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Displaying drugs 451 - 475 of 724 in total
Dociparstat sodium
Investigational
Matched Synonyms: … 2,3-o-Desulfated heparin (12000 da) …
Matched Categories: … Heparin and similars …
Matched Categories: … Heparin and similars …
Meropenem
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death.
In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Synonyms: … 4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo …
Matched Iupac: … 5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo …
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP ... Merozan 500mg powder for solution for injection or infusion …
Matched Iupac: … 5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo …
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP ... Merozan 500mg powder for solution for injection or infusion …
Heparin
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... coagulation enzymes thrombin (factor IIa) and factor Xa. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs ... Heparins or Heparinoids for Topical Use …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs ... Heparins or Heparinoids for Topical Use …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
Prilocaine
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Synonyms: … 2-(Propylamino)-o-propionotoluidide ... o-Methyl-2-propylaminopropionanilide ... o-Methyl-alpha-propylaminopropionanilide …
Matched Mixtures name: … Lidocaine and Prilocaine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Matched Mixtures name: … Lidocaine and Prilocaine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
2'-deoxyuridine 5'-alpha,beta-imido-diphosphate
Experimental
Matched Synonyms: … 2'-Deoxy-5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]uridine …
KIT-13
Investigational
Matched Synonyms: … 1-o-octadecyl-2-arachidonoyl-sn-glycerol-3-phosphoethanolamine …
Telitacicept
Investigational
Matched Synonyms: … (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Butanilicaine
Experimental
Matched Synonyms: … 2-(Butylamino)-6'-chloro-o-acetoluidide ... 2-Butylamino-6'-chloro-o-acetotoluidide …
Topiramate
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate ... 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate …
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and ... 40% of its mass accounted for by oxygen. …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and ... 40% of its mass accounted for by oxygen. …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Epigallocatechin gallate
Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Investigational
Matched Synonyms: … (-)-EPIGALLOCATECHIN-3-O-GALLATE ... EPIGALLOCATECHIN 3-O-GALLATE ... 3-O-GALLOYL-(-)-EPIGALLOCATECHIN …
Matched Description: … Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy …
Matched Categories: … Compounds used in a research, industrial, or household setting …
beta-Mannobiose
Experimental
Matched Synonyms: … 4-O-β-D-mannopyranosyl-β-D-mannopyranose …
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy …
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy …
2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol
Experimental
Matched Synonyms: … 1,4:3,6-Dianhydro-2,5-bis-O-(3-carbamimidoylphenyl)-D-glucitol …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
Valopicitabine
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched International brands: … Omnatax-O …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [A262995] Examples of third-generation cephalosporins are [ceftriaxone], [cefotaxime], and [ceftazidime ... , and meningitis. …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … FIXACEP OD ... TAXOCEF-O-200MG TABLET ... TAXOCEF-O-400MG TABLET …
Hydrocortisone acetate
Approved
Vet approved
Matched Synonyms: … 21-O-acetylcortisol …
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Proctosone Ont ... Ophthocort Ont ... Sopamycetin/hc Ont …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... Rectocort Ont ... Cortamed Ont 25 mg/g …
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Proctosone Ont ... Ophthocort Ont ... Sopamycetin/hc Ont …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... Rectocort Ont ... Cortamed Ont 25 mg/g …
Cefepime
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ... 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Description: … The activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus ... [A249050] The popularity of its third-generation predecessors, its clinical efficacy, and the high prevalence ... Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1 g/vial ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 g/vial …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Description: … The activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus ... [A249050] The popularity of its third-generation predecessors, its clinical efficacy, and the high prevalence ... Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1 g/vial ... CEFEPIME KABI POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 g/vial …
Uridine triacetate
Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Synonyms: … Tri-O-acetyluridine ... 2',3',5'-tri-O-acetyluridine …
Matched Description: … When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites ... Normally, FdUMP inhibits thymidylate synthase required for thymidine synthesis and DNA replication and ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). …
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …
Matched Description: … When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites ... Normally, FdUMP inhibits thymidylate synthase required for thymidine synthesis and DNA replication and ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). …
Matched Categories: … Alimentary Tract and Metabolism ... Nucleic Acids, Nucleotides, and Nucleosides ... Various Alimentary Tract and Metabolism Products …
Trisaccharide A
Investigational
Matched Synonyms: … 3-o-(2-acetamido-2-deoxy-.alpha.-d-galactopyranosyl)-2-o-(.alpha.-l-fucopyranosyl)-d-galactose …
Matched Iupac: … 3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}oxan-3-yl]acetamide ... N-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(2R,3S,4S,5R)-4,5,6-trihydroxy-1-oxo-2-{[(2S, …
Matched Iupac: … 3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}oxan-3-yl]acetamide ... N-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(2R,3S,4S,5R)-4,5,6-trihydroxy-1-oxo-2-{[(2S, …
Ondansetron
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Iupac: … 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one …
Matched Description: … ondansetron has demonstrated a long history of use and efficacy. ... Commonly formulated as oral tablets, orally disintegrating tablets (ODT), and injections, and available ... It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including …
Matched Categories: … Antiemetics and Antinauseants ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …
Matched Description: … ondansetron has demonstrated a long history of use and efficacy. ... Commonly formulated as oral tablets, orally disintegrating tablets (ODT), and injections, and available ... It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including …
Matched Categories: … Antiemetics and Antinauseants ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …
Guanosine-2'-monophosphate
Experimental
Matched Synonyms: … 2'-O-phosphoguanosine …
Matched Iupac: … {[(2R,3R,4R,5R)-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … {[(2R,3R,4R,5R)-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
2,3-di-O-phytanyl-sn-glycerol
Experimental
Matched Synonyms: … 2,3-Di-O-phytanyl-sn-glycerol …
Matched Name: … 2,3-di-O-phytanyl-sn-glycerol …
Matched Iupac: … (2R)-2,3-bis({[(3R,7R,11R)-3,7,11,15-tetramethylhexadecyl]oxy})propan-1-ol …
Matched Name: … 2,3-di-O-phytanyl-sn-glycerol …
Matched Iupac: … (2R)-2,3-bis({[(3R,7R,11R)-3,7,11,15-tetramethylhexadecyl]oxy})propan-1-ol …
Displaying drugs 451 - 475 of 724 in total