Doramectin

DB11400ExperimentalVet approvedSmall molecule

Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in...

Mechanism: Pharmacologically active on Anoctamin-1
Curator reviewed
Formula / weight: C₅₀H₇₄O₁₄ · 899.128 g/mol (avg)
Code names: L-701023 · UK-67,994

Resolves to

Compound

UNIIKGD7A54H5PCAS117704-25-3ChEMBLCHEMBL2361641

Clinical / RWD

RxNorm73455

Structure

InChIKeyQLFZZSKTJWDQOS-YDBLARSUSA-NSMILES

[H][C@@]12OC\C3=C/C=C/[C@H](C)[C@H](O[C@@]4([H])C[C@H](OC)[C@@H](O[C@@]5([H])C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)\C(C)=C\C[C@@H]4C[C@@H](C[C@]5(O4)O[C@H](C4CCCCC4)[C@@H](C)C=C5)OC(=O)[C@]([H])(C=C(C)[C@H]1O)[C@@]23O

Targets

Q5XXA6ANO1

Transporters

Q9Y6L6SLCO1B1P08183ABCB1

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2TransportersSubstrate / inhibitor direction, not just membership

Listed above

1Marketed productAcross 1 country and 1 labeller

14+ReferencesStructured and connected to the statements they support

Which drugs share a target with Doramectin, and which of those have an active Phase 3 trial?

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