Did you mean bitopertin of rp 493838 of r 18 of ビトペルチン?
Displaying drugs 451 - 475 of 9610 in total
Propofol
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … using a combination of medications. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia ... IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained …
Rumex obtusifolius pollen
Rumex obtusifolius pollen is the pollen of the Rumex obtusifolius plant. Rumex obtusifolius pollen is mainly used in allergenic testing.
Approved
Matched Description: … Rumex obtusifolius pollen is the pollen of the Rumex obtusifolius plant. …
Curcuma aromatica root oil
Curcuma aromatica root oil is obtained from the roots of Curcuma aromatica, or more commonly called wild tumeric, via steamed distillation. Curcuma aromatica belongs to the family Zingiberaceae. The wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and color. The major constituents...
Approved
Matched Description: … Curcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called ... The major constituents of Curcuma aromatica root oil are reported to be camphor, curzerenone, α-turmerone …
Prednisone
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Categories: … CHOP-R chemotherapy regimen …
Moroctocog alfa
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then ... Unfortunately, purification of protein from human plasma carries an increased risk of transmission of ... Congenital loss or deficiency of Factor VIII results in the physiologic impairment of the coagulation …
Bexagliflozin
Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor.[A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge. SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such as SGLT1, SGLT2 is...
Approved
Investigational
Matched Description: … urinary glucose excretion, which reduces blood glucose levels independently of insulin sensitivity. ... [A256413] SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such ... [A256408] By inhibiting SGLT2, bexagliflozin reduces renal reabsorption of filtered glucose and increases …
Etelcalcetide
Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Description: … Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism ( ... Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing …
Treprostinil
Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Description: … Treprostinil is a stable tricyclic analogue of prostacyclin[A248770] that promotes the vasodilation of ... that significantly increases patients' quality of life. ... The first generic form of treprostinil became available in 2019.[A248775] …
Cimetidine
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … Cimetidine has a range of pharmacological actions. ... It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Beta carotene
Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Description: … [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. ... The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. ... Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene …
Maralixibat
Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like odevixibat.[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and...
Approved
Investigational
Matched Description: … [A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients ... [A239249] No clinical trials have been performed to assess the efficacy of these treatments for cholestatic ... Products for Human Use (CHMP) recommended maralixibat be granted marketing authorization for the treatment of …
Saxagliptin
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Description: … -4 (DPP-4) inhibitor class of drugs. ... Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase …
Argatroban
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Description: … The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who ... anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate ... [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Description: … [L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around ... Febuxostat works by inhibiting the activity of an enzyme that is responsible for the synthesis of uric ... [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of …
Aminocaproic acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Fenoprofen
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Cenobamate
Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures.[A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABAA and inhibits voltage gated sodium channels. Cenobamate was granted FDA approval on 21 November 2019.
Approved
Investigational
Matched Description: … [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively …
Tavaborole
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Description: … ATP-dependent ligation of L-leucine to tRNA(Leu). ... Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, ... a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes …
Aclidinium
Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Approved
Matched Description: … Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease …
Corydalis ambigua tuber
Corydalis ambigua tuber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Bacitracin
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Description: … Bacitracin is a combination of at least 9 bacitracins. ... [A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. ... bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of …
Palovarotene
Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million individuals, is an exceptionally rare genetic disorder. FOP is caused by a gain-of-function mutation in the ACVR1/ALK2 gene which results in progressive heterotopic ossification, a process wherein connective tissues (e.g. skeletal muscle, ligaments, tendons) are replaced...
Approved
Investigational
Matched Description: … ], which are derivatives of [vitamin A]. ... Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million ... [A244920] FOP is caused by a gain-of-function mutation in the ACVR1/ALK2 gene which results in progressive …
Fluconazole
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … The side effect profile of this drug is minimal. ... and superficial fungal infections in a variety of tissues. ... Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic …
Phloxine B
Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets allow patients to visualise areas where more brushing and...
Approved
Displaying drugs 451 - 475 of 9610 in total