Displaying drugs 501 - 525 of 682 in total
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... short consensus domains of human complement receptor 1 (CR1), manufactured in recombinant bacteria and …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... short consensus domains of human complement receptor 1 (CR1), manufactured in recombinant bacteria and …
Trofinetide
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid …
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Human blood group H type 1 trisaccharide
Experimental
Matched Synonyms: … H type I ... H type I epitope ... H type I trisaccharide …
Matched Name: … Human blood group H type 1 trisaccharide …
Matched Name: … Human blood group H type 1 trisaccharide …
Bazlitoran
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
2-[2-(2-Cyclohexyl-2-guanidino-acetylamino)-acetylamino]-N-(3-mercapto-propyl)-propionamide
Experimental
Matched Synonyms: … N-{(2R)-2-Cyclohexyl-2-[(diaminomethylene)amino]acetyl}glycyl-N-(3-sulfanylpropyl)-L-alaninamide …
AD-114
Investigational
Matched Synonyms: … Human single domain antibody-like protein inhibitor of the chemokine receptor type 4 …
Acemetacin
Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin. It was developed by...
Approved
Investigational
Matched Synonyms: … indometacin glycolic ester ... indomethacin glycolic ester …
Matched Description: … Merck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on ... the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Description: … Merck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on ... the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Haemophilus influenzae b polysaccharide-tetanus conjugate
Approved
Matched Synonyms: … Haemophilus influenzae type b polysaccharide conjugated to tetanus protein ... Haemophilus influenzae type b polysaccharide conjugated to the tetanus protein …
Glycopyrronium
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Description: … [L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists. ... found that glycopyrronium could also be used for reducing sweat gland,[L4755] oral,[L33140] airway, and ... L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and glycopyrronium bromide ... indacaterol and glycopyrronium bromide ... glycopyrronium bromide and psycholeptics ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … GLYCO-P …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and glycopyrronium bromide ... indacaterol and glycopyrronium bromide ... glycopyrronium bromide and psycholeptics ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … GLYCO-P …
BCG vaccine
BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.
Approved
Investigational
Matched Synonyms: … Bacillus calmette-guerin live antigen, unspecified substrain …
Matched Description: … investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
S,R-Warfarin alcohol
Experimental
Matched Name: … S,R-Warfarin alcohol …
Matched Categories: … Warfarin and isomers …
Matched Categories: … Warfarin and isomers …
2,3-di-O-phytanyl-sn-glycerol
Experimental
Matched Synonyms: … 2,3-diphytanyl-sn-glycerol ... 2,3-Di-O-phytanyl-sn-glycerol …
Matched Name: … 2,3-di-O-phytanyl-sn-glycerol …
Matched Categories: … Alcohols ... Sugar Alcohols ... Triose Sugar Alcohols …
Matched Name: … 2,3-di-O-phytanyl-sn-glycerol …
Matched Categories: … Alcohols ... Sugar Alcohols ... Triose Sugar Alcohols …
Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a vaccine for intramuscular injection used in the prevention of invasive disease caused by Haemophilus influenzae type b. H. influenzae is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis. The vaccine contains the Haemophilus...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate …
Matched Name: … Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Description: … The toxoid antigen is purified and toxin-inactivated. ... *H. influenzae* is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis ... Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is …
Matched Name: … Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Description: … The toxoid antigen is purified and toxin-inactivated. ... *H. influenzae* is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis ... Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is …
Mepivacaine
A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Description: … It is indicated for infiltration, nerve block, and epidural anesthesia. ... Mepivacaine is effective topically only in large doses and therefore should not be used by this route …
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin ... CARBOSEN CON ADRENALINA ... CARBOSEN CON ADRENALINA …
Matched Products: … CARBOSEN …
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin ... CARBOSEN CON ADRENALINA ... CARBOSEN CON ADRENALINA …
Matched Products: … CARBOSEN …
Sodium glycerophosphate
Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Approved
Matched Synonyms: … Disodium glycerol phosphate …
Matched Description: … Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. …
Matched Mixtures name: … Vitamin and Mineral Supplement - Liq ... Hemarexin Liquid and Drinkable Ampoules …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Alcohols ... Sugar Alcohols ... Triose Sugar Alcohols …
Matched Description: … Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. …
Matched Mixtures name: … Vitamin and Mineral Supplement - Liq ... Hemarexin Liquid and Drinkable Ampoules …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Alcohols ... Sugar Alcohols ... Triose Sugar Alcohols …
N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine
Experimental
Matched Synonyms: … Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanyl-D-alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and …
Matched Mixtures name: … Lip And Hand Camellia ... Lip And Hand Wild Rose ... Lip And Hand Shea Butter …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment …
Matched Mixtures name: … Lip And Hand Camellia ... Lip And Hand Wild Rose ... Lip And Hand Shea Butter …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment …
Glymidine
Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched International brands: … Glycanol …
Matched Description: … Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and ... appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and ... ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and ... appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and ... ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Ketotifen
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief …
Etevritamab
Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND …
Fazpilodemab
Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and ... Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and ... Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis …
R,S-Warfarin alcohol
Experimental
Matched Name: … R,S-Warfarin alcohol …
Matched Categories: … Warfarin and isomers …
Matched Categories: … Warfarin and isomers …
Glycerol Tribenzoate
Investigational
Matched Synonyms: … Glycerol, tribenzoate …
Matched Name: … Glycerol Tribenzoate …
Matched Name: … Glycerol Tribenzoate …
Displaying drugs 501 - 525 of 682 in total