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Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Description: … Butenafine hydrochloride is a synthetic benzylamine antifungal agent. …
Matched Salts name: … Butenafine hydrochloride
Matched Products: … Tinactin Once-A-day Cream ... Butenafine Hydrochloride 1% ... Butenafine Hydrochloride
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Description: … It is proposed as a cardiotonic after myocardial infarction or open heart surgery. ... A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or …
Matched Mixtures name: … Dobutamine Hydrochloride in Dextrose …
Matched Salts name: … Dobutamine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Drugs that are Mainly Renally Excreted ... Compounds used in a research, industrial, or household setting …
Matched Products: … Dobutamine Hydrochloride ... DOBUTAMINE HYDROCHLORIDE ... Dobutamine Hydrochloride in Dextrose …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid ... N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … breast cancer and non-Hodgkin's lymphoma. ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... [A180322] This inhibition leads to suppression of inflammation as well as prevention of cell division …
Matched Salts cas: … 7413-34-5
Matched Salts name: … Methotrexate sodium
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … Methotrexate Sodium ... Ratio-methotrexate Sodium ... AC-VONDA …
Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. Its various salt forms and minerals play numerous roles...
Approved
Matched Name: … Fluoride ion …
Matched Iupac: … fluoride
Matched Description: … Its various salt forms and minerals play numerous roles as chemical reagents, industrial chemicals, and ... It also plays an essential physiological role, such as enhancing the resistance profile and strength ... Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine
Matched Mixtures name: … Multi-Vitamin Fluoride and Iron Drops ... Multi-Vitamin Fluoride Drops ... Multi-Vitamin Fluoride Drops …
Matched Products: … Topex Neutral pH Fluoride Gel Mint ... Topex Neutral pH Fluoride Gel Strawberry …
Experimental
Matched Synonyms: … 3',5'-ADP ... Adenosine 3'-phosphate-5'-phosphate ... 3'-Phosphoadenosine 5'-phosphate
Matched Name: … Adenosine 3',5'-diphosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}phosphonic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Trifluoro-thiamin phosphate
Matched Iupac: … 3-{[4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl}-4-methyl-5-[2-(phosphonatooxy)ethyl]-1,3-thiazol …
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Iupac: … (1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18 …
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as ... for an extended period. ... Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. …
Matched Mixtures name: … Oxycodone Hydrochloride and Aspirin ... Oxycodone Hydrochloride and Ibuprofen ... Oxycodone Hydrochloride and Acetaminophen …
Matched Salts name: … Oxycodone hydrochloride
Matched Categories: … oxycodone and acetylsalicylic acid ... oxycodone and naloxone ... oxycodone and ibuprofen ... oxycodone and naltrexone ... oxycodone and paracetamol …
Matched Products: … Oxycodone Hydrochloride ... Oxycodone Hydchloride ... Oxycodone hydrochloride
Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Iupac: … -2-(2-{2-[2-(2-{[(2S)-1-[(2S)-2-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-5- ... carbamoyl}propyl]carbamoyl}propyl]carbamoyl}pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl]carbamoyl}butanoic acid
Matched Description: … monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and ... Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride ... ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML) …
Investigational
Matched Synonyms: … Vitamin B13 ... Orotic acid ... Acido orotico …
Matched Name: … Orotic acid
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
Matched Categories: … Acids, Heterocyclic …
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-monophosphoric acid ester ... Pyridoxal 5-phosphate ... Pyridoxal 5'-phosphate
Matched Name: … Pyridoxal phosphate
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid
Matched Description: … This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters ... phosphate (pyridoxamine). ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal ... Vita-Rx Diabetic Vitamin
Matched Salts name: … Pyridoxal phosphate hydrate …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... pyridoxal phosphate ... Vitamins ... Vitamin B Complex …
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Synonyms: … 13-cis-Vitamin A acid ... Neovitamin A acid ... 13-cis-retinoic acid
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under ... Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. …
Matched Categories: … Skin and Mucous Membrane Agents ... Drugs that are Mainly Renally Excreted …
Matched Products: … ISOFACE 5 MG ... Ciscutan 5 mg - Kapseln ... ORATANE CAPSULE 5 mg …
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
Matched Description: … ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... , and mixed dyslipidemia. ... for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration …
Matched Mixtures name: … STAFEN®135 / 5 MG CAPSULAS …
Matched Categories: … Drugs that are Mainly Renally Excreted ... Peroxisome Proliferator Receptor alpha Agonist ... Acids, Acyclic ... Fibric Acids ... Carboxylic Acids
Matched Products: … Fenofibric Acid ... Fenofibric acid ... ACIDO FENOFIBRICO 135 MG …
Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
Matched Synonyms: … Combretastatin A4 phosphate ... Combretastatin A-4 phosphate ... 2-METHOXY-5-((Z)-2-(3,4,5-TRIMETHOXYPHENYL)VINYL)PHENYL DIHYDROGEN PHOSPHATE
Matched Iupac: … {2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy}phosphonic acid
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-ethyl-5-(sec-pentyl)barbituric acid ... 5-ethyl-5-(1-methylbutyl)barbituric acid ... 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) ... agent and is usually given orally. ... (From AMA Drug Evaluations Annual, 1994, p236) …
Matched Salts cas: … 57-33-0 …
Matched Salts name: … Pentobarbital Sodium
Matched Categories: … Hypnotics and Sedatives ... Drugs that are Mainly Renally Excreted …
Matched Products: … Nembutal Sodium ... Pentobarbital Sodium ... Nembutal Sodium Cap 100mg …
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Synonyms: … 5-sec-butyl-5-ethylbarbituric acid ... 5-ethyl-5-(1-methylpropyl)barbituric acid ... 5-ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-(butan-2-yl)-5-ethyl-1,3-diazinane-2,4,6-trione …
Matched Description: … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative ... [A201977,A201980] Butabarbital was granted FDA approval on 5 June 1939.[L13613] ... [A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Butabarbital sodium
Matched Categories: … Hypnotics and Sedatives ... Drugs that are Mainly Renally Excreted …
Matched Products: … Butisol Sodium ... Butisol Sodium Tab 30mg ... Butisol Sodium Tab 15mg …
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Synonyms: … 5-ethyl-5-isoamylbarbituric acid ... 5-ethyl-5-isopentylbarbituric acid ... 5-ethyl-5-(3-methylbutyl)barbituric acid
Matched Iupac: … 5-ethyl-5-(3-methylbutyl)-1,3-diazinane-2,4,6-trione …
Matched Description: … A barbiturate with hypnotic and sedative properties (but not antianxiety). ... Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Salts name: … Amobarbital sodium
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Amytal Sodium ... Amytal Sodium 500mg ... Amytal Sodium Cap 60mg …
Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Approved
Vet approved
Matched International brands: … Ak-Taine …
Matched Description: … It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt. ... Proparacaine is a topical anesthetic drug of the amino ester group. …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride
Matched Salts name: … Proparacaine hydrochloride
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Proparacaine Hydrochloride ... PMS-proparacaine Hydrochloride Oph Soltn 0.5% ... -parcaine Dps 5mg/ml …
Experimental
Matched Name: … Alpha-Ribazole-5'-Phosphate
Matched Iupac: … acid ... {[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Approved
Experimental
Matched Synonyms: … Thiamine diphosphate ... Thiamine pyrophosphate …
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}ethyl …
Matched Description: … It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase ... The coenzyme form of Vitamin B1 present in many animal tissues. …
Matched Salts cas: … 68684-55-9 …
Matched Categories: … Enzymes and Coenzymes ... Vitamins ... Vitamin B Complex …
ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for cancer.
Investigational
Matched Synonyms: … sodium bispiperidine-carboxamido-dimethylpenatnamido-methoxycarbonyl-indol-propanamidohexanoate …
Matched Description: … ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for …
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Synonyms: … 1-hydroxy-α-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester ... α-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester ... 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester …
Matched Description: … A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia. …
Matched Salts name: … Cyclopentolate hydrochloride
Matched Categories: … Mydriatics and Cycloplegics ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Ak-pentolate ... CICLOPENTOLATO AL 1 % ... SİKLOMİD % 1 GÖZ DAMLASI, 5 ML …
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Synonyms: … N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine …
Matched Description: … including allergic reactions, pain, sedation, nausea, and vomiting. ... Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine ... [A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications …
Matched Salts cas: … 17693-51-5 ... 58-33-3 …
Matched Mixtures name: … Promethazine Hydrochloride and Codeine Phosphate ... Promethazine Hydrochloride and Codeine Phosphate ... Promethazine Hydrochloride and Codeine Phosphate
Matched Salts name: … Promethazine hydrochloride
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics ... Acid Reducers ... Drugs that are Mainly Renally Excreted …
Matched Products: … DBL PROMETHAZINE HYDROCHLORIDE INJECTION BP 50 mg/2 ml ... Promethazine Hydrochloride ... Promethazine hydrochloride
5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Experimental
Matched Synonyms: … 5'-uridylic acid ... Uridine 5'-phosphoric acid ... Uridine phosphate
Matched Iupac: … acid ... {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Description: … 5'-Uridylic acid. ... A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … ’s and Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and
Matched Salts cas: … 111266-55-8 …
Matched Salts name: … Doxorubicin hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORUBICIN AU 2MG/ML 10MG ... DOXORUBICIN AU 2MG/ML 50MG ... DOXORUBICIN AU 2MG/ML200MG …
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]- …
Matched Iupac: … ]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. ... A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Matched Mixtures name: … CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET …
Matched Salts name: … Cefazolin sodium
Matched Categories: … Thiazines
Matched Products: … Cefazolin Sodium ... CEFAZOLIN SODIUM ... CEFAZOLINA SODICO 1 G …
Displaying drugs 576 - 600 of 5330 in total