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Displaying drugs 526 - 550 of 1301 in total
Experimental
Matched Synonyms: … p-nitrophenyl phosphonobutanoyl L-alanine ... N-[4-(4-nitrophenylphospho)butyryl]-L-alanine
Matched Name: … N-[4-(4-nitrophenylphospho)butanoyl]-L-alanine
Experimental
Matched Name: … 2-Hydroxy-Tryptophan
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss ... [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of ... 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia ... PROLIA ... PROLIA® …
Experimental
Matched Name: … Magnesium aspartate hydrochloride
Matched Iupac: … magnesium(2+) (2S)-2-aminobutanedioate hydrochloride
Matched Salts name: … Magnesium aspartate hydrochloride trihydrate …
Investigational
Matched Synonyms: … Tolmetin glycine amide …
Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-glutamine,298-alanine,429-leucine), anti-(human programmed cell death protein …
Matched Description: … Rulonilimab is under investigation in clinical trial NCT05408221 (The Efficacy and Safety of Rulonilimab …
Experimental
Matched Synonyms: … L-threonyl-l-prolyl-l-prolyl-l-threonine
Investigational
Matched Synonyms: … Arginine glutamate ... L-Arginine L-glutamate …
Matched Name: … Arginine glutamate …
Matched Categories: … arginine glutamate ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids, Peptides, and Proteins …
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem]
Approved
Experimental
Matched Name: … D-Serine
Matched Description: … It is synthesized from GLYCINE or THREONINE. ... It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem] …
Experimental
Matched Name: … Methionine Phosphinate …
Investigational
Matched Synonyms: … D-arginine, 4-benzoyl-d-phenylalanyl-d-seryl-d-tryptophyl-d-seryl-2,3,4,5,6-pentafluoro-d-phenylalanyl …
Matched Salts name: … CBP-501 acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intracellular Signaling Peptides and Proteins …
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Salts name: … Diethylpropion hydrochloride
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Diethylpropion Hydrochloride ... Diethylpropion Hydrochloride ER ... Diethylpropion HydrochlorideER ER …
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Description: … , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... [A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate ... Glatiramer acetate exhibits several immunomodulatory effects and reduces the relapse rate of relapsing-remitting …
Matched Salts name: … Glatiramer acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... glatiramer acetate
Matched Products: … Glatiramer Acetate ... Teva-glatiramer Acetate ... Glatiramer Acetate Injection …
Experimental
Matched Synonyms: … S-Arsono-L-cysteine
Nona-arginine is under investigation in clinical trial NCT00264706 (PolyArginine Treated vEiN grafTs (PATENT)).
Investigational
Matched Synonyms: … Nona-L-arginine
Matched Name: … Nona-arginine
Matched Description: … Nona-arginine is under investigation in clinical trial NCT00264706 (PolyArginine Treated vEiN grafTs …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … Cysteamine
Matched Name: … Cysteamine
Matched Description: … [L15606] Cysteamine eye drops are a practical and effective option for those affected by ocular cystinosis ... eyes and kidneys. ... some in capsule form, and others in ophthalmic solution form. …
Matched Salts name: … Cysteamine hydrochloride ... Cysteamine bitartrate …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... Cystine Depleting Agents ... Cystine Disulfide Reduction …
Approved
Matched Synonyms: … Paramethasone acetate ... Paramethasone 21-acetate
Matched Name: … Paramethasone acetate
Matched Iupac: … 11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
Experimental
Matched Synonyms: … Hydrochloric acid …
Matched Name: … Hydrochloric acid …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... hydrochloric acid ... hydrochloric acid …
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Glycine betaine ... 2-(Trimethylammonio)Acetate ... 2-N,N,N-trimethylammonio acetate
Matched Iupac: … 2-(trimethylazaniumyl)acetate
Matched Description: … occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and ... levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and
Matched Mixtures name: … Betaine HCl and Pepsin ... Rocky Mountain Multiple Vit and Min Mega Tab ... Glutamic Acid Pepsin and Betaine Tablets …
Matched Salts name: … Betaine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... betaine hydrochloride
Experimental
Matched Synonyms: … N-acetyl-L-cysteine zinc salt …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cysteine
Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.
Investigational
Matched Synonyms: … 3-203-FIBROLASE (3-SERINE) (AGKISTRODON CONTORTRIX CONTORTRIX RECOMBINANT) …
Matched Categories: … Enzymes and Coenzymes …
D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva . These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity .
Experimental
Matched Synonyms: … D-Prolin
Matched Name: … D-Proline
Matched Description: … D-amino acids have been found in relatively high abundance in human plasma and saliva [A19262]. ... D-proline is an isomer of the naturally occurring amino acid, L-Proline. …
Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in...
Approved
Matched Description: … Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. ... It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular ... It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. …
Matched Salts name: … Meclizine hydrochloride
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Meclizine Hydrochloride ... Meclizine Hydrocloride ... Meclizine hydrochloride
Experimental
Matched Name: … gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Approved
Investigational
Vet approved
Matched Synonyms: … Megestrol acetate ... 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate ... 17α-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate
Matched Name: … Megestrol acetate
Matched Iupac: … ,11S,14R,15S)-14-acetyl-2,8,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-6,8-dien-14-yl acetate
Matched Description: … As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor ... A progestational hormone used most commonly as the acetate ester. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Combination Contraceptives (with Estrogen and derivatives) ... megestrol and estrogen ... megestrol and estrogen …
Matched Products: … Megestrol Acetate ... Megestrol acetate ... MEGESTROL ACETATE
Displaying drugs 526 - 550 of 1301 in total