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Displaying drugs 26 - 50 of 9328 in total
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Synonyms: … (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo ... (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo ... Imidazo(2,1-B)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … Spontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 …
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Synonyms: … 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Matched Iupac: … 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Mixtures name: … Timpilo 4 ... E-pilo-4 Oph Soln ... E-pilo 4 Ophthalmic Solution …
Matched Products: … PİLOKARSOL % 4 GÖZ DAMLASI, 5 ML ... PILOSED % 4 GOZ DAMLASI, 5 ML ... PILOPTIK %4 STERIL GOZ DAMLASI, 5 ML …
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Synonyms: … Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride …
Matched Iupac: … 4-amino-1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium …
Matched Products: … Dequadin Oral Paint .5% …
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … 3,5,3',5'-Tetraiodo-L-thyronine ... 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine ... O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … /sub>, which is then converted through deiodination (by type I or type II 5′-deiodinases)[A179941] into ... potency of ~1:4 (T4:T3). ... the thyroid gland is no longer able to produce sufficient quantities of the thyroid hormones T4< …
Matched Products: … Levohelm 25 Mikrogramm/5 ml Lösung zum Einnehmen ... Levohelm 50 Mikrogramm/5 ml Lösung zum Einnehmen ... Levohelm 100 Mikrogramm/5 ml Lösung zum Einnehmen …
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Synonyms: … Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)- ... trans-4-((2-Amino-3,5-dibromobencil)amino)ciclohexanol ... trans-4-((2-Amino-3,5-dibromobenzyl)amine)cyclohexanol …
Matched Iupac: … (1r,4r)-4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-ol …
Matched Salts cas: … 23828-92-4
Matched Mixtures name: … AMBROXOL 15 MG+ CLENBUTEROL 10 MCG /5 ML …
Matched Products: … AMBROXOL 30 MG /5 ML ... AMXOL SYRUP 30 mg/5 ml ... AMBROXOL 15 MG / 5 ML …
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Synonyms: … 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline ... 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Salts cas: … 19237-84-4
Matched Products: … Prazosin-5 Tab ... APO-PRAZO TABLET 5 mg ... NOPRES 5 MG TABLET, 30 ADET …
Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK). Its high selectivity has been associated with lower discontinuation rates due to adverse events and a lower incidence of atrial fibrillation. Unlike BTK covalent inhibitors, such as ibrutinib, that bind to the cysteine 481...
Approved
Investigational
Matched Synonyms: … 1h-pyrazole-4-carboxamide, 5-amino-3-(4-(((5-fluoro-2-methoxybenzoyl)amino)methyl)phenyl)-1-((1s)-2,2,2 ... (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1h-pyrazole ... 5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-((2s)-1,1,1-trifluoropropan-2-yl)-1h-pyrazole …
Matched Iupac: … 5-amino-3-(4-{[(5-fluoro-2-methoxyphenyl)formamido]methyl}phenyl)-1-[(2S)-1,1,1-trifluoropropan-2-yl] ... -1H-pyrazole-4-carboxamide …
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Synonyms: … 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide ... 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide ... 4-amino-5-chloro-2-methoxy-N-(β-diethylaminoethyl)benzamide …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Salts cas: … 7232-21-5
Matched Products: … METOCLOPRAMIDA 4 MG/ML GOTAS ... METOCLOPRAMIDA 4 MG / ML GOTAS ... METOCLOPRAMIDE SYRUP 5 mg/5 ml …
Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47. It is a potent vasodilator with reported...
Approved
Investigational
Matched Synonyms: … PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)- ... (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen- ... (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS)­ 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H) …
Matched Iupac: … 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2- …
Matched Products: … DIVODIN 20 MCG/ML I.V İNFÜZYONLUK ÇÖZELTİ, 5 ADET ... PULMOLİN 20 MCG/ML IV İNFÜZYONLUK ÇÖZELTİ, 5 ADET ... ILOPERA 20MCG/ML IV INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL, 5 ADET …
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Synonyms: … 4-(2-benzimidazolyl)thiazole ... 2-(thiazol-4-yl)benzimidazole ... 2-(4-thiazolyl)-1H-benzimidazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death...
Approved
Investigational
Matched Synonyms: … 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine ... 20',20'-difluoro-3',4'-dihydrovinorelbine ... 4'-deoxy-20',20'-difluoro-8'-norvincaleukoblastine …
Matched Iupac: … methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-4-[(1R,12S,14S,16R)-16-(1,1-difluoroethyl)-12-(methoxycarbonyl ... 1,10-diazatetracyclo[12.3.1.0^{3,11}.0^{4,9}]octadeca-3(11),4,6,8-tetraen-12-yl]-12-ethyl-10-hydroxy-5- …
Matched Description: … While these patients have a median survival of approximately 4 months and a poor prognosis [L1396], there …
Matched Salts cas: … 194468-36-5
Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Synonyms: … N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide ... N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Products: … Sufentanil Panpharma 5 Mikrogramm/ml Injektionslösung ... Sufentanil-hameln 5 Mikrogramm/ml Injektions-/Infusionslösung ... Sufentanil Kalceks 5 Mikrogramm/ml Injektions-/Infusionslösung …
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Synonyms: … (+)-4-((S)-α,2,3-trimethylbenzyl)imidazole ... (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole …
Matched Iupac: … 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole …
Matched Products: … Dexmedetomidin Altan 4 Mikrogramm/ml Infusionslösung ... Dexmedetomidin Hikma 4 Mikrogramm/ml Infusionslösung ... PRECEDEX 200 MCG 2 ML 5 FLAKON …
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Synonyms: … 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone ... (−)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone …
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one …
Matched Description: … conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5- ... It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase …
Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. Since it targets the hedgehog signaling pathway, vismodegib...
Approved
Investigational
Matched Synonyms: … 2-chloro-N-(4-chloro-3-pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide ... Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)- …
Matched Iupac: … 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-methanesulfonylbenzamide …
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin ... Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][ ... (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H) …
Matched Iupac: … (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3- …
Matched Salts cas: … 33286-22-5
Matched Products: … FARMABES 5 ... DILTIAZEM 25 MG/5 ML SOLUCIÓN INYECTABLE - 1D1003281000 …
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Synonyms: … 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole …
Matched Iupac: … 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine …
Matched Products: … TIZAN 4 ... โทโนไลท์ 4 ... ทีดาร์ 4 มก. …
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Synonyms: … (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Mixtures name: … XIGDUO XR TABLET 5/1000MG ... XIGDUO XR (TABLETS 5 MG/1000 MG) ... Qtern 5 mg/10 mg Film-Coated Tablets …
Matched Products: … DAPAGLEZE 5 MG FILM KAPLI TABLET, 28 ADET ... Dapagliflozin TAD 5 mg Filmtabletten ... DAPAGLEZE 5 MG FILM KAPLI TABLET, 90 ADET …
A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this...
Approved
Vet approved
Matched Synonyms: … 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine ... 4-butyl-1,2-diphenyl-pyrazolidine-3,5-dione ... 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione …
Matched Iupac: … 4-butyl-1,2-diphenylpyrazolidine-3,5-dione …
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … 4-aminosalicylate ... 4-aminosalicylic acid ... 4-amino-2-hydroxybenzoic acid …
Matched Iupac: … 4-amino-2-hydroxybenzoic acid …
Matched Salts cas: … 133-09-5 ... 6018-19-5
Matched Categories: … 4-aminosalicylic acid …
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 5-methyl-3-phenyl-4-isoxazolyl-penicillin ... (5-methyl-3-phenyl-4-isoxazolyl)penicillin ... 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Approved
Matched Synonyms: … 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole ... 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole ... 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole …
Matched Iupac: … 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole …
Matched Products: … แผ่นแปะอัลเลเซก้า 4 มิลลิกรัม ... EMADİNE %0.05 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … (S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-(S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl ... (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide ... 2,6-dimethoxy-4-sulfanilamidopyrimidine ... N(1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide …
Displaying drugs 26 - 50 of 9328 in total