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Displaying drugs 476 - 500 of 693 in total

Levomefolic acid

Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Description: … It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the ... regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form …
Matched Mixtures name: … Levomefolate Calcium and Algal ... Levomefolate Calcium and Algal ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium …
Matched Salts name: … Levomefolate calcium …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins …
Matched Products: … L-Methylfolate Calcium …

Omfiloctocog alfa

Omfiloctocog alfa is under investigation in clinical trial NCT03947567 (Safety and Efficacy of Long-term Treatment With SCT800 in Previously Treated Hemophilia a Patients.).
Investigational
Matched Synonyms: … 1639)-SEQUENCE: SINGLE-CHAIN RECOMBINANT FVIII COMPOSED OF DOMAINS A1-A1-A2-A2 (1-740), THE B-DOMAIN N-AND …
Matched Description: … Omfiloctocog alfa is under investigation in clinical trial NCT03947567 (Safety and Efficacy of Long-term …

Acamprosate

Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Description: … Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... economic consequences resulting from accidents, violence, incarceration, decreased productivity, and ... It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783] …
Matched Salts name: … Acamprosate calcium …
Matched Categories: … OAT1/SLC22A6 Substrates ... Sulfur Acids ... Sulfur Compounds …
Matched Products: … Acamprosate Calcium …

MEM 1003

MEM 10003 was under investigation in clinical trial NCT00257673 (Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease) for the treatment of Alzheimer's Disease.
Investigational
Matched Synonyms: … VOLTAGE-GATED CALCIUM CHANNEL SUBUNIT ALPHA CAV1.2 ... VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C ... CALCIUM CHANNEL, L TYPE, ALPHA-1 POLYPEPTIDE, ISOFORM 1, CARDIAC MUSCLE …
Matched Description: … MEM 10003 was under investigation in clinical trial NCT00257673 (Safety and Efficacy of MEM 1003 Versus …

Bazlitoran

Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Avena sativa flowering top

Avena sativa flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Oat Flowering Top …

Englumafusp alfa

Englumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/refractory B-cell Non-hodgkin's Lymphoma).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa anti-(human B-lymphocyte antigen CD19) modified heterodimer where the heavy and …
Matched Description: … under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and ... Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination …

Tolevamer

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Description: … It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines ... It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among …
Matched Salts name: … Tolevamer calcium …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Sulfur Acids ... Sulfur Compounds …
Matched Products: … Resonium Calcium ... CALCIUM POLYSTYRENE SULFONATE ... Jamp Calcium Polystyrene Sulfonate …

Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and ... It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Categories: … OAT1/SLC22A6 inhibitors ... OAT3/SLC22A8 Inhibitors ... OAT3/SLC22A8 Substrates ... Alimentary Tract and Metabolism ... tetracycline and oleandomycin …
Matched Products: … MeaStem First Aid and Antibiotic …

(-)-menthol 1-propylene glycol carbonate

Experimental
Matched Synonyms: … (-)-menthol (+/-)-1-propylene glycol carbonate ... Fema no. 3806, 1-propylene glycol carbonate ... 2-hydroxypropyl ((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) carbonate …
Matched Name: … (-)-menthol 1-propylene glycol carbonate …

Rauwolfia serpentina root

Rauwolfia (Rauwolfia serpentina), also spelled ravolphia, is a medicinal plant in the milkweed family. The root of the plant is ground into a powder or sold in tablets or capsules. It is a compound commonly used in Asian medicine, which includes traditional Ayurvedic medicine native to India. The active ingredients...
Investigational
Matched Synonyms: … Rauwolfia root ... Rauvolfia serpentina root …
Matched Name: … Rauwolfia serpentina root …
Matched Description: … complete Rauwolfia plants and shows survival and unaltered biosynthetic potential during storage at ... The root of the plant is ground into a powder or sold in tablets or capsules. ... , although the primary psychoactive components appear to be reserpine, rescinnamine, and deserpidine …
Matched Categories: … rauwolfia alkaloids, whole root and diuretics …

Calcium fluoride

Experimental
Matched Name: … Calcium fluoride …
Matched Categories: … Calcium Compounds …

Etevritamab

Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND …

Fazpilodemab

Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …

Ketotifen

Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and …
Matched Categories: … Decongestants and Antiallergics ... Sulfur Compounds …
Matched Products: … Up and Up Eye Itch Relief …

Atropine

Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched Description: … , subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. ... It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active ... [A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous …
Matched Mixtures name: … ATNAA atropine and pralidoxime chloride Auto-Injector ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Categories: … Alimentary Tract and Metabolism ... pralidoxime and atropine ... Mydriatics and Cycloplegics ... Belladonna and Derivatives, Plain ... atropine and psycholeptics …
Matched Products: … ATROPINE SULFAT IE AMPUL 1 MG/ML, 10 ADET ... ATROPIN SULFAT BIOFARMA 1MG/1 ML 100 AMPUL ... ATROPIN SULFAT BIOFARMA 0,5MG/1ML 100 AMPUL …

Fosamprenavir

Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Approved
Matched Salts name: … Fosamprenavir calcium …
Matched Categories: … Amprenavir and Prodrugs ... Sulfur Compounds …
Matched Products: … Fosamprenavir Calcium …

Carbamoylcholine

Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects. Carbamoylcholine was granted FDA approval on 28 September 1972.
Approved
Matched Synonyms: … Choline carbamate …
Matched Iupac: … 2-(trimethylazaniumyl)ethyl carbamate …
Matched Description: … Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and …
Matched Categories: … Antiglaucoma Preparations and Miotics …

Streptomycin

Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid ... OAT1/SLC22A6 inhibitors …
Matched Products: … KRISTALIZE STREPTOMISIN SULFAT ... STREPTOMYCIN SULFAT ENJEKTABL FLAKON, 1 ADET …

Calcium silicate

Experimental
Matched Name: … Calcium silicate …
Matched Iupac: … calcium ditrihydrogen silicate …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium Compounds ... calcium silicate …

Glycyrrhiza uralensis root

Experimental
Matched Name: … Glycyrrhiza uralensis root …

Ipecac

Ipecac is obtained from the plant Cephaelis ipecacuanha and contains a number of emetic alkaloids including emetine and cephaeline. Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. The FDA does not have currently any approved product containing ipecac, however, ipecac as an...
Approved
Withdrawn
Matched Description: … emetine and cephaeline. ... Ipecac is obtained from the plant _Cephaelis ipecacuanha_ and contains a number of emetic alkaloids including …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Ipecac roots …

Sodium phosphate tribasic dodecahydrate

Experimental
Matched Synonyms: … Phosphoric acid, trisodium salt, dodeahydrate ... Phosphoric acid, trisodium salt, dodecahydrate …
Matched Categories: … Phosphoric Acids ... Phosphorus Acids ... Phosphorus Compounds …

Chlorphenesin carbamate

Approved
Vet approved
Withdrawn
Matched Synonyms: … Chlorphenesin carbamate ... 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate ... 3-(4-chlorophenoxy)-1,2-propanediol-1-carbamate …
Matched Name: … Chlorphenesin carbamate …
Matched Iupac: … 3-(4-chlorophenoxy)-2-hydroxypropyl carbamate …

Mephenesin carbamate

Investigational
Matched Synonyms: … 3-(2-methylphenoxy)-1,2-propanediol 1-carbamate …
Matched Name: … Mephenesin carbamate …
Displaying drugs 476 - 500 of 693 in total