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Displaying drugs 576 - 600 of 2626 in total
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and
Matched Salts name: … Venlafaxine hydrochloride
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Venlafaxine hydrochloride ... Venlafaxine Hydrochloride ... Venlafaxine Hydrochloride ER …
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … 3-(Carbomethoxy)pyridine ... 3-(Methoxycarbonyl)pyridine ... Nicotinic acid, methyl ester …
Matched Iupac: … methyl pyridine-3-carboxylate …
Matched Description: … muscle and joint pains [F64]. ... an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and ... methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Salts name: … Betaxolol hydrochloride
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Betaxolol Hydrochloride
A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Description: … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic …
Matched Salts name: … Acebutolol hydrochloride
Matched Categories: … acebutolol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … Acebutolol Hydrochloride
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … A drug that has been used in various urinary syndromes and as an antispasmodic. ... Its therapeutic usefulness and its mechanism of action are not clear. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … Flavoxate Hydrochloride
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and
Matched Salts name: … Paroxetine hydrochloride ... Paroxetine hydrochloride hemihydrate …
Matched Products: … Paroxetine Hydrochloride ... Paroxetine Hydrochloride CR ... Paroxetine Hydrochloride Anhydrous …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … L-Folinic acid ... (6S)-Folinic acid ... Levofolinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... As folate analogs, levoleucovorin and leucovorin are both used to counteract the toxic effects of folic ... Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic …
Matched Categories: … Folic Acid and Derivatives ... Folic Acid Analogues ... Enzymes and Coenzymes …
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and
Matched Salts name: … Maprotiline hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Maprotiline Hydrochloride
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Description: … and other conditions. ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain …
Matched Salts name: … Nortriptyline hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Nortriptyline Hydrochloride
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Acidum citricum ... Anhydrous citric acid ... Citric acid,anhydrous …
Matched Name: … Citric acid
Matched Iupac: … 2-hydroxypropane-1,2,3-tricarboxylic acid
Matched Description: … It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved …
Matched Mixtures name: … Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid ... Sodium Citrate and Citric Acid
Matched Salts name: … Citric acid monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Acid Preparations ... citric acid ... Carboxylic Acids
Matched Products: … Citric Acid ... Citric Acid Wipes …
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Memantine hydrochloride
Matched Categories: … donepezil, memantine and Ginkgo folium ... donepezil and memantine ... Excitatory Amino Acid Antagonists …
Matched Products: … Memantine Hydrochloride ... Memantine hydrochloride ... Mematine Hydrochloride
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Salts name: … Sevelamer hydrochloride
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Bile Acid Sequestrants …
Matched Products: … Sevelamer Hydrochloride ... Sevelamer hydrochloride
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Salts name: … Mitoxantrone hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Mitoxantrone Hydrochloride
Experimental
Matched Name: … 1'-Deazo-Thiamin Diphosphate …
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... gemcitabine is transformed into its active metabolites that work by replacing the building blocks of nucleic acids ... [L32950] It is also being investigated in other cancer and tumour types. …
Matched Salts name: … Gemcitabine hydrochloride
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Gemcitabine Hydrochloride ... Gemcitabine hydrochloride ... GEMCITABINE HYDROCHLORIDE
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992. …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Salts name: … Terbinafine hydrochloride
Matched Products: … Terbinafine Hydrochloride ... Terbinafine Hydochloride ... GoodSense Terbinafine Hydrochloride
Pyridoxamine has been used in trials studying the treatment of Kidney Stones.
Investigational
Matched Name: … Pyridoxamine
Matched Description: … Pyridoxamine has been used in trials studying the treatment of Kidney Stones. …
Matched Salts name: … Pyridoxamine hydrochloride ... Pyridoxamine phosphate …
Investigational
Matched Synonyms: … Folic acid, tetrahydro-n5,n10-methylene- ... 5,10-methylenetetrahydrofolic acid ... 5,10-methylene-(6rs)-tetrahydrofolic acid
Matched Iupac: … 4-{3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl}phenyl)formamido]pentanedioic acid
Matched Categories: … Enzymes and Coenzymes …
Iocetamic acid is a diagnostic aid (radiopaque medium)
Approved
Matched Synonyms: … Iocetamic acid ... Acido iocetamico ... Acidum iocetamicum …
Matched Name: … Iocetamic acid
Matched Iupac: … 3-[N-(3-amino-2,4,6-triiodophenyl)acetamido]-2-methylpropanoic acid
Matched Description: … Iocetamic acid is a diagnostic aid (radiopaque medium) …
Matched Categories: … iocetamic acid
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … Nicotinic acid methylamide ... 3-(Methylcarbamoyl)pyridine ... 3-(N-Methylcarbamoyl)pyridine
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids
Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase. Early reports of its activity...
Approved
Investigational
Matched Synonyms: … Dichloracetic acid
Matched Name: … Dichloroacetic acid
Matched Iupac: … 2,2-dichloroacetic acid
Matched Description: … and removal of a wide variety of skin and tissue lesions), but was cancelled post market. ... DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization ... Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Matched Products: … Bichloracetic Acid 100% …
Approved
Experimental
Matched Products: … ACID-NESS LOCIÓN …
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of...
Approved
Nutraceutical
Matched Synonyms: … Amber acid ... Acide succinique ... Succinic acid
Matched Name: … Succinic acid
Matched Iupac: … butanedioic acid
Matched Description: … , the manufacture of lacquers, and to make perfume esters. ... It is also used in foods as a sequestrant, buffer, and a neutralizing agent. ... (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical …
Matched Mixtures name: … Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium ... and Succinic Acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the synthesis ... [L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial …
Matched Salts name: … Vardenafil hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Vardenafil hydrochloride ... Vardenafil Hydrochloride
Displaying drugs 576 - 600 of 2626 in total