Displaying drugs 551 - 575 of 3154 in total
Safinamide
Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Approved
Investigational
Matched Categories: … Anti-Parkinson Drugs …
Remdesivir
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia and acute respiratory distress syndrome (ARDS); COVID-19 can be fatal. Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase...
Approved
Investigational
Matched Categories: … Anti-Infective Agents …
Raloxifene
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic …
Relugolix
Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions. It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids, and more recently by the United States' FDA in 2020, under the brand name...
Approved
Investigational
Matched Categories: … Anti-Gonadotropin-Releasing Hormones …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Categories: … Anti-Anxiety Agents …
Haloperidol
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Categories: … Anti-Dyskinesia Agents …
Simeprevir
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Categories: … Anti-Infective Agents …
Cholecalciferol
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Progesterone
Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Zafirlukast
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Categories: … Anti-Asthmatic Agents …
Trazodone
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Categories: … Anti-Anxiety Agents …
Azelastine
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Categories: … Anti-Allergic Agents …
Fluvoxamine
Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.
Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Categories: … Anti-Anxiety Agents …
Cimetidine
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Categories: … Anti-Ulcer Agents …
Ketoconazole
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Categories: … Anti-Infective Agents …
Quinidine
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Categories: … Anti-Infective Agents …
Musa acuminata fruit
Musa acuminata fruit allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Dwarf banana fruit ... Musa nana fruit ... Musa acuminata fruit …
Matched Name: … Musa acuminata fruit …
Matched Description: … Musa acuminata fruit allergenic extract is used in allergenic testing. …
Matched Name: … Musa acuminata fruit …
Matched Description: … Musa acuminata fruit allergenic extract is used in allergenic testing. …
Saw palmetto
Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Sabal Palm Fruit ... Brahea Serrulata Fruit ... Corypha Repens Fruit …
Myristica fragrans fruit
Myristica fragrans fruit allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Mace fruit ... Nutmeg fruit ... Myristica aromatica fruit …
Matched Name: … Myristica fragrans fruit …
Matched Description: … Myristica fragrans fruit allergenic extract is used in allergenic testing. …
Matched Name: … Myristica fragrans fruit …
Matched Description: … Myristica fragrans fruit allergenic extract is used in allergenic testing. …
Bilberry
Approved
Experimental
Matched Synonyms: … Bilberry fruit ... Dwarf bilberry fruit ... European blueberry fruit …
Muromonab
Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).
Approved
Investigational
Matched Synonyms: … Anti-CD3 …
Human Rho(D) immune globulin
Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the...
Approved
Investigational
Matched Synonyms: … Anti-D immunoglobulin ... Anti-D immunoglobulins ... Human anti-D immunoglobulin …
Matched Categories: … anti-D (rh) immunoglobulin …
Matched Products: … ANTİ-D İMMÜNGLOBULİN GRİFOLS 1500 IU (300 MCG)/2 ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR …
Matched Categories: … anti-D (rh) immunoglobulin …
Matched Products: … ANTİ-D İMMÜNGLOBULİN GRİFOLS 1500 IU (300 MCG)/2 ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR …
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Synonyms: … Anti-PD-1 monoclonal antibody MGA012 …
Naxitamab
Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and within...
Approved
Matched Synonyms: … Anti-Gd2 monoclonal antibody 3F8 humanized ... Humanized anti-Gd2 monoclonal antibody 3F8 ... Anti-Gd2 igg3 monoclonal antibody 3F8 humanized …
Matched Description: … [A224604] The first anti-GD2-monoclonal IgG antibody to be approved by the FDA for the treatment of ... with GM-CSF, a factor known to enhance the granulocyte-mediated antibody-dependent cytotoxicity of anti-GD2 …
Matched Description: … [A224604] The first anti-GD2-monoclonal IgG antibody to be approved by the FDA for the treatment of ... with GM-CSF, a factor known to enhance the granulocyte-mediated antibody-dependent cytotoxicity of anti-GD2 …
Glofitamab
Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488]
Glofitamab was approved...
Approved
Investigational
Matched Synonyms: … Anti-CD20/CD3 bispecific monoclonal antibody RO7082859 …
Displaying drugs 551 - 575 of 3154 in total