Displaying drugs 476 - 500 of 15249 in total
Tannic acid
Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine....
Approved
Matched Description: … Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria ... It acts as a weak acid. ... Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. …
Matched Mixtures name: … NEO-EMOCICATROL …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … NEO-EMOCICATROL …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Hydroxyethyl cellulose
Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as...
Approved
Matched Description: … It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its ... Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming ... and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Doxercalciferol
Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment...
Approved
Matched Iupac: … ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol ... 3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4- …
Matched Description: … Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form ... with Stage 3 or Stage 4 chronic kidney disease. ... by Catalent Pharma Solutions, Inc. …
Matched Description: … Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form ... with Stage 3 or Stage 4 chronic kidney disease. ... by Catalent Pharma Solutions, Inc. …
Sodium acetate
Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Description: … Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. ... Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in ... It can be used also in metabolic acidosis and for urine alkalinization. …
Matched Salts cas: … 6131-90-4 …
Matched Mixtures name: … GELOFUSINE® ISO 4% ... Plasma-Lyte A ... PLASMA-LYTE A INJECTION …
Matched Salts cas: … 6131-90-4 …
Matched Mixtures name: … GELOFUSINE® ISO 4% ... Plasma-Lyte A ... PLASMA-LYTE A INJECTION …
Icodextrin
Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport...
Approved
Investigational
Matched Description: … It is injected as a solution into the peritoneal cavity. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Etilefrine
Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Approved
Withdrawn
Matched Description: … It has been used as a vasoconstrictor agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg …
Matched Description: … Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg …
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … It is a more commonly prescribed drug in Europe. ... In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, [DB00586], via chemical ... It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional …
Antilymphocyte immunoglobulin (horse)
Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Description: … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune ... (rabbit, horse, or pig) and in the type of antigen product used to produce immunoglobulin (thymocytes ... effect in these conditions. …
Brigatinib
Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Iupac: … 5-chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl] …
Matched Description: … , which is a pivotal player in the transformation of susceptible lung parenchyma. ... [A31313] Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company ... It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene …
Matched Categories: … Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … , which is a pivotal player in the transformation of susceptible lung parenchyma. ... [A31313] Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company ... It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene …
Matched Categories: … Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Sodium phosphate, monobasic
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Description: … Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine ... It usually results in a bowel movement after 30 minutes to 6 hours. …
Matched Mixtures name: … NUTRIFLEX PLUS IN 1000ML TWIN FLEX ... NUTRIFLEX PLUS IN 2000ML TWIN FLEX ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) …
Matched Mixtures name: … NUTRIFLEX PLUS IN 1000ML TWIN FLEX ... NUTRIFLEX PLUS IN 2000ML TWIN FLEX ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) …
Human thrombin
Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass...
Approved
Matched Description: … Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen ... In particular, while human thrombin products are made from pooled human source plasma, recombinant thrombin ... is a human coagulation protein produced via recombinant DNA technology from a genetically modified Chinese …
Padeliporfin
Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies. Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a focal treatment for localized prostate cancer. It aims to destroy only cancerous lesions of the prostate, rather than ablating the entire prostate gland. Padeliporfin...
Approved
Experimental
Matched Iupac: … palladium(2+) (4S,5S,14R,15R)-10-acetyl-4-(2-carboxyethyl)-15-ethyl-2-(2-methoxy-2-oxoethyl)-5,9,14,19 …
Matched Description: … of low-risk prostate cancer in adults meeting certain clinical criteria. ... [A244699] Padeliporfin was first approved by the European Commission on November 10, 2017, for the treatment ... [A244559] Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Sensitizers Used in Photodynamic/radiation Therapy …
Matched Description: … of low-risk prostate cancer in adults meeting certain clinical criteria. ... [A244699] Padeliporfin was first approved by the European Commission on November 10, 2017, for the treatment ... [A244559] Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Sensitizers Used in Photodynamic/radiation Therapy …
Patent Blue
Patent blue is aniline dye and it is one of the most common dyes used. It is a sodium or calcium salt of diethylammonium hydroxide inner salt. It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1-ylidene)diethylammonium hydroxide. Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979....
Approved
Matched Iupac: … 4-{[4-(diethylamino)phenyl](5-hydroxy-2,4-disulfophenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1- …
Matched Description: … [A32573] It is a sodium or calcium salt of diethylammonium hydroxide inner salt. ... Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979. ... [A32574] It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene …
Matched Salts cas: … 20262-76-4 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … [A32573] It is a sodium or calcium salt of diethylammonium hydroxide inner salt. ... Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979. ... [A32574] It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene …
Matched Salts cas: … 20262-76-4 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ceftobiprole
Ceftobiprole is a fifth-generation semisynthetic cephalosporin antibacterial which is available commercially as the prodrug ceftobiprole medocaril. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA).
The EMA's Committee for Medicinal Products for Human Use (CHMP)...
Approved
Investigational
Matched Description: … Ceftobiprole is a fifth-generation semisynthetic cephalosporin antibacterial which is available commercially ... Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative ... The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole …
Ziprasidone
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Iupac: … 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one …
Matched Description: … [A190525] These mental illnesses can often be accompanied by comorbidities such as depression and substance ... [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower ... treat manic episodes in bipolar disorder although the mechanism of action is unknown. …
Matched Description: … [A190525] These mental illnesses can often be accompanied by comorbidities such as depression and substance ... [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower ... treat manic episodes in bipolar disorder although the mechanism of action is unknown. …
Varenicline
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … Varenicline is a prescription medication used to treat smoking addiction. ... A full agonism was displayed on alpha7-receptors.
On March 9, 2015, the U.S. ... Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine …
Matched Categories: … Drugs Used in Addictive Disorders ... Drugs Used in Nicotine Dependence …
Matched Categories: … Drugs Used in Addictive Disorders ... Drugs Used in Nicotine Dependence …
Brilliant green cation
Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.
Approved
Vet approved
Matched Iupac: … 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium …
Matched Description: … Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to ... Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic …
Matched Salts cas: … 633-03-4 …
Matched Mixtures name: … Kerr 100 Triple Dye Dispos-A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to ... Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic …
Matched Salts cas: … 633-03-4 …
Matched Mixtures name: … Kerr 100 Triple Dye Dispos-A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Drometrizole trisiloxane
Drometrizole trisiloxane is a photostable UVA and UVB light filter [A33069, L2780, L2781, L2782, L2783, F81]. The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and Japan, among other countries....
Approved
Matched Iupac: … -4-yl)propyl]phenol ... 2-(2H-1,2,3-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-(2,2,4,6,6-pentamethyl-3,5-dioxa-2,4,6-trisilaheptan …
Matched Description: … The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens ... Drometrizole trisiloxane is a photostable UVA and UVB light filter [A33069, L2780, L2781, L2782, L2783 ... with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and …
Matched Mixtures name: … Anthelios XL Melt-IN Cream …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens ... Drometrizole trisiloxane is a photostable UVA and UVB light filter [A33069, L2780, L2781, L2782, L2783 ... with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and …
Matched Mixtures name: … Anthelios XL Melt-IN Cream …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Polyethylene glycol 400
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788 ... It is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility ... a low-level toxicity. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Polatuzumab vedotin
Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Matched Description: … Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was approved by ... Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E ... [L6658] The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody …
Desonide
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Description: … A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. …
Matched Mixtures name: … PRECORT-A KREM ... PRECORT-A POMAD ... PREDNOL-A 30 GR KREM …
Matched Mixtures name: … PRECORT-A KREM ... PRECORT-A POMAD ... PREDNOL-A 30 GR KREM …
Turpentine
Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Description: … It is used as a solvent and base material in organic synthesis reactions. ... Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Chromium picolinate
Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. Chromium ions are shown to regulate...
Approved
Matched Description: … Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with ... Chromium ions are shown to regulate insulin by promoting glucose utilization and increasing the sensitivity ... Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 476 - 500 of 15249 in total