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Displaying drugs 551 - 575 of 3158 in total

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved

Zafirlukast

Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Categories: … Anti-Asthmatic Agents …

Trazodone

Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Categories: … Anti-Anxiety Agents …

Azelastine

Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Categories: … Anti-Allergic Agents …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Categories: … Anti-Anxiety Agents …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Categories: … Anti-Ulcer Agents …

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Categories: … Anti-Infective Agents …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Categories: … Anti-Infective Agents …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Name: … Anti-inhibitor coagulant complex …
Matched Description: … Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains …

Natalizumab

Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … Anti-VLA4 ... Anti-alpha4 integrin ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE …

Idecabtagene vicleucel

Multiple myeloma is a cancer where plasma cells rapidly divide out of control. These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed on non-cancerous cells. Multiple myeloma is typically treated with an immunomodulatory agent like lenalidomide, a proteasome inhibitor like bortezomib, or an anti-CD38 monoclonal...
Approved
Matched Synonyms: … Anti-BCMA CAR T cell …
Matched Description: … [A232558] The chimeric antigen receptor of idecabtagene vicleucel includes an anti-B-cell maturation ... immunomodulatory agent like [lenalidomide],[A232593] a proteasome inhibitor like [bortezomib], or an anti-CD38 …

Tarlatamab

Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …

Axicabtagene ciloleucel

Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Matched Synonyms: … Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen …
Matched Description: … Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. ... [A216163] Once T-cells are collected from the patient, they are genetically engineered to express anti-CD19 ... of researchers at the National Cancer Institute (NCI), who demonstrated that T cells expressing an anti-CD19 …

Spesolimab

Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain) …

Pucotenlimab

Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus …
Matched Description: … Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly …
Matched Mixtures name: … Terrasil Rapid-Clear Anti-Fungal ... Terrasil Rapid-Clear Anti-Fungal ... Canesten Combi 1 Day Internal + External Creams …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local …
Matched Products: … Anti-Fungal ... Anti Fungal ... Aspiera Anti-Fungal …

Bemiparin

Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and …
Matched Products: … Ivor 2500 IE Anti-Xa/0,2 ml Injektionslösung in Fertigspritzen ... Ivor 3500 IE Anti-Xa/0,2 ml Injektionslösung in Fertigspritzen ... Ivorat 25.000 IE Anti-Xa/ml - Injektionslösung in Fertigspritzen …

Octasulfur

Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Mixtures name: … Sebex Antidandruff, anti-seborrheic dermatitis, anti-psoriasis ... Glovers Anti-Dandruff ... Anti-acne Formula-light …
Matched Products: … Spai-sons Acid Anti-dandruff ... Joesoef Skincare Anti Acne ... ClearCalm 3 Anti-Acne Starter …

Undecylenic acid

Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Products: … Flexitol Anti Fungal ... Anti-Fungal Pen CVS ... Natralia Anti Fungal …

Aluminum zirconium pentachlorohydrate

Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Products: … Skin So Soft Original Anti-Perspirant Deodorant ... Skin So Soft Soft and Sensual Anti-Perspirant Deodorant ... Skin So Soft Signature Silk Anti-Perspirant Deodorant …

Tolnaftate

Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Description: … Tolnaftate is a synthetic over-the-counter anti-fungal agent. …
Matched Categories: … Anti-Infective Agents …
Matched Products: … Anti-Fungal ... HC Max Anti-Fungal ... HC Max Anti Fungal …

Tetanus immune globulin, human

Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.
Approved
Matched Products: … SERUM ANTI TETANUS (KUDA) 1.500 IU ... SERUM ANTI TETANUS (KUDA) 20.000 IU ... IGANTET ANTI-TETANUS IMMUNOGLOBULIN GRIFOLS INJECTION 250 IU/ml …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. …
Matched Mixtures name: … Anti-bacterial 3pk ... Anti-bacterial 3pk ... Anti-bacterial 3pk …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local ... Miscellaneous Local Anti-infectives …
Matched Products: … Clean Revolution Anti-Bacterial Hand Refill Supply Container - Anti-Bacterial - ELIMINATES 99.9% Germs ... Clean Revolution Anti-Bacterial Foaming Hand Refill Supply Container - Anti-Bacterial - ELIMINATES 99.9% ... Candy Apple Anti Bacterial Hand Sanitizer …

Peppermint oil

Extracted from the stem, leaves, and flowers of Mentha piperita L. plant, peppermint oil (Mentha piperita) is a popular essential oil used in aromatherapy for both external and internal use. Mentha piperita is a hybrid of spearmint (Mentha spicata) and water mint (Mentha aquatica) . Medicinal use of herbal ingredients...
Approved
Investigational
Matched Description: … oil is used as a flavouring agent in foods and fragrance in hygienic or cosmetic products, and as an anti-itch …
Matched Products: … Anti Itch Balm ... Anti-Bacterial Sticker …
Displaying drugs 551 - 575 of 3158 in total