Displaying drugs 576 - 600 of 1217 in total
LuLym-T
LuLym-T is an investigational autologous immune cell therapy consisting of activated T Lymphocytes. Developed by Lukas Biomedical, Inc., it is currently being investigated in hepatocellular carcinoma.
Investigational
Matched Synonyms: … Autologous Activated T Lymphocytes (ATL) …
Matched Description: … LuLym-T is an investigational autologous immune cell therapy consisting of activated T Lymphocytes. …
Matched Description: … LuLym-T is an investigational autologous immune cell therapy consisting of activated T Lymphocytes. …
Nitrogen trichloride
Experimental
Matched Synonyms: … Nitrogen chloride …
Matched Categories: … Chlorine Compounds …
Matched Categories: … Chlorine Compounds …
Azathioprine
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and ... A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and …
Matched Salts name: … Azathioprine sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Azathioprine Sodium ... Azathioprine Sodium for Injection …
Matched Salts name: … Azathioprine sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Azathioprine Sodium ... Azathioprine Sodium for Injection …
Hyaluronic acid
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Iupac: … (2S,3S,4R,5R,6R)-3-{[(2S,3R,5S,6R)-4-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3-acetamido …
Matched Description: … oral, topical, and injectable forms. ... Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and ... Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “ …
Matched Mixtures name: … Hyaluronic Acid 60mg and Lidocaine 2% PF ... ELDEEN AGE TWENTY ONE MifitPatch and Serum ... ELDEEN AGE TWENTY ONE MifitPatch and Serum …
Matched Salts name: … Hyaluronate sodium ... Sodium hyaluronate …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Products: … LUBRAVISC (1% SODIUM HYALURONATE) ... MICRODROPS (0.2% SODIUM HYALURONATE) ... DERMAVISC DF (0.6% SODIUM HYALURONATE) …
Matched Description: … oral, topical, and injectable forms. ... Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and ... Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “ …
Matched Mixtures name: … Hyaluronic Acid 60mg and Lidocaine 2% PF ... ELDEEN AGE TWENTY ONE MifitPatch and Serum ... ELDEEN AGE TWENTY ONE MifitPatch and Serum …
Matched Salts name: … Hyaluronate sodium ... Sodium hyaluronate …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Products: … LUBRAVISC (1% SODIUM HYALURONATE) ... MICRODROPS (0.2% SODIUM HYALURONATE) ... DERMAVISC DF (0.6% SODIUM HYALURONATE) …
Methylmethionine chloride
Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also called "Vitamin U", but it is not a true vitamin.
Experimental
Matched Synonyms: … Methiosulfonium chloride …
Matched Name: … Methylmethionine chloride …
Matched Iupac: … [(3S)-3-amino-3-carboxypropyl]dimethylsulfanium chloride …
Matched Description: … Methylmethionine chloride may be useful in helping the healing of gastric ulcers. …
Matched Categories: … Alimentary Tract and Metabolism ... methiosulfonium chloride ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Name: … Methylmethionine chloride …
Matched Iupac: … [(3S)-3-amino-3-carboxypropyl]dimethylsulfanium chloride …
Matched Description: … Methylmethionine chloride may be useful in helping the healing of gastric ulcers. …
Matched Categories: … Alimentary Tract and Metabolism ... methiosulfonium chloride ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Acriflavine
Experimental
Matched Synonyms: … Acriflavinium chloride …
Matched Iupac: … 3,6-diamino-10-methylacridin-10-ium acridine-3,6-diamine chloride …
Matched Categories: … Indicators and Reagents ... acriflavinium chloride …
Matched Iupac: … 3,6-diamino-10-methylacridin-10-ium acridine-3,6-diamine chloride …
Matched Categories: … Indicators and Reagents ... acriflavinium chloride …
Butyl chloride
Vet approved
Matched Synonyms: … n-Butyl chloride ... n-Propylcarbinyl chloride …
Matched Name: … Butyl chloride …
Matched Name: … Butyl chloride …
Magnesium chloride
Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Approved
Matched Synonyms: … Anhydrous magnesium chloride ... Magnesium chloride anhydrous …
Matched Name: … Magnesium chloride …
Matched Description: … Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can …
Matched Mixtures name: … Magnesium Chloride ... Plasma-Lyte 148 and dextrose ... Aminosyn II and Dextrose …
Matched Salts name: … Magnesium chloride hydrate ... Magnesium chloride hexahydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Chlorides ... Chlorine Compounds …
Matched Products: … Magnesium Chloride ... Magnesium Chloride 606.5mg ... MAGNESIUM CHLORIDE Dietary Supplement …
Matched Name: … Magnesium chloride …
Matched Description: … Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can …
Matched Mixtures name: … Magnesium Chloride ... Plasma-Lyte 148 and dextrose ... Aminosyn II and Dextrose …
Matched Salts name: … Magnesium chloride hydrate ... Magnesium chloride hexahydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Chlorides ... Chlorine Compounds …
Matched Products: … Magnesium Chloride ... Magnesium Chloride 606.5mg ... MAGNESIUM CHLORIDE Dietary Supplement …
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and …
Matched Salts name: … Montelukast sodium …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Montelukast Sodium ... Montelukast sodium ... MONTELUKAST SODIUM …
Matched Salts name: … Montelukast sodium …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Montelukast Sodium ... Montelukast sodium ... MONTELUKAST SODIUM …
Thallous chloride
Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation of thallium from its ores. It is created from the treatment of thallium(I) sulfate with hydrochloric acid. This solid crystallizes in the caesium chloride motif. It is used as a diagnostic radiopharmaceutical. It is used...
Approved
Matched Synonyms: … Thallium chloride ... Thallium(I) chloride …
Matched Name: … Thallous chloride …
Matched Description: … It is used for diagnosis of heart and parathyroid problems. ... pain or discomfort, chills, confusion, cough, difficulty with breathing, difficulty with swallowing, and ... Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation …
Matched Products: … THALLOUS CHLORIDE (Tl201) INJECTION 37 MBq/ml …
Matched Name: … Thallous chloride …
Matched Description: … It is used for diagnosis of heart and parathyroid problems. ... pain or discomfort, chills, confusion, cough, difficulty with breathing, difficulty with swallowing, and ... Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation …
Matched Products: … THALLOUS CHLORIDE (Tl201) INJECTION 37 MBq/ml …
Tranexamic acid
Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883]
It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Tranexamic Acid In Sodium Chloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Tranexamic Acid In Sodium Chloride …
Technetium Tc-99m pertechnetate
Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … It also concentrates in the thyroid gland, salivary glands, gastric mucosa, and choroid plexus. ... following tissues: thyroid, salivary gland, urinary bladder (for detection of vesico-ureteral reflux), and ... technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted and …
Matched Mixtures name: … GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ …
Matched Salts name: … Technetium Tc-99m sodium pertechnetate …
Matched Categories: … Indicators and Reagents …
Matched Products: … Sodium Pertechnetate 99mtc Injection …
Matched Mixtures name: … GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ …
Matched Salts name: … Technetium Tc-99m sodium pertechnetate …
Matched Categories: … Indicators and Reagents …
Matched Products: … Sodium Pertechnetate 99mtc Injection …
Mercuric amidochloride
Experimental
Matched Synonyms: … Mercuric chloride, ammoniated …
Matched Iupac: … mercury(2+) ion azanide chloride …
Matched Categories: … Antiseptics and Disinfectants ... Chlorides ... Chlorine Compounds …
Matched Iupac: … mercury(2+) ion azanide chloride …
Matched Categories: … Antiseptics and Disinfectants ... Chlorides ... Chlorine Compounds …
Somatrogon
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES ... HUMAN GROWTH HORMONE-CARBOXY-TERMINAL PEPTIDE (CTP) OF THE BETA CHAIN OF HUMAN CHORIONIC GONADOTROPIN …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... It is a chimeric product generated by fusing three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... It is a chimeric product generated by fusing three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Stannous chloride
Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis...
Approved
Matched Synonyms: … Stannous chloride anhydrous ... Stannous chloride,anhydrous …
Matched Name: … Stannous chloride …
Matched Description: … These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) ... Stannous chloride is used as a source of tin in radiopharmaceutical kits. …
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Spectrum Performa Multivitamins and Minerals Tablets …
Matched Salts name: … Stannous chloride dihydrate …
Matched Name: … Stannous chloride …
Matched Description: … These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) ... Stannous chloride is used as a source of tin in radiopharmaceutical kits. …
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Spectrum Performa Multivitamins and Minerals Tablets …
Matched Salts name: … Stannous chloride dihydrate …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … t-plasminogen activator ... Tissue plasminogen activator ... Tissue plasminogen activator alteplase …
Matched Description: … [tenecteplase] and [reteplase], have also been developed. ... alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and …
Matched Mixtures name: … Activase RT-PA ... Activase RT-PA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Tissue Plasminogen Activator ... Tissue Plasminogen Activator, antagonists & inhibitors …
Matched Products: … Activase ... Cathflo Activase ... Activase RT-PA Inj …
Matched Description: … [tenecteplase] and [reteplase], have also been developed. ... alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and …
Matched Mixtures name: … Activase RT-PA ... Activase RT-PA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Tissue Plasminogen Activator ... Tissue Plasminogen Activator, antagonists & inhibitors …
Matched Products: … Activase ... Cathflo Activase ... Activase RT-PA Inj …
Boric acid
Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes . It...
Approved
Matched Synonyms: … hydrogen borate …
Matched Description: … Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive ... in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes ... It is known to exhibit some antibacterial activity against infections such as bacterial vaginosis and …
Matched Products: … ACQUA BORICA CARLO ERBA …
Matched Description: … Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive ... in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes ... It is known to exhibit some antibacterial activity against infections such as bacterial vaginosis and …
Matched Products: … ACQUA BORICA CARLO ERBA …
Citicoline
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Approved
Experimental
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM …
Carbon monoxide
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in normal animal metabolism in low quantities, and is thought...
Approved
Investigational
Matched Synonyms: … Carbon monoxide ... carbon(II) oxide …
Matched Name: … Carbon monoxide …
Matched Description: … Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than ... The European Union has banned the use of carbon monoxide as a color stabilizer in meat and fish. ... inflammatory diseases of the lung and other organs. …
Matched Mixtures name: … Carbon Monoxide, Compressed Air Medical G.M. ... Carbon Monox, Helium, Oxygen, Nitrogen L.D.M. …
Matched Categories: … carbon monoxide ... Carbon Compounds, Inorganic …
Matched Name: … Carbon monoxide …
Matched Description: … Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than ... The European Union has banned the use of carbon monoxide as a color stabilizer in meat and fish. ... inflammatory diseases of the lung and other organs. …
Matched Mixtures name: … Carbon Monoxide, Compressed Air Medical G.M. ... Carbon Monox, Helium, Oxygen, Nitrogen L.D.M. …
Matched Categories: … carbon monoxide ... Carbon Compounds, Inorganic …
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. ... The sodium salt has been also used to treat primary pulmonary hypertension. …
Matched Salts name: … Epoprostenol sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Epoprostenol Sodium …
Matched Salts name: … Epoprostenol sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Epoprostenol Sodium …
Zinc chloride
Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Synonyms: … Zinc chloride …
Matched Name: … Zinc chloride …
Matched Description: … levels and prevent deficiency syndromes. ... [L14189] Zinc chloride was granted FDA approval before 26 June 1986.[L14189] ... Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc …
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Categories: … zinc chloride ... Chlorine Compounds ... Basic Ointments and Protectants ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Zinc Chloride ... Perioselect Zinc Chloride Solution 1% …
Matched Name: … Zinc chloride …
Matched Description: … levels and prevent deficiency syndromes. ... [L14189] Zinc chloride was granted FDA approval before 26 June 1986.[L14189] ... Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc …
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Categories: … zinc chloride ... Chlorine Compounds ... Basic Ointments and Protectants ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Zinc Chloride ... Perioselect Zinc Chloride Solution 1% …
Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Salts name: … Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … alendronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium …
Matched Salts name: … Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … alendronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium …
Silica dimethyl silylate
Experimental
Matched Synonyms: … Silica, hydrophobic colloidal …
Matched Name: … Silica dimethyl silylate …
Matched Name: … Silica dimethyl silylate …
Displaying drugs 576 - 600 of 1217 in total