Displaying drugs 576 - 600 of 10462 in total
Plazomicin
Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically derived from DB12604. The structure of plazomicin was established via appending hydroxylaminobutyric acid to DB12604 at position 1 and 2-hydroxyethyl group at position 6' . It was designed to evade all clinically relevant aminoglycoside-modifying enzymes, which contribute to the main...
Approved
Investigational
Matched Iupac: … -2H-pyran-2-yl]oxy}-2-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-3-hydroxycyclohexyl ... (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro ... ]-2-hydroxybutanamide …
Matched Description: … of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position 1 and 2- …
Matched Categories: … MATE 2 Inhibitors …
Matched Description: … of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position 1 and 2- …
Matched Categories: … MATE 2 Inhibitors …
Fosaprepitant
Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Iupac: … (3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl ... }-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid …
Dimethicone
Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Mixtures name: … Pediadermics Eczema 3 …
Matched Products: … Kendall 2-in-1 Cleanser ... Snail Therapy 70 Essence ... Snail Therapy 70 Special Set …
Matched Products: … Kendall 2-in-1 Cleanser ... Snail Therapy 70 Essence ... Snail Therapy 70 Special Set …
Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)
Approved
Investigational
Matched Mixtures name: … 3 ANTIGEN ... ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 5 ADET ... FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and BORDETELLA PERTUSSIS FIMBRIAE 2/ …
Pitolisant
Pitolisant is a selective antagonist or inverse agonist of the histamine H3 receptor used to treat type 1 or 2 narcolepsy. Narcolepsy is a chronic neurological disorder that affects 1 in 2,000 individuals and is characterized by excessive daytime sleepiness, abnormal REM sleep manifestations, sleep paralysis and hypnagogic hallucinations. About...
Approved
Investigational
Matched Iupac: … 1-{3-[3-(4-chlorophenyl)propoxy]propyl}piperidine …
Matched Description: … Pitolisant is a selective antagonist or inverse agonist of the histamine H3 receptor used to treat type 1 or 2 ... [A32025] About 60-70% of patients with narcolepsy experience cataplexy, which is a sudden loss of muscle …
Matched Salts cas: … 903576-44-3 …
Matched Categories: … Histamine-3 Receptor Antagonist/Inverse Agonist ... Histamine-3 (H3) Receptor Antagonists/Inverse Agonists …
Matched Description: … Pitolisant is a selective antagonist or inverse agonist of the histamine H3 receptor used to treat type 1 or 2 ... [A32025] About 60-70% of patients with narcolepsy experience cataplexy, which is a sudden loss of muscle …
Matched Salts cas: … 903576-44-3 …
Matched Categories: … Histamine-3 Receptor Antagonist/Inverse Agonist ... Histamine-3 (H3) Receptor Antagonists/Inverse Agonists …
Dichloroacetic acid
Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase. Early reports of its activity...
Approved
Investigational
Matched Description: … A phase 1 study in 5 patients concluded that DCA was safe, but wasn't designed to establish effectiveness …
Ensulizole
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid …
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that …
Matched Mixtures name: … Shiseido Urban Environment Tinted Uv Protector 3 ... Hawaiian Tropic Herbal Tanning Mist 2 SPF ... Cc Super Active Complete Correction Sunscreen Broad Spectrum SPF 50 70 Beige …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Sungirl SPF 3 ... Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that …
Matched Mixtures name: … Shiseido Urban Environment Tinted Uv Protector 3 ... Hawaiian Tropic Herbal Tanning Mist 2 SPF ... Cc Super Active Complete Correction Sunscreen Broad Spectrum SPF 50 70 Beige …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Sungirl SPF 3 ... Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Edetic acid
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate …
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid …
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid …
Colloidal oatmeal
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Mixtures name: … Pediadermics Eczema 3 ... 5% Oat Facial Cleanser …
Matched Products: … 3-In-1 Relief CVS ... ZO MEDICAL 3-STEP PEEL Kit ... Eczema Care Moisturizing 3 oz. …
Matched Products: … 3-In-1 Relief CVS ... ZO MEDICAL 3-STEP PEEL Kit ... Eczema Care Moisturizing 3 oz. …
Ceftobiprole
Ceftobiprole is a fifth-generation semisynthetic cephalosporin antibacterial which is available commercially as the prodrug ceftobiprole medocaril. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA).
The EMA's Committee for Medicinal Products for Human Use (CHMP)...
Approved
Investigational
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(N-hydroxyimino)acetamido]-8-oxo-3-{[(3E,3'R)-2-oxo ... -[1,3'-bipyrrolidin]-3-ylidene]methyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate ... 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester ... 2-chloroprocaine …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate …
Matched Products: … Nesacaine Ce 2% Inj 20mg/ml ... Nesacaine Ce 3% Inj 30mg/ml …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate …
Matched Products: … Nesacaine Ce 2% Inj 20mg/ml ... Nesacaine Ce 3% Inj 30mg/ml …
Lanthanum carbonate
Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to...
Approved
Matched Synonyms: … Lanthanum(3+) carbonate …
Matched Iupac: … dilanthanum(3+) ion tricarbonate …
Matched Salts cas: … 54451-24-0 …
Matched Iupac: … dilanthanum(3+) ion tricarbonate …
Matched Salts cas: … 54451-24-0 …
Ethylhexyl methoxycrylene
Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states . It returns UV filters to their ground states without absorbing sunlight . It is used as a solvent for crystalline UV filters and is easily emulsified and suitable...
Approved
Experimental
Matched Iupac: … 2-ethylhexyl 2-cyano-3-(4-methoxyphenyl)-3-phenylprop-2-enoate …
Relebactam
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Estradiol valerate
Estradiol Valerate (also known as E2V) is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore...
Approved
Investigational
Vet approved
Matched Description: … produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2- ... primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 …
Matched Mixtures name: … DIVICONT TABLETAS 1 MG/5 MG ... MESIGYNA 5 MG+50 MG/1 ML ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTÖR ... DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET …
Matched Products: … โปรกีโนวา 2 มก. ... PROGYNOVA ® 2 MG ... PROGYNOVA TABLET 2 mg …
Matched Mixtures name: … DIVICONT TABLETAS 1 MG/5 MG ... MESIGYNA 5 MG+50 MG/1 ML ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTÖR ... DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET …
Matched Products: … โปรกีโนวา 2 มก. ... PROGYNOVA ® 2 MG ... PROGYNOVA TABLET 2 mg …
Hydroxypropyl cellulose
Hydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears. It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions,...
Approved
Matched Synonyms: … Cellulose, 2-hydroxypropyl ether …
Influenza B virus B/Massachusetts/2/2012 BX-51B hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Massachusetts/2/2012 BX-51B hemagglutinin antigen (formaldehyde inactivated) …
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Daridorexant
Daridorexant, formerly known as nemorexant, is a selective dual orexin receptor antagonist used to treat insomnia. Insomnia is characterized by difficulties with sleep onset and/or sleep maintenance and impairment of daytime functioning. It chronically affects the person's daily functioning and long-term health effects, as insomnia is often associated with comorbidities...
Approved
Matched Iupac: … 5-chloro-2-[(2S)-1-[5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoyl]-2-methylpyrrolidin-2-yl]-4-methyl-1H- …
Matched Description: … [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin …
Matched Salts cas: … 1792993-84-0 …
Matched Description: … [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin …
Matched Salts cas: … 1792993-84-0 …
Terconazole
Terconazole is an anti-fungal drug that is mainly used to treat vaginal yeast infections (or vaginal candidiasis). It is classified as a triazole ketal derivative. Terconazole was initially approved by the FDA in 1987.[FDA label] This drug is available in cream and suppository forms and both have demonstrated high levels...
Approved
Matched Iupac: … )-4-(propan-2-yl)piperazine ... 1-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl …
Matched Description: … [A178093]Due to the existence of 2 stereocentres, there are 4 possible stereoisomers for terconazole. …
Matched Mixtures name: … TEREX-3 ... Terazol 3 Dual Pak ... Terazol 3 Dual Pak …
Matched Products: … Terazol 3 ... Terazol 3 Vaginal Cream 0.8% ... Terazol 3 Vaginal Ovules 80mg …
Matched Description: … [A178093]Due to the existence of 2 stereocentres, there are 4 possible stereoisomers for terconazole. …
Matched Mixtures name: … TEREX-3 ... Terazol 3 Dual Pak ... Terazol 3 Dual Pak …
Matched Products: … Terazol 3 ... Terazol 3 Vaginal Cream 0.8% ... Terazol 3 Vaginal Ovules 80mg …
Etacrynic acid
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid …
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid …
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3- ... such as counseling patients to keep warm and the use of red blood cell transfusions, approximately 70% …
Drospirenone
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Synonyms: … 6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone …
Matched Iupac: … .0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione ... (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19} …
Matched Mixtures name: … Angeliq 1 mg/2 mg Filmtabletten ... ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADET ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET …
Matched Iupac: … .0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione ... (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19} …
Matched Mixtures name: … Angeliq 1 mg/2 mg Filmtabletten ... ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADET ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET …
SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)
Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Synonyms: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer – B.1.351 …
Matched Name: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351 …
Matched Description: … Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein ... is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 …
Matched Name: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351 …
Matched Description: … Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein ... is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 …
Barium sulfate
Barium sulfate is an inorganic compound with the chemical formula BaSO4 .
Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield .
This drug is used as a contrast agent in...
Approved
Matched Iupac: … barium(2+) sulfate …
Matched Products: … Tomo Cat Barium Sulfate Susp 5% ... Readi-Cat 2 ... MICROBAR CAT-2 …
Matched Products: … Tomo Cat Barium Sulfate Susp 5% ... Readi-Cat 2 ... MICROBAR CAT-2 …
Rufinamide
Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Approved
Displaying drugs 576 - 600 of 10462 in total