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Displaying drugs 551 - 575 of 1116 in total

10-formyl-5,8,10-trideazafolic acid

Experimental
Matched Name: … 10-formyl-5,8,10-trideazafolic acid …

Succinylcholine

Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. Its...
Approved
Matched Description: … Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and ... a means of neuromuscular blockade during intubation and surgical procedures. ... [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as …
Matched Products: … LYSTHENON FORTE %2 ENJEKSİYONLUK ÇÖZELTİ, 25 AMPUL ... Pharmaniaga Suxamethonium Chloride 100mg/2ml Solution for Injection ... MARTINDALE PHARMA SUXAMETHONIUM CHLORIDE SOLUTION FOR INJECTION 50MG/ML …

IFx-Hu2.0

IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic …

Benzydamine

Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system. Although the indazole analogue benzydamine is a...
Approved
Matched Description: … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal ... hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and ... benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has various physicochemical properties and …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour ... FARHEX FORTE SPREY …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiinflammatory and Antirheumatic Products ... Genito Urinary System and Sex Hormones …
Matched Products: … Tantum Verde forte - Mundspray ... BENZIRIN® FORTE 0.3% SOLUCIÓN BUCAL ... Difflam Forte Anti-Inflammatory Throat Spray …

RU82197

Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid …

Cisatracurium

Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly ... [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times ... non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form …
Matched Products: … Nimbex Forte Injection 150 mg/30 ml ... Cisatracurium-hameln 2 mg/ml solution for injection/infusion ... Cisatracurium Kabi 2 mg/ml solution for injection or infusion …

AVR-RD-05

AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the …
Matched Description: … It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII) …

Lipoic acid

A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Thioctic acid D-form …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …

Cloxacillin

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … DRY FORTE ... MEIXAM POWDER FOR SOLUTION FOR INJECTION 500MG/VIAL ... CLOXACILLIN STRAGEN POWDER FOR SOLUTION FOR INJECTION 500 MG/VIAL …

Glucosamine

Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... as a medical therapy varies due to contradictory and findings with unclear clinical significance during …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... CARTICAP FOR …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROSULF FORTE ... Donna Forte Capsule 500mg ... CUINE POWDER FOR ORAL SOLUTION …

Diclofenac

Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins ... PGs contribute to inflammation and pain signalling. …
Matched Mixtures name: … Dfs 1.5%/ms 25%/menth 6%/cap 0.025% Pak ... DFS 75mg DR/MS 25%/MENTH 6%/CAP 0.025% PAK ... ARIFLAM FORTE …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever ... VALTO FORTE ... VOLVIL® FORTE …

ABSK-012

Investigational
Matched Synonyms: … 3-(5-cyano-4-(cyclopropylamino)pyridin-2-yl)-1-(6-formyl-5-((4-methyl-2-oxopiperazin-1-yl)methyl)pyridin ... N′-[5-Cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl]-2- ... Urea, N′-[5-cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl …
Matched Iupac: … 3-[5-cyano-4-(cyclopropylamino)pyridin-2-yl]-1-{6-formyl-5-[(4-methyl-2-oxopiperazin-1-yl)methyl]pyridin …

Viper antivenom

Viper antivenom consists of antibodies derived from horses immunized and subsequently developed antibodies against snake venoms. ANAVIP, an equine-derived antivenom made with venom from Bothrops asper and Crotalus durissus, was first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation.
Approved
Matched Synonyms: … Antivenin (bothrops atrox/crotalus adamanteus/crotalus atrox/crotalus durissus terrificus) (equine) …
Matched Description: … Viper antivenom consists of antibodies derived from horses immunized and subsequently developed antibodies ... ANAVIP, an equine-derived antivenom made with venom from _Bothrops asper_ and _Crotalus durissus_, was ... first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment ... [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Antidote for Acetaminophen Overdose …
Matched Products: … SIRAN FORTE ... ANCARE SOLUTION FOR IV INFUSION 100MG/ML ... HIDONAC SOLUTION FOR INFUSION 5 g/25 ml …

Cefadroxil

Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VOCEFA FORTE ... CEFFORD FORTE ... OPICEF FORTE …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Description: … this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication ... first approved for use in the United States in 2001. ... [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Adrenergics for Systemic Use ... Drugs for Obstructive Airway Diseases ... formoterol and mometasone ... formoterol and budesonide ... formoterol and fluticasone …
Matched Products: … FORMO-ARISTO 12UG ... Foradil Dry Powder Capsules for Inhalation ... FORADIL CAPSULE FOR INHALATION 12 mcg/capsule …

Codeine

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Description: … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for ... agent, and is also recommended in certain diseases with incessant coughing. ... Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease …
Matched Mixtures name: … Triatec-8 Fort ... Acetazone Forte C8 ... COUGHLAX FORTE SYRUP …
Matched Categories: … Cough and Cold Preparations ... codeine and ibuprofen ... codeine and paracetamol ... Opium Alkaloids and Derivatives ... codeine and acetylsalicylic acid …
Matched Products: … TRYASOL CODEIN FORTE ... CODEINUM PHOS FORT COMPR50 …

Levoleucovorin

Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … (6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid ... N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Description: … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... reduction and act as a cellular replacement for the co-factor THF, thereby preventing these toxic side ... and methionine before incorporation into DNA or protein. …
Matched Mixtures name: … Biopar delta-FORTE …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... Detoxifying Agents for Antineoplastic Treatment …

Trastuzumab

Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... cancer, it is the second biosimilar approved in the U.S. for the treatment of cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … HERZUMA® 440MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION ... Herzuma (trastuzumab) 150 mg Powder for Concentrate for Solution for Infusion ... HERZUMA® 150MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …

Polyvinyl alcohol

Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
Approved
Matched Description: … It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing …
Matched Mixtures name: … Murine Tears for Dry Eyes ... Murine Plus for Dry Eyes Redness Relief …
Matched Products: … Liquifilm Forte 3% ... Artificial Tears for Dry Eyes …

Trastuzumab emtansine

Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent, DM1. T-DM1 combines two strategies-- anti-HER2 activity and targeted intracellular delivery of the potent anti-microtubule agent, DM1 (a maytansine derivative)--to produce cell cycle arrest and apoptosis....
Approved
Investigational
Matched Description: … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive ... , metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic disease ... First that trastuzumab emtansine and trastuzumab cannot be interchanged. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KADCYLA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL ... KADCYLA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 160MG/VIAL ... Kadcyla 160 mg powder for concentrate for solution for infusion …

Siltuximab

Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment...
Approved
Investigational
Matched Description: … Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high ... who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. ... MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Sylvant 400mg Powder for Concentrate for Solution for Infusion ... Sylvant 100mg Powder for Concentrate for Solution for Infusion ... SYLVANT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL …

Streptomycin

Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside …
Matched Iupac: … [(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl …
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Drugs for Treatment of Tuberculosis …
Matched Products: … Streptomycin for Injection USP ... STREPTOMYCIN SULFATE FOR INJECTION 1 g/vial …

Cresol

Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … concentrations normally found in the environment however, cresols do not pose any significant risk for ... pain, and/or vomiting. ... Ingestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal …
Matched Mixtures name: … Root Canal Therapy …
Matched Products: … Formo Cresol ... Buckleys Formo Cresol …

Polatuzumab vedotin

Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Matched Description: … [L6658] Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was ... human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl ... drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 140MG ... POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 30MG ... POLIVY 140mg Powder For Concentrate For Solution For Infusion …
Displaying drugs 551 - 575 of 1116 in total