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Displaying drugs 4626 - 4650 of 10619 in total
GS-441524
GS-441524 is an adenosine nucleotide analog antiviral, similar to remdesivir.[A203057,L13239] This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent.[A203057,A203057] GS-441524 continues to be studied in the treatment of Feline...
Experimental
Matched Description: … [A203057,L13239] This molecule was patented in 2009. ... against a number of viruses, meaning GS-441524 is less potent. ... [L13775] _In vitro_ studies of GS-441524 have determined it has a higher EC50 than remdesivir …
Pexacerfont
Pexacerfont has been investigated for the treatment of Alcoholism, Anxiety Disorder, Alcohol Dependence, and Alcohol-Related Disorders.
Investigational
Matched Description: … Pexacerfont has been investigated for the treatment of Alcoholism, Anxiety Disorder, Alcohol Dependence …
Citiolone
Experimental
Doramectin
Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.
Vet approved
Matched Iupac: … (1'R,2S,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-6-cyclohexyl-21',24'-dihydroxy-12'-{[( …
Matched Description: … Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites …
Matched Description: … Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites …
Eprinomectin
Vet approved
Matched Iupac: … N-[(2S,3R,4R,6S)-6-{[(2S,3R,4S,6R)-6-[(1'R,2S,4'S,5S,6R,8'R,10'Z,12'S,13'S,14'Z,16'Z,20'R,21'R,24'S)- …
Maltose
A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).
Experimental
Investigational
Matched Description: … It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Putrescine
Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more than one amine group. Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme.
Experimental
Matched Description: … , and S-adenosylmethionine decarboxylase proenzyme. ... Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine ... Known drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase …
Talarozole
Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
Investigational
Matched Description: … Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Methallenestril
Experimental
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Mephedrone
Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.
Investigational
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine
25CN-NBOH (N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine) is a newly developed selective 5-HT2A agonist. It has been tested with regard to the head-twitch-response (HTR) model of 5-HT2A activity and effects on locomotion . It was discovered in 2014 at the University of Copenhagen.
Experimental
Matched Description: … It was discovered in 2014 at the University of Copenhagen. ... It has been tested with regard to the head-twitch-response (HTR) model of 5-HT2A activity and effects …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Benzimate
Benzimate is the lead compound selected from a series of compounds known as benzimidazoles. The anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor & Gamble Company beginning in the 1990's. It is currently under investigation by AmpliMed and is in phase I of clinical trial.
Investigational
Matched Description: … & Gamble Company beginning in the 1990's. ... Benzimate is the lead compound selected from a series of compounds known as benzimidazoles. ... It is currently under investigation by AmpliMed and is in phase I of clinical trial. …
Vorozole
Experimental
Matched Iupac: … 6-[(S)-(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H-1,2,3-benzotriazole …
Virginiamycin M1
Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.
Experimental
Matched Description: … Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and ... one component of pristinamycin. …
Butyrylthiocholine
A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem]
Experimental
Matched Description: … It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem] ... A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate …
Arotinolol
Arotinolol is an alpha- and beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy. Artinolol is being developed by Sumitomo Pharmaceutical Co., Ltd. and it is currently under clinical trials.
Investigational
Acetone Cyanohydrin
Experimental
EVT 201
EVT 201 is a novel partial positive allosteric modulator of the GABAA receptor complex which is being developed as a treatment for insomnia. It is being developed by Evotec Inc.
Investigational
Matched Description: … EVT 201 is a novel partial positive allosteric modulator of the GABAA receptor complex which is being …
Bifemelane
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Dalcetrapib
Dalcetrapib is under investigation for the treatment of Acute Coronary Syndrome.
Investigational
Matched Description: … Dalcetrapib is under investigation for the treatment of Acute Coronary Syndrome. …
Cositecan
Cositecan is the novel camptothecin derivative which is also known as Karenitecin. It has been developed for superior oral bioavailability and increased lactone stability. It is used to treat cancer.
Investigational
Phenoxypropazine
Phenoxypropazine is a non-selective and irreversible monoamine oxidase enzyme inhibitor (MAOI), belonging to the hydrazine chemical class. It was marketed as an antidepressant in 1961 but was later withdrawn in 1966 because of its hepatotoxic potential.
Withdrawn
Matched Description: … It was marketed as an antidepressant in 1961 but was later withdrawn in 1966 because of its hepatotoxic …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 4626 - 4650 of 10619 in total