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Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Products: … BERIPLEX P/N 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Experimental
Matched Name: … 3-phospho-D-glyceric acid …
Matched Iupac: … (2R)-2-hydroxy-3-(phosphonooxy)propanoic acid …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … [L50592] This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide …
Matched Iupac: … N-hydroxy-2-[N-(2-hydroxyethyl)[1,1'-biphenyl]-4-sulfonamido]acetamide …
Dolichovespula arenaria venom protein is an extract of Dolichovespula arenaria venom. Dolichovespula arenaria venom protein is used in allergenic testing.
Approved
Matched Categories: … Bee and Wasp Venom …
Matched Products: … Hymenoptera Venom Products-yellow Hornet Venom Protein (550 Mcg) …
Experimental
Matched Name: … 2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2-(hydroxymethyl)-5-[(2R)-2-hydroxynonyl]oxolan-2-yl ... ]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol …
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Synonyms: … 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole ... (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … EKLIPS FORT 100/25 FILM TABLET, 28 TABLET ... SARVASTAN FORT 100/25 MG FILM TABLET, 28 ADET ... SARILEN PLUS 100 MG/25 MG FILM TABLET, 28 ADET …
Matched Categories: … Angiotensin 2 Receptor Blocker ... losartan and diuretics ... losartan and amlodipine ... Angiotensin II Type 2 Receptor Blockers ... Angiotensin II receptor blockers (ARBs) and diuretics …
Matched Products: … LOSARTAN ATID 25MG ... LOSARTAN ATID 50MG ... LOSARTAN ATID 100MG …
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
Bicyclol is under investigation in clinical trial NCT02944552 (The Multi Center, Randomized, Double-blind, Positive Controlled Study of Bicyclol in the Treatment of Acute DILI).
Investigational
Matched Synonyms: … 4,4'-bi-1,3-benzodioxole)-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester …
Matched Iupac: … methyl 4-[5-(hydroxymethyl)-7-methoxy-2H-1,3-benzodioxol-4-yl]-7-methoxy-2H-1,3-benzodioxole-5-carboxylate …
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration ... L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... ORCIPOL 500 MG/500 MG FILM TABLET, 28 ADET …
Matched Categories: … MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... C-FLOX 250 TABLETS 250 mg …
Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body...
Approved
Matched Synonyms: … calcium bis[()-D-glycero-D-gulo-heptonate] ... calcium bis[()-D-glycero-D-ido-heptonate] ... calcium ()-D-gluco-heptonate …
Matched Description: … Calcium is also needed for the heart, muscles, and nervous system to work properly. …
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Name: … Indole-3-Glycerol Phosphate …
Matched Iupac: … [(2R,3S)-2,3-dihydroxy-3-(1H-indol-3-yl)propoxy]phosphonic acid …
Matched Categories: … Indicators and Reagents …
Disaccharide tripeptide glycerol dipalmitoyl is under investigation in clinical trial NCT00003667 (Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma).
Investigational
Matched Name: … Disaccharide tripeptide glycerol dipalmitoyl …
Matched Iupac: … 3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5,6-dihydroxy-1-oxohexan-3-yl]oxy}propanamido ... (2R)-1-{[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R,3R,4R,5R)-2-acetamido-4-{[(2S,3R,4R,5S,6R)- ... ]propanamido]butanamido]propanoyl]oxy}-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …
Matched Description: … Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma). ... Disaccharide tripeptide glycerol dipalmitoyl is under investigation in clinical trial NCT00003667 (Combination …
Experimental
Matched Name: … Tris-Hydroxymethyl-Methyl-Ammonium …
Matched Iupac: … tris(hydroxymethyl)(methyl)azanium …
Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Water Hyssop Whole ... Coastal Water-hyssop Whole …
Matched Mixtures name: … Ato Standard Intensivecream ... Ato Standard Premium Mildcream …
Matched Products: … GZE Watery Sun Gel ... eves centella 20 V1 Volume Ampoule …
Investigational
Matched Synonyms: … Iap inhibitor at-406 ... PYRROLO(1,2-A)(1,5)DIAZOCINE-8-CARBOXAMIDE, N-(DIPHENYLMETHYL)DECAHYDRO-5-(((2S)-2-(METHYLAMINO)-1-OXOPROPYL ... (5S,8S, 10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo …
Matched Iupac: … (5S,8S,10aR)-N-(diphenylmethyl)-5-[(2S)-2-(methylamino)propanamido]-3-(3-methylbutanoyl)-6-oxo-decahydropyrrolo …
Experimental
Matched Name: … 6-Hydroxymethyl-7,8-Dihydropterin …
Matched Iupac: … 2-amino-6-(hydroxymethyl)-3,4,7,8-tetrahydropteridin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
RH-1 has been used in trials studying the treatment of Advanced Solid Tumors and Non-Hodgkin's Lymphoma.
Experimental
Investigational
Matched Synonyms: … 2,5-Cyclohexadiene-1,4-dione, 2,5-bis(1-aziridinyl)-3-(hydroxymethyl)-6-methyl- …
Matched Iupac: … 2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione …
Matched Description: … RH-1 has been used in trials studying the treatment of Advanced Solid Tumors and Non-Hodgkin's Lymphoma …
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol ... 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine ... 2-chloro-9-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at ... Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … EVOLTU 20 MG/ 20 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE , 1 ADET …
Experimental
Matched Synonyms: … 5-hydroxymethyluridine-2'-deoxy-5'-monophosphate …
Matched Name: … 2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate) …
Matched Iupac: … {[(2R,3S,5R)-3-hydroxy-5-[5-(hydroxymethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2-yl]methoxy …
Experimental
Matched Name: … 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol …
Matched Iupac: … (2R,3R,4S,5R,6R)-2-(hexyloxy)-6-(hydroxymethyl)oxane-3,4,5-triol …
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Iupac: … (1S,9S,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene …
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Salts cas: … 18609-21-7 …
Matched Mixtures name: … Medique at Home Cold Relief ... Medique at Home Decorel Forte ... Well At Walgreens Multi-Symptom Severe Cold Green Tea and Honey Lemon flavors …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …
GPX-150 has been used in trials studying the treatment of Soft Tissue Sarcoma and Advanced Solid Tumors - Phase 1 Population.
Investigational
Matched Synonyms: … hydroxyethyl)-12-imino-1-methoxy-, (8R,10S)- ... -((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-8-(2- …
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … GPX-150 has been used in trials studying the treatment of Soft Tissue Sarcoma and Advanced Solid Tumors …
Matched Salts cas: … 236095-24-2
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Synonyms: … [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid ... [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid ... (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Displaying drugs 526 - 550 of 4591 in total