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Displaying drugs 501 - 525 of 702 in total
Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Synonyms: … (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone …
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
Matched Description: … Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness ... The intranasal route of administration for this drug allows for easy administration and a fast onset ... disorder who have not experienced an improvement in symptoms despite treatment with various medications and
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine ... O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine …
Matched Description: … [F4633] T4 and T3 act on nearly every cell of the body, but have a particularly ... the thyroid hormones T4 (tetraiodothyronine or thyroxine) and T3 (triiodothyronine ... the physiological effects of the thyroid hormones; T4 and T3 have a relative potency …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... levothyroxine sodium and iodine compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Mixtures name: … Systane Day and Night Value Pack ... Systane Day and Night Value Pack ... Foster and Thrive Long Lasting Lubricant Eye Drops …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Eyelash and Eyebrow Lengthener …
Experimental
Matched Name: … O-(N-acetyl-alpha-D-galactosaminyl)-L-serine …
Matched Iupac: … (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic …
Experimental
Matched Name: … 2''-O-[N-(3-(aminopropyl)2-aminoethyl]paromomycin …
Matched Iupac: … }-6-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol ... [(1R,2R,3S,5R,6S)-3,5-diamino-2-{[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER THE CONTROL OF ... AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND
Matched Description: … ., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa …
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, ... nasal and nasopharyngeal mucosa. …
Matched Mixtures name: … Rohto All-In-One ... Care One Eye Drops Seasonal Relief ... Up and Up Ultra Itchy Relief …
Matched Categories: … Decongestants and Antiallergics ... Compounds used in a research, industrial, or household setting …
Matched Products: … OPHTA OFT %0,05 5 ML DAMLA ... Foster and Thrive Original Formula Eye Drops ... Walgreens Eye Drops Original 15mL and twin pack …
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … Agaliya oil ... Castor oil ... Castorbean oil
Matched Name: … Castor oil
Matched Description: … Castor oil was mainly used in the manufacturing of soaps, lubricants, and coatings [A31170]. ... It can also be found in hard candies as a release agent and anti-sticking agent, or supplementary vitamins ... Due to its renewability and high versatility in addition to being the only commercial source of a hydroxylated …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP ... Oil
Matched Categories: … castor oil ... Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil ... Castor Oil ... Oil
Investigational
Matched Synonyms: … cd3 epsilon chain (cd3e) on t-cells ... immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma …
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and
Matched Categories: … Skin and Mucous Membrane Agents ... Arteriolar Smooth Muscle, Agents Acting On
Matched Products: … Hair essential oil ... Up and Up Minoxidil ... Up and Up minoxidil …
Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
Experimental
Matched Synonyms: … Guanosine 5'-O-(3-thiotriphosphate) …
Matched Iupac: … )phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonothioic acid ... ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes ... A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.
Investigational
Nutraceutical
Matched Description: … Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which ... can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties …
Matched Mixtures name: … Shine Oramin Natural Korean Ginseng + Royal Jelly with Multivitamins and Minerals. ... Blood Care Honzo Seika Chinese Herbal Aroma Oil ... Blood Care Honzo Seika Chinese Herbal Aroma Oil
Matched Categories: … Herbs and Natural Products …
Matched Products: … Power / Vacsu Power (Dynamic and Powerful 99 year life) ... Stem Cell Extract of wild mountain ginseng ... Liver Care Honzo Seika Chinese Herbal Aroma Oil
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid ... (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Matched Categories: … combinations of penicillins …
Experimental
Matched Synonyms: … 3'-O-Methylquercetin …
Matched Iupac: … 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … , Noonan syndrome, idiopathic short stature, and adult- or childhood-onset growth hormone deficiency. ... fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults ... of recombinant HGH. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Matched Products: … ZOMACTON Powder and Solvent for Solution for Injection 10mg ... ZOMACTON Powder and Solvent for Solution for Injection 4 mg ... GENOTROPIN® 12MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … [A251610, A251625] However, loperamide is associated with a risk for experiencing a range of adverse ... withdrawal symptoms and to induce euphoria. ... effects, often life-threatening, if taking for non-therapeutic reasons or at doses higher than the recommended …
Matched Mixtures name: … Meds on the Go ... Anti Diarrheal and Anti Gas ... Anti Diarrheal and Anti Gas …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... LOMOTIL ODT ... Care One Anti Diarrheal …
Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Synonyms: … Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis …
Matched Iupac: … )oxy]sulfonyl}oxy)methyl]oxolan-2-yl]oxy}-4,5-bis({[(dihydroxyalumanyl)oxy]sulfonyl}oxy)-2-[({[(dihydroxyalumanyl ... )oxy]sulfonyl}oxy)methyl]oxan-3-yl]oxy}sulfonyl)oxy]alumanediol alumanetriol hydrate ... [({[(2R,3R,4S,5R,6R)-6-{[(2S,3S,4R,5R)-3,4-bis({[(dihydroxyalumanyl)oxy]sulfonyl}oxy)-2,5-bis[({[(dihydroxyalumanyl …
Matched Description: … Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal ... It is sold under many brands and is available in both tablet and suspension forms. ... Sucralfate has been shown to be a well-tolerated and safe drug. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Synonyms: … 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl ... )furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one ... 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside) …
Matched Iupac: … 15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy ... hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one
Matched Description: … Etoposide acts primarily in the G2 and S phases of the cell cycle. ... Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death ... A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin ... 1 and Type 2 Diabetes. ... is a slowly progressing metabolic disorder caused by a combination of genetic and lifestyle factors …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... RapiLog One Insulin Aspart Injection (rDNA Origin) 100U/mL, Pre-filled Pen ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 …
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid ... cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid ... (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Description: … It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, ... and milk. …
Matched Mixtures name: … Swiss One Multivitamin and Mineral Caplet ... Formula O-care Vitamin and Mineral Supplement ... One Daily Vitamin and Mineral Dietary Supplement …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Biona-vit Controls and Prevents Hair Loss …
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
Matched Description: … Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer ... THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal …
Matched Description: … With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine ... DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose …
Experimental
Matched Name: … 1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate …
Displaying drugs 501 - 525 of 702 in total