Displaying drugs 4726 - 4750 of 10620 in total
CoVac-1
Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein . It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults...
Investigational
Matched Description: … the S-protein[A226588]. ... 1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of ... It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide …
Caroxazone
Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.
Withdrawn
Matched Description: … It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Iopentol
Iopentol is used as a contrast medium.
Experimental
Matched Categories: … Diagnostic Uses of Chemicals …
Meclocycline
Meclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) .
Investigational
Matched Description: … of Oral Mucositis) [L797]. ... Meclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment …
Matched Categories: … Antiinfectives for Treatment of Acne …
Matched Categories: … Antiinfectives for Treatment of Acne …
Dirlotapide
Dirlotapide is a drug employed in the treatment of obesity in dogs. It is marketed by Pfizer and Zoetis under the brand name, Slentrol, and is not intended for human use.
Investigational
Vet approved
Matched Iupac: … N-[(S)-[benzyl(methyl)carbamoyl](phenyl)methyl]-1-methyl-5-[4'-(trifluoromethyl)-[1,1'-biphenyl]-2-amido …
Matched Description: … Dirlotapide is a drug employed in the treatment of obesity in dogs. …
Matched Description: … Dirlotapide is a drug employed in the treatment of obesity in dogs. …
2-Amino-3-[5-(Amino-Carboxy-Methyl)-2,3-Dihydro-Isoxazol-3-Ylsulfanyl]-Propionic Acid
Experimental
Matched Iupac: … (2R)-2-amino-3-{[(3R)-5-[(S)-amino(carboxy)methyl]-2,3-dihydro-1,2-oxazol-3-yl]sulfanyl}propanoic acid …
Nedisertib
Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine and Radiotherapy in Rectal Cancer).
Investigational
Matched Iupac: … (S)-{2-chloro-4-fluoro-5-[7-(morpholin-4-yl)quinazolin-4-yl]phenyl}(6-methoxypyridazin-3-yl)methanol …
Matched Description: … Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine …
Matched Description: … Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine …
Brofaromine
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Gepefrine
Experimental
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
ZSTK-474
ZSTK474 has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Description: … ZSTK474 has been used in trials studying the treatment of Neoplasms. …
Repinotan
Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective properties.
Investigational
Matched Description: … Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective …
Ridaforolimus
Investigational
Matched Categories: … Mammalian target of rapamycin (mTOR) kinase inhibitors …
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
Potent reversible inhibitor of phenylethanolamine N-methyltransferase.
Experimental
Matched Description: … Potent reversible inhibitor of phenylethanolamine N-methyltransferase. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Vabicaserin
Vabicaserin has been used in trials studying the health services research and treatment of Schizophrenia.
Investigational
Matched Description: … Vabicaserin has been used in trials studying the health services research and treatment of Schizophrenia …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
LNP-nCoVsaRNA Vaccine
LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells. The vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in the UK, and jointly...
Investigational
Matched Description: … LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV ... of the vaccine. ... As of July 2020, a clinical trial (COVAC1) is underway (ISRCTN17072692) to test the safety and immunogenicity …
Etesevimab
Etesevimab (LY-CoV016, also known as JS016) is a fully human and recombinant monoclonal antibody that targets the SARS-CoV-2 surface spike protein receptor binding domain.[L16651,L16661] Under the EUA granted in February 2021, etesevimab is used in combination with bamlanivimab to treat mild to moderate COVID-19 in adults and pediatric patients who...
Investigational
Matched Description: … [L40174] The EUA currently allows bamlanivimab and etesevimab for post-exposure prophylaxis of COVID- …
Felcisetrag
Felcisetrag (TD-8954) has been used in trials studying the treatment of Enteral Feeding Intolerance and Gastrointestinal Motility Disorder.
Investigational
Matched Description: … Felcisetrag (TD-8954) has been used in trials studying the treatment of Enteral Feeding Intolerance and …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Fosdevirine
Investigational
Matched Iupac: … (S)-(methyl (2-carbamoyl-5-chloro-1H-indol-3-yl)({3-[(1E)-2-cyanoeth-1-en-1-yl]-5-methylphenyl})phosphinate …
(3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine
Experimental
Matched Iupac: … (2S,3R)-4-{[2-(3,4-dihydroxyphenyl)acetyl]oxy}-2-[(2-formylindolizin-3-yl)amino]-3-methyl-3-[(S)-sulfino …
SGN-30
SGN-30 is an engineered monoclonal antibody (mAb) that reacts with significant affinity to the CD30 antigen, which is highly expressed on a variety of hematologic malignancies as compared to on normal cells. SGN-30 has been shown to induce direct anti-cancer activity towards tumor cells expressing CD30 and is undergoing phase...
Investigational
Matched Description: … ) that reacts with significant affinity to the CD30 antigen, which is highly expressed on a variety of ... with chemotherapy for the treatment of relapsed Hodgkin lymphoma, front-line ALCL and pediatric ALCL ... We are collaborating with the National Cancer Institute (NCI) on three clinical trials of SGN-30 in combination …
Flortaucipir
Flortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
Investigational
Matched Categories: … Diagnostic Uses of Chemicals …
Carfentanil
Carfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known (also the most potent opioid used commercially). Carfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutica which included Paul Janssen. It has...
Illicit
Investigational
Vet approved
Matched Description: … It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl ... , and is one of the most potent opioids known (also the most potent opioid used commercially). ... Carfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Ravidasvir
Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).
Investigational
Matched Description: … is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Categories: … Antivirals for treatment of HCV infections …
Displaying drugs 4726 - 4750 of 10620 in total