beta 2-adrenergic Agonists …
Matched Description: … Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis …
Matched Salts cas: … 1000160-96-2 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Selective Beta 2-adrenergic Agonists …
Palovarotene
Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million individuals, is an exceptionally rare genetic disorder. FOP is caused by a gain-of-function mutation in the ACVR1/ALK2 gene which results in progressive heterotopic ossification, a process wherein connective tissues (e.g. skeletal muscle, ligaments, tendons) are replaced...
Approved
Investigational
Matched Iupac: … 4-[(1E)-2-{5,5,8,8-tetramethyl-3-[(1H-pyrazol-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl}ethenyl] …
Matched Description: … Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million …
Matched Description: … Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million …
Polatuzumab vedotin
Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … [2-(2-pyridyl)ethyl]methylamine ... 2-[2-(methylamino)ethyl]pyridine ... N-methyl-2-(2-pyridinyl)ethanamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately 5 …
Matched Salts cas: … 133206-34-5 …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately 5 …
Matched Salts cas: … 133206-34-5 …
Vemurafenib
Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Iupac: … N-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Articaine
Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Matched Iupac: … methyl 4-methyl-3-[2-(propylamino)propanamido]thiophene-2-carboxylate …
Matched Mixtures name: … MAXİCAİNE 80 MG/2 ML+0,01 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL ... Orabloc 40 mg/ml + 5 Mikrogramm/ml Injektionslösung ... Ubistesin 40 mg/ml + 5 Mikrogramm/ml - Injektionslösung …
Matched Mixtures name: … MAXİCAİNE 80 MG/2 ML+0,01 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL ... Orabloc 40 mg/ml + 5 Mikrogramm/ml Injektionslösung ... Ubistesin 40 mg/ml + 5 Mikrogramm/ml - Injektionslösung …
N-acetyltyrosine
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Synonyms: … (2s)-2-acetylamino-3-(4-hydroxyphenyl)propanoic acid ... (+)-(2s)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Mixtures name: … Aminosyn II 5% Inj ... AMINOPLASMAL-5% E INFUSION …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Mixtures name: … Aminosyn II 5% Inj ... AMINOPLASMAL-5% E INFUSION …
Benzyl alcohol
Approved
Matched Mixtures name: … ZOLBENE CREMA TOPICA (CALAMINA 5% + OXIDO DE ZINC 5% + ALCOHOL BENCILICO 1%) …
Miltefosine
Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease. It can be administered topically or orally and...
Approved
Investigational
Matched Synonyms: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Iupac: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Iupac: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Avelumab
Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Turoctocog alfa pegol
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019.
Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Posaconazole
Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Iupac: … )piperazin-1-yl]phenyl}-1-[(2S,3S)-2-hydroxypentan-3-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one ... 4-{4-[4-(4-{[(3R,5R)-5-(2,4-difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-yl]methoxy}phenyl …
Alginic acid
Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Mixtures name: … MAGCAR 680 MG+80 MG/5 ML SÜSPANSİYON, 100 ML ... GASTOPAL DUO 600 MG+70 MG+150 MG/5 ML SÜSPANSİYON, 100 ML ... RENNIE DUO 600 MG+ 70 MG+150 MG/5 ML SUSPANSIYON, 100 ML …
Lixisenatide
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Mixtures name: … SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM ... SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM …
Matched Products: … LYXUMIA 20 MCG ENJEKSIYON IÇIN ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM ,2 KALEM …
Matched Products: … LYXUMIA 20 MCG ENJEKSIYON IÇIN ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM ,2 KALEM …
Methylphenidate
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Synonyms: … methyl phenyl(piperidin-2-yl)acetate ... methyl α-phenyl-α-(2-piperidyl)acetate ... methyl α-phenyl-α-2-piperidinylacetate …
Matched Iupac: … methyl 2-phenyl-2-(piperidin-2-yl)acetate …
Matched Products: … Medikinet 5 mg Tabletten ... Medikinet retard 5 mg Hartkapseln mit veränderter Wirkstofffreisetzung …
Matched Iupac: … methyl 2-phenyl-2-(piperidin-2-yl)acetate …
Matched Products: … Medikinet 5 mg Tabletten ... Medikinet retard 5 mg Hartkapseln mit veränderter Wirkstofffreisetzung …
alpha-Arbutin
Approved
Experimental
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol …
Matched Mixtures name: … I-max Lightening 5 …
Matched Mixtures name: … I-max Lightening 5 …
Metrizoic acid
Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated. A total of...
Approved
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoic acid …
Matched Description: … Seven cases of ventricular fibrillation, and 5 of significant bradycardia/asystole, were associated with …
Matched Salts cas: … 20828-80-2 …
Matched Description: … Seven cases of ventricular fibrillation, and 5 of significant bradycardia/asystole, were associated with …
Matched Salts cas: … 20828-80-2 …
Quercus macrocarpa pollen
Quercus macrocarpa pollen is the pollen of the Quercus macrocarpa plant. Quercus macrocarpa pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 5-oak Mix, Blackjack/bur/post/red/white Pollen …
Trandolapril
Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure...
Approved
Matched Iupac: … 2-carboxylic acid ... (2S,3aR,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydro-1H-indole- …
Matched Salts cas: … 87725-72-2 …
Matched Mixtures name: … TARKA 180/2 FILM TABLET, 28 ADET ... VERACOMB MR 180/2 MG KAPSÜL, 28 ADET ... VERAPIN 180 MG/2 MG FILM TABLET, 28 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … GOPTEN 2 MG KAPSUL, 28 ADET …
Matched Salts cas: … 87725-72-2 …
Matched Mixtures name: … TARKA 180/2 FILM TABLET, 28 ADET ... VERACOMB MR 180/2 MG KAPSÜL, 28 ADET ... VERAPIN 180 MG/2 MG FILM TABLET, 28 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … GOPTEN 2 MG KAPSUL, 28 ADET …
Triflupromazine
A phenothiazine used as an antipsychotic agent and as an antiemetic.
Approved
Vet approved
Matched Synonyms: … 2-(Trifluoromethyl)promazine ... 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine ... 2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine …
Matched Iupac: … dimethyl({3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl})amine …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Matched Iupac: … dimethyl({3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl})amine …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Estrone sulfate
Estrone sulfate (as estropipate) is a form of estrogen. It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelopment of female sexual characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer...
Approved
Matched Salts cas: … 438-67-5 …
Matched Categories: … MATE 2 Substrates …
Matched Categories: … MATE 2 Substrates …
Clocortolone
Clocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Approved
Matched Iupac: … (1S,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-9b-chloro-5-fluoro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl …
Salmeterol
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Iupac: … 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol …
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Betaine
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-(Trimethylammonio)Acetate ... 2-trimethylammonioacetate ... 2-N,N,N-trimethylammonio acetate …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Salts cas: … 590-46-5 …
Matched Iupac: … 2-(trimethylazaniumyl)acetate …
Matched Salts cas: … 590-46-5 …
Displaying drugs 426 - 450 of 9443 in total