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Displaying drugs 426 - 450 of 2753 in total

Mozafancogene autotemcel

RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …

CP-12

Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-ethyl-5-(sec-pentyl)barbituric acid ... 5-ethyl-5-(1-methylbutyl)barbituric acid …
Matched Description: … agent and is usually given orally. ... A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) …
Matched Salts name: … Pentobarbital Sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Nembutal Sodium ... Pentobarbital Sodium ... Nembutal Sodium Cap 100mg …

Butabarbital

Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Synonyms: … 5-sec-butyl-5-ethylbarbituric acid ... 5-ethyl-5-(1-methylpropyl)barbituric acid …
Matched Description: … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Butabarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Butisol Sodium ... Butisol Sodium Tab 30mg ... Butisol Sodium Tab 15mg …

Amobarbital

A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Synonyms: … 5-ethyl-5-isoamylbarbituric acid ... 5-ethyl-5-isopentylbarbituric acid ... 5-ethyl-5-(3-methylbutyl)barbituric acid …
Matched Description: … A barbiturate with hypnotic and sedative properties (but not antianxiety). ... Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Salts name: … Amobarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Amytal Sodium ... Amytal Sodium Cap 60mg ... Amytal Sodium 500mg …

Ceftazidime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Description: … a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone …
Matched Salts name: … Ceftazidime sodium …
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Synonyms: … Acide risédroniqe ... Acido risedronico ... Risedronic acid …
Matched Name: … Risedronic acid …
Matched Iupac: … [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid …
Matched Description: … Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of ... osteoperosis and Paget's disease[FDA Label][A959,A203111]. …
Matched Mixtures name: … Risedronate Sodium ... Risedronate Sodium ... Risedronate Sodium …
Matched Salts name: … Risedronate sodium ... Risedronate sodium monohydrate ... Risedronate sodium hemi-pentahydrate …
Matched Categories: … risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential ... Calcium-Regulating Hormones and Agents ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Risedronate Sodium ... Risedronate Sodium Amorphous Fv2910cl ... RISEDRONATO SODICO 150 MG …

Trichloroacetate

Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and...
Approved
Matched Description: … , DNA and RNA. ... In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins ... Trichloroacetate is also found in cosmetic treatments and topical formulations as a cauterant, which …
Matched Salts name: … Trichloroacetic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Trichloroacetic Acid …
Matched Products: … Trichloroacetic Acid 30% ... Trichloroacetic Acid 15% ... Trichloroacetic Acid 50% …

Factor IX Complex (Human)

Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …

Colistin

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes …
Matched Mixtures name: … COLISTINA SULFATO+HIDROCORTISONA ACETATO+NEOMICINA SULFATO ... COLISTINA SULFATO+HIDROCORTISONA ACETATO+NEOMICINA SULFATO …
Matched Salts name: … Colistin sulfate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Pore Forming Cytotoxic Proteins …
Matched Products: … COLISTIMETATO SODICO ALTAN ... COLISTIMETATO SODICO NORIDEM ... COLISTIMETATO SODICO NORIDEM LTD. …

Hydrocortisone succinate

Approved
Matched Iupac: … 3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}-4-oxobutanoic acid …
Matched Salts name: … Hydrocortisone sodium succinate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … HYDROCORTISONE SODIUM SUCCINATE ... Hydrocortisone Sodium Succinate Injection ... Hydrocortisone Sodium Succinate for Injection …

Chlorothiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Synonyms: … 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Salts name: … Chlorothiazide sodium …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... chlorothiazide and potassium …
Matched Products: … DIURIL Sodium ... Sodium Diuril ... Chlorothiazide Sodium …

Potassium sodium hydrogen citrate

Experimental
Matched Synonyms: … Potassium sodium hydrogen citrate ... Sodium potassium hydrogen citrate …
Matched Name: … Potassium sodium hydrogen citrate …

Desonide sodium phosphate

Experimental
Matched Name: … Desonide sodium phosphate …

Ivermectin

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and ... also be effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep …

Dantrolene

Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Approved
Investigational
Matched Salts name: … Dantrolene sodium …
Matched Categories: … Dantrolene and Derivatives …
Matched Products: … Dantrolene Sodium ... RYANODEX dantrolene sodium ... Dantrolene Sodium for Injection, USP …

Hydrocortisone acetate

Approved
Vet approved
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid …

Diatrizoate

A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Synonyms: … Urografin acid ... Diatrizoic acid ... Methalamic acid …
Matched Iupac: … 3,5-diacetamido-2,4,6-triiodobenzoic acid …
Matched Description: … As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography ... , and urography. …
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium …
Matched Salts name: … Diatrizoate sodium ... Diatrizoic acid dihydrate …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... diatrizoic acid ... Triiodobenzoic Acids …
Matched Products: … Hypaque Sodium ... Hypaque Sodium 50% Liq ... Hypaque Sodium Liq 50% …

Fenofibric acid

Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid …
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid …
Matched Description: … ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia ... , and mixed dyslipidemia. …
Matched Categories: … Acids, Acyclic ... Fibric Acids ... Carboxylic Acids …
Matched Products: … Fenofibric Acid ... Fenofibric acid ... Fenofibric Acid Delayed-Release …

Amyl Nitrite

Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning. Its use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal...
Approved
Matched Synonyms: … n-Amyl nitrite ... pentyl nitrite ... n-pentyl nitrite …
Matched Name: … Amyl Nitrite …
Matched Iupac: … pentyl nitrite …
Matched Description: … Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning ... Amyl Nitrite is an antihypertensive medicine. …
Matched Categories: … Nitrites ... amyl nitrite ... Organic Nitrates …
Matched Products: … Amyl Nitrite ... AMYL NITRITE INHALANT USP 0.3 ml/ampoule ... Amyl Nitrite Vitrellae Bpc Liq 0.33 Ml/cap …

Prednisolone phosphate

Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Iupac: … acid ... 11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic …
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Salts name: … Prednisolone sodium phosphate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Prednisolone Sodium Phosphate ... Prednisolone Sodium Phosphate ODT ... Prednisolone Sodium Phosphate Oral Solution …

Fosphenytoin

Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Approved
Investigational
Matched Iupac: … [(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methoxy]phosphonic acid …
Matched Description: … Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium ... channels, and therefore limit repetitive firing of action potentials. …
Matched Salts name: … Fosphenytoin sodium …
Matched Categories: … Phenytoin and Prodrugs ... Sodium Channel Blockers …
Matched Products: … Fosphenytoin Sodium ... Fosphenytoin sodium …

Secobarbital

Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Synonyms: … 5-allyl-5-(1-methylbutyl)barbituric acid …
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. …
Matched Salts name: … Secobarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Seconal Sodium ... Seconal Sodium Pulvule 240 0.1gm …

Neoarsphenamine

Investigational
Withdrawn
Matched Synonyms: … Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium ... Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …

Atropine

Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched Description: … [A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous ... It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active ... , subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Salts name: … Atropine sulfate ... Atropine sulfate anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... Mydriatics and Cycloplegics ... pralidoxime and atropine ... atropine and psycholeptics …
Matched Products: … Atropine Sulfate ... ATROPINE SULFATE ... ATROPINE SULPHATE …
Displaying drugs 426 - 450 of 2753 in total