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Displaying drugs 26 - 50 of 10558 in total
Dexamethasone
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Synonyms: … 16α-Methyl-9α-fluoro-1-dehydrocortisol ... 1-Dehydro-16α-methyl-9α-fluorohydrocortisone ... 16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol …
Matched Iupac: … (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H …
Matched Mixtures name: … . + DEXAMETASONA 1 MG)/1ML ... . + DEXAMETASONA 1 MG)/1ML ... DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML …
Matched Products: … DEKSOFTAN 1 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... ONADRON AMPUL, 1 ADET ... DEXALTIN ORAL PASTE 1 mg/g …
Matched Iupac: … (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H …
Matched Mixtures name: … . + DEXAMETASONA 1 MG)/1ML ... . + DEXAMETASONA 1 MG)/1ML ... DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML …
Matched Products: … DEKSOFTAN 1 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... ONADRON AMPUL, 1 ADET ... DEXALTIN ORAL PASTE 1 mg/g …
Enalapril
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Synonyms: … 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester ... (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline ... (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Afamelanotide
Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating hormone (α-MSH). It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer biological half-life.[A187202,A187205] Afamelanotide is...
Approved
Investigational
Matched Synonyms: … Melanotan 1 ... Melanotan-1 …
Matched Iupac: … (4S)-4-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl ... ]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl …
Matched Categories: … Melanocortin 1 Receptor (MC1-R) Agonists …
Matched Iupac: … (4S)-4-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl ... ]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl …
Matched Categories: … Melanocortin 1 Receptor (MC1-R) Agonists …
Stiripentol
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Synonyms: … 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol ... 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cefoperazone
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinylcarboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl ... (6R,7R)-7-[[2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1- ... -1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure …
Matched Iupac: … 1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... (6R,7R)-7-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido]-3-{[( …
Matched Mixtures name: … SEFBAKTAM 1 GR ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL ... SULZON 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, 1 AMPUL ... SULZON 2G/1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, 1 AMPUL …
Matched Products: … CEFOBID 1 GR FLAKON, 1 ADET ... EKOBID 1 G IM/IV ENJEKSIYONLUK TOZ IÇEREN FLAKON , FLAKON, 1 ADET, 1 AMPUL ... STABIXIN-1 …
Matched Iupac: … 1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... (6R,7R)-7-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido]-3-{[( …
Matched Mixtures name: … SEFBAKTAM 1 GR ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL ... SULZON 1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, 1 AMPUL ... SULZON 2G/1 G IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, 1 AMPUL …
Matched Products: … CEFOBID 1 GR FLAKON, 1 ADET ... EKOBID 1 G IM/IV ENJEKSIYONLUK TOZ IÇEREN FLAKON , FLAKON, 1 ADET, 1 AMPUL ... STABIXIN-1 …
Bupivacaine
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Synonyms: … 1-Butyl-2',6'-pipecoloxylidide ... dl-1-Butyl-2',6'-pipecoloxylidide ... 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide …
Matched Iupac: … 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide …
Matched Mixtures name: … Mlp A-1 ... Pro-C-Dure 1 Kit ... Marcaine 0.5% and Epinephrine 1:200,000 Liq …
Matched Products: … BUPİVON % 0,5 ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... BUSACAİN % 0.5 ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... BUVICAINE %0.5 ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET …
Matched Iupac: … 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide …
Matched Mixtures name: … Mlp A-1 ... Pro-C-Dure 1 Kit ... Marcaine 0.5% and Epinephrine 1:200,000 Liq …
Matched Products: … BUPİVON % 0,5 ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... BUSACAİN % 0.5 ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... BUVICAINE %0.5 ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET …
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Propyl alcohol
A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Approved
Matched Synonyms: … 1-propanol ... 1-proponol …
Matched Iupac: … propan-1-ol …
Matched Iupac: … propan-1-ol …
Cytarabine
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 1-beta-D-Arabinofuranosylcytosine ... Cytosine-1-beta-D-arabinofuranoside ... 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … CYTARABINE DBL 10 ML 1 GR FLAKON, 1 ADET ... CITARABINA INYECTABLE 100 MG/ 1 ML ... CYTU 1000 MG/ 10 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … CYTARABINE DBL 10 ML 1 GR FLAKON, 1 ADET ... CITARABINA INYECTABLE 100 MG/ 1 ML ... CYTU 1000 MG/ 10 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Salts cas: … 1235-82-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Salts cas: … 1235-82-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Eliglustat
Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. In patients with Gaucher disease, the accumulation of glucosylceramide leads to...
Approved
Investigational
Matched Synonyms: … N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide …
Matched Iupac: … N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide …
Matched Description: … Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher ... the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 ... [L41404,A7634] Enzyme replacement continues to be the standard of care for the treatment of type 1 Gaucher …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide …
Matched Description: … Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher ... the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 ... [L41404,A7634] Enzyme replacement continues to be the standard of care for the treatment of type 1 Gaucher …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ritlecitinib
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)- …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Desmopressin
Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Synonyms: … 1-deamino-8-D-arginine vasopressin ... 1-desamino-8-D-arginine vasopressin ... 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin …
Matched Iupac: … (2R)-2-{[(2S)-1-[(4R,7S,10S,13S,16S)-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl …
Matched Description: … analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1- …
Matched Products: … EMOSINT 20 MCG / 1 ML SOLUCION INYECTABLE ... OCTOSTIM 30 MCG/2 ML IV/SC ENJEKSIYON IÇIN ÇÖZELTI IÇEREN AMPUL, 1 ADET …
Matched Iupac: … (2R)-2-{[(2S)-1-[(4R,7S,10S,13S,16S)-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl …
Matched Description: … analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1- …
Matched Products: … EMOSINT 20 MCG / 1 ML SOLUCION INYECTABLE ... OCTOSTIM 30 MCG/2 ML IV/SC ENJEKSIYON IÇIN ÇÖZELTI IÇEREN AMPUL, 1 ADET …
Duloxetine
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Synonyms: … (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DULOXETIN 1 A PHA 30MG HKP ... DULOXETIN 1 A PHA 60MG HKP …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DULOXETIN 1 A PHA 30MG HKP ... DULOXETIN 1 A PHA 60MG HKP …
Isoeugenol
Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by...
Approved
Experimental
Matched Synonyms: … 2-methoxy-4-(prop-1-en-1-yl)phenol ... 1-Hydroxy-2-methoxy-4-propen-1-ylbenzene …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Cinacalcet
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Synonyms: … N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine ... (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine …
Matched Iupac: … [(1R)-1-(naphthalen-1-yl)ethyl]({3-[3-(trifluoromethyl)phenyl]propyl})amine …
Matched Iupac: … [(1R)-1-(naphthalen-1-yl)ethyl]({3-[3-(trifluoromethyl)phenyl]propyl})amine …
Penciclovir
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine ... 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine ... 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine …
Matched Products: … EX-LOVIR % 1 KREM 2 G ... PENSIVIR %1 KREM , 2 G ... PENSIVIR %1 KREM , 5 G …
Matched Products: … EX-LOVIR % 1 KREM 2 G ... PENSIVIR %1 KREM , 2 G ... PENSIVIR %1 KREM , 5 G …
Zuclopenthixol
Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Synonyms: … (Z)-4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Matched Salts cas: … 58045-23-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … SOLUSYON, 1 ML ... CLOPIXOL DEPOT ENJ. 200 MG/ML IM SOLÜSYON, 1 ML …
Matched Iupac: … 2-(4-{3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Matched Salts cas: … 58045-23-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … SOLUSYON, 1 ML ... CLOPIXOL DEPOT ENJ. 200 MG/ML IM SOLÜSYON, 1 ML …
Cefepime
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ... (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Products: … CEFEPIMA 1 G ... ROXIPIME 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 1 ADET ... CEFEPEN INJECTION 1 g …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Products: … CEFEPIMA 1 G ... ROXIPIME 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 1 ADET ... CEFEPEN INJECTION 1 g …
Adagrasib
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. However, the development of KRAS inhibitors has been challenging due to their high affinity for guanosine triphosphate (GTP) and guanosine diphosphate...
Approved
Investigational
Matched Synonyms: … )methoxy)pyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2s)- ... ((2s)-4-(7-(8-chloronaphthalen-1-yl)-2-(((2s)-1- methylpyrrolidin-2-yl)methoxy)-5,6,7,8- tetrahydropyrido ... 2-piperazineacetonitrile, 4-(7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2s)-1-methyl-2-pyrrolidinyl …
Matched Iupac: … 2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4 ... -d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4 ... -d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sulfacytine
Sulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism...
Approved
Matched Synonyms: … 1-ethyl N4-sulfanilylcytosin ... 1-ethyl-N-sulfanilylcytosine …
Matched Iupac: … 4-amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzene-1-sulfonamide …
Matched Iupac: … 4-amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzene-1-sulfonamide …
Potassium cation
Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Synonyms: … potassium(1+) ... potassium(1+) ion …
Matched Iupac: … potassium(1+) ion …
Matched Iupac: … potassium(1+) ion …
Diphenylpyraline
Diphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells. Antihistamines prevent, but do not reverse, responses mediated by histamine alone. Antihistamines antagonize, in varying degrees, most of the pharmacological effects of histamine, including urticaria and pruritus.
Approved
Investigational
Matched Synonyms: … 1-methyl-4-piperidyl benzhydryl ether ... 4-(benzhydryloxy)-1-methylpiperidine ... 1-methyl-4-hydroxypiperidine benzhydryl ether …
Matched Iupac: … 4-(diphenylmethoxy)-1-methylpiperidine …
Matched Description: … Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-(diphenylmethoxy)-1-methylpiperidine …
Matched Description: … Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dipentamethylenethiuram disulfide
Approved
Experimental
Matched Synonyms: … 1-Piperidinethiocarbonyl disulfide ... Bis(1-piperidylthiocarbonyl) disulfide ... Bis(1-piperidylthiocarbonyl)disulfide …
Matched Iupac: … piperidine-1-carbothioylsulfanyl piperidine-1-carbodithioate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … piperidine-1-carbothioylsulfanyl piperidine-1-carbodithioate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tesamorelin
Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Synonyms: … GHRH(1-44) ... N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet) …
Displaying drugs 26 - 50 of 10558 in total