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Displaying drugs 501 - 525 of 762 in total

Opipramol

Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Investigational
Matched Description: … been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and …
Matched Products: … OPIPRAMOL HEXAL 50MG ... OPIPRAMOL HEXAL 100MG ... OPIPRAMOL HEXAL 150MG …

Xipamide

Experimental
Matched Products: … XIPAMID HEXAL 10MG ... XIPAMID HEXAL 20MG ... XIPAMID HEXAL 40MG …

Dalosirvat

Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia).
Investigational
Matched Synonyms: … 1-(2,3-dihydro-benzo(1,4)dioxin-6-yl)-4-phenyl-butane-1,4-dione …
Matched Description: … Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and …

Carbimazole

An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Approved
Investigational
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CARBIMAZOL 5MG HEXAL ... CARBIMAZOL 10MG HEXAL …

5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE

Experimental
Matched Name: … 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE …

Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Mixtures name: … RAMIPRIL HEXAL PL PIR5/6MG ... RAMIPRIL HEXAL PL PIR5/6MG ... RAMIPRIL HEXAL PL PIR5/6MG …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … PIRETANID HEXAL 3MG ... PIRETANID HEXAL 6MG …

Pergolide

Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome....
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine ... The drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Products: … PERGOLID HEXAL 1MG ... PERGOLID HEXAL 0.25MG …

Azathioprine

Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and ... A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … AZATIOPRINA HEXAL ... AZATHIOPRIN HEXAL 75MG ... AZATHIOPRIN HEXAL 100MG …

Ramipril

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Mixtures name: … RAMIPRIL HEXAL PL AM 5/5 ... RAMIPRIL HEXAL PL AM 5/5 ... RAMIPRIL HEXAL PL AM 5/5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... ramipril and amlodipine ... ramipril and diuretics …
Matched Products: … RAMIPRIL HEXAL ... RAMIPRIL HEXAL AG ... RAMIPRIL HEXAL 5MG …

Moclobemide

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide ... is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA ... Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than …
Matched Categories: … Benzamides and benzamide derivatives ... Benzoates …
Matched Products: … MOCLOBEMID HEXAL 150MG ... MOCLOBEMID HEXAL 300MG ... MOCLOBEMIDE HEXAL TABLET 150mg …

Mirtazapine

Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Description: … prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. ... symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and …
Matched Products: … MIRTAZAPINA HEXAL ... MIRTAZAPINA HEXAL AG ... MIRTAZAPIN HEXAL 15MG …

Methimazole

Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now ... potent than the other major antithyroid thionamide used in North America, [propylthiouracil],[L8339] and ... metabolite of the pro-drug [carbimazole], which is an antithyroid medication used in the United Kingdom and …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … THIAMAZOL 5MG HEXAL ... THIAMAZOL 10MG HEXAL ... THIAMAZOL 20MG HEXAL …

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... Due to these modifications, it presents a very high potency and comparable side effect profile to the ... hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … HYDROMORPHON HEXAL 4MG ... HYDROMORPHON HEXAL 8MG ... HYDROMORPHON HEXAL 16MG …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … NIMODIPINA HEXAL ... NIMODIPIN HEXAL 30MG ... Nimodipine HEXAL® 30 mg Film-coated Tablet …

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Description: … , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. ... Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension …
Matched Categories: … Alpha and Beta Blocking Agents ... carvedilol and ivabradine ... Calcium-Regulating Hormones and Agents …
Matched Products: … CARVEDILOLO HEXAL ... CARVEDILOL HEXAL 25MG ... CARVEDILOL HEXAL 50MG …

Etavopivat

Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and …
Matched Categories: … moxonidine and diuretics …
Matched Products: … MOXONIDIN HEXAL 0.2MG FILM ... MOXONIDIN HEXAL 0.3MG FILM ... MOXONIDIN HEXAL 0.4MG FILM …

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MTX 10 HEXAL INJEKT ... MTX 15MG HEXAL INJEKT ... MTX 7.5MG HEXAL INJEKT …

Clopidogrel

Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … HEXYR ... CLOPIDOGREL HEXAL ... Clopidogrel Hexal …

Tiapride

Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
Investigational
Matched Iupac: … N-[2-(diethylamino)ethyl]-5-methanesulfonyl-2-methoxybenzamide …
Matched Description: … Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain. …
Matched Categories: … Benzamides and benzamide derivatives ... Benzoates …
Matched Products: … TIAPRID HEXAL 100MG ... TIAPRID HEXAL 200MG …

Benazepril

Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and …
Matched Mixtures name: … Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... benazepril and diuretics ... benazepril and amlodipine …
Matched Products: … BENAZEPRIL HEXAL 5MG ... BENAZEPRIL HEXAL 10MG …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. ... A14720] Citalopram enhances serotonergic transmission through the inhibition of serotonin reuptake, and …
Matched Products: … CITALOPRAM HEXAL ... CITALOPRAM HEXAL AG ... CITALOPRAM HEXAL 10MG …

Glimepiride

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Description: … long-term microvascular and macrovascular complications that lead to co-morbidities and mortalities. ... worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and ... present,[A177715] as they work by stimulating the release of insulin from the pancreatic beta cells and …
Matched Mixtures name: … Pioglitazone and Glimepiride ... Pioglitazone and Glimepiride ... Pioglitazone hydrochloride and glimepiride …
Matched Categories: … Alimentary Tract and Metabolism ... glimepiride and rosiglitazone ... glimepiride and pioglitazone …
Matched Products: … GLIMEPIRIDE HEXAL ... GLIMEPIRID HEXAL 1MG ... GLIMEPIRID HEXAL 2MG …

Amisulpride

Amisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine D2 and D3 receptors. As an antipsychotic agent, amisulpride alleviates both positive and negative symptoms of schizophrenia, and it exhibits antidepressant properties in patients with psychiatric disorders, dysthymia, and major depression. Amisulpride predominantly works in...
Approved
Investigational
Matched Description: … D2 and D3 receptors. ... , and it exhibits antidepressant properties in patients with psychiatric disorders, dysthymia, and major ... Amisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine …
Matched Categories: … Benzamides and benzamide derivatives ... Benzoates …
Matched Products: … AMISULPRID HEXAL 50MG ... AMISULPRID HEXAL 100MG ... AMISULPRID HEXAL 200MG …

Fluvastatin

Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Description: … levels and prevent cardiovascular disease. ... Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol ... Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. …
Matched Products: … FLUVASTATIN HEXAL 20MG ... FLUVASTATIN HEXAL 40MG ... FLUVASTATIN HEXAL 80MG RET …
Displaying drugs 501 - 525 of 762 in total